| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Airway Obstruction | D000402 | 13 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Enterocolitis | D004760 | 3 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
Leukotriene b4
Leukotriene b4 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Chemotaxis, release of sequestered calcium ion into cytoplasm and Polymerization. Leukotriene b4 often locates in Protoplasm. The associated genes with Leukotriene b4 are phallacidin.
Cross Reference
Introduction
To understand associated biological information of Leukotriene b4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Leukotriene b4?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Leukotriene b4
PubChem Associated disorders and diseases
What pathways are associated with Leukotriene b4
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Leukotriene b4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Leukotriene b4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Leukotriene b4?
There are no associated biomedical information in the current reference collection.
What genes are associated with Leukotriene b4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Leukotriene b4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Leukotriene b4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Knight J et al. | Eicosanoid biosynthesis in an advanced deuterostomate invertebrate, the sea squirt (Ciona intestinalis). | 1999 | Biochim. Biophys. Acta | pmid:9989276 |
| Mayatepek E et al. | LTB4 and LTC4 are absent in the cerebrospinal fluid of human immunodeficiency virus type 1-seropositive persons with toxoplasmic encephalitis: evidence for inhibition of 5-lipoxygenase by Toxoplasma gondii. | 1999 | J. Infect. Dis. | pmid:9952384 |
| Lärfars G et al. | Activation of nitric oxide release and oxidative metabolism by leukotrienes B4, C4, and D4 in human polymorphonuclear leukocytes. | 1999 | Blood | pmid:9949184 |
| Hoglen NC et al. | Alteration of Kupffer cell function and morphology by low melt point paraffin wax in female Fischer-344 but not Sprague-Dawley rats. | 1998 | Toxicol. Sci. | pmid:9928681 |
| Martinsson T | Ropivacaine inhibits serum-induced proliferation of colon adenocarcinoma cells in vitro. | 1999 | J. Pharmacol. Exp. Ther. | pmid:9918572 |
| Igarashi T et al. | Characterization of the leukotriene B4 receptor in porcine leukocytes. Separation and reconstitution with heterotrimeric GTP-binding proteins. | 1999 | Eur. J. Biochem. | pmid:9914522 |
| Flynn MA et al. | Avian osteoclast cells are stimulated to resorb calcified matrices by and possess receptors for leukotriene B4. | 1999 | Calcif. Tissue Int. | pmid:9914324 |
| Eliakim R et al. | Effect of chronic nicotine administration on trinitrobenzene sulphonic acid-induced colitis. | 1998 | Eur J Gastroenterol Hepatol | pmid:9895047 |
| Nakao A et al. | Ubiquitous localization of leukotriene A4 hydrolase in the rat nephron. | 1999 | Kidney Int. | pmid:9893118 |
| Bannenberg G et al. | Leukotriene C4 is a tight-binding inhibitor of microsomal glutathione transferase-1. Effects of leukotriene pathway modifiers. | 1999 | J. Biol. Chem. | pmid:9890956 |
| Alanko J et al. | Modulation of arachidonic acid metabolism by phenols: relation to their structure and antioxidant/prooxidant properties. | 1999 | Free Radic. Biol. Med. | pmid:9890654 |
| Juergens UR et al. | The anti-inflammatory activity of L-menthol compared to mint oil in human monocytes in vitro: a novel perspective for its therapeutic use in inflammatory diseases. | 1998 | Eur. J. Med. Res. | pmid:9889172 |
| Nieto N et al. | Dietary monounsaturated n-3 and n-6 long-chain polyunsaturated fatty acids affect cellular antioxidant defense system in rats with experimental ulcerative colitis induced by trinitrobenzene sulfonic acid. | 1998 | Dig. Dis. Sci. | pmid:9881500 |
| Bucar F et al. | 5-Methylflavasperone and rhamnetin from Guiera senegalensis and their antioxidative and 5-lipoxygenase inhibitory activity. | 1998 | Pharmazie | pmid:9879572 |
| Dubé D et al. | Quinolines as potent 5-lipoxygenase inhibitors: synthesis and biological profile of L-746,530. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9871745 |
| Herencia F et al. | Synthesis and anti-inflammatory activity of chalcone derivatives. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9871729 |
| Powell WS et al. | 5-oxo-6,8,11,14-eicosatetraenoic acid is a potent stimulator of L-selectin shedding, surface expression of CD11b, actin polymerization, and calcium mobilization in human eosinophils. | 1999 | Am. J. Respir. Cell Mol. Biol. | pmid:9870930 |
| Kim JA et al. | Intracellular Ca2+ mediates lipoxygenase-induced proliferation of U-373 MG human astrocytoma cells. | 1998 | Arch. Pharm. Res. | pmid:9868534 |
| Phare SM et al. | Alveolar lining fluid regulates mononuclear phagocyte 5-lipoxygenase metabolism. | 1998 | Eur. Respir. J. | pmid:9864011 |
| Wheelan P et al. | Metabolic transformations of leukotriene B4 in primary cultures of human hepatocytes. | 1999 | J. Pharmacol. Exp. Ther. | pmid:9862787 |
| Jackson WT et al. | Pharmacologic actions of the second-generation leukotriene B4 receptor antagonist LY293111: in vitro studies. | 1999 | J. Pharmacol. Exp. Ther. | pmid:9862783 |
| Sorenson WG et al. | Cell wall preparations from environmental yeasts: effect on alveolar macrophage function in vitro. | 1998 | Ann Agric Environ Med | pmid:9852493 |
| Masubuchi T et al. | Smoke extract stimulates lung epithelial cells to release neutrophil and monocyte chemotactic activity. | 1998 | Am. J. Pathol. | pmid:9846980 |
| Koyama S et al. | Bradykinin stimulates type II alveolar cells to release neutrophil and monocyte chemotactic activity and inflammatory cytokines. | 1998 | Am. J. Pathol. | pmid:9846978 |
| Lauredo IT et al. | Mechanism of pyocyanin- and 1-hydroxyphenazine-induced lung neutrophilia in sheep airways. | 1998 | J. Appl. Physiol. | pmid:9843556 |
| Casale TB et al. | The sequential migration of neutrophils through endothelium and epithelium: a new model system. | 1998 Nov-Dec | Exp. Lung Res. | pmid:9839160 |
| Longo WE et al. | The role of cyclooxygenase-1 and cyclooxygenase-2 in lipopolysaccharide and interleukin-1 stimulated enterocyte prostanoid formation. | 1998 | Mediators Inflamm. | pmid:9836494 |
| Ohashi H et al. | Sulochrin inhibits eosinophil activation and chemotaxis. | 1998 | Inflamm. Res. | pmid:9831326 |
| Horizoe T et al. | ER-34122, a novel dual 5-lipoxygenase/cyclooxygenase inhibitor with potent anti-inflammatory activity in an arachidonic acid-induced ear inflammation model. | 1998 | Inflamm. Res. | pmid:9831321 |
| Usami Y et al. | Chitin and chitosan stimulate canine polymorphonuclear cells to release leukotriene B4 and prostaglandin E2. | 1998 | J. Biomed. Mater. Res. | pmid:9827674 |
| Roland IH et al. | Effect of hydroxyethylrutosides on hypoxial-induced neutrophil adherence to umbilical vein endothelium. | 1998 | Cardiovasc Drugs Ther | pmid:9825183 |
| Takafuji S et al. | Release of granule proteins from human eosinophils stimulated with mast-cell mediators. | 1998 | Allergy | pmid:9821474 |
| Kjellström S et al. | On-line coupling of microdialysis sampling with liquid chromatography for the determination of peptide and non-peptide leukotrienes. | 1998 | J Chromatogr A | pmid:9818423 |
| Frommel TO et al. | Effect of aspirin on prostaglandin E2 and leukotriene B4 production in human colonic mucosa from cancer patients. | 1997 | Clin. Cancer Res. | pmid:9815674 |
| Salas A et al. | Mechanisms responsible for enhanced inflammatory response to ischemia-reperfusion in diabetes. | 1998 | Am. J. Physiol. | pmid:9815085 |
| Denizot Y et al. | Effects of lipid mediators on the synthesis of leukaemia inhibitory factor and interleukin 6 by human bone marrow stromal cells. | 1998 | Cytokine | pmid:9811531 |
| Juergens UR et al. | Inhibition of cytokine production and arachidonic acid metabolism by eucalyptol (1.8-cineole) in human blood monocytes in vitro. | 1998 | Eur. J. Med. Res. | pmid:9810029 |
| Tavares de Lima W et al. | Lipid mediators, tumor necrosis factor and nitric oxide and their interactions in immune-complex-induced lung injury. | 1998 | Eur. J. Pharmacol. | pmid:9809871 |
| Frieri M et al. | Allergen-stimulated leukotriene B4 and interleukin-8 levels in patients with asthma and allergic rhinitis-modulation by a lipid pathway inhibitor. | 1998 | Ann. Allergy Asthma Immunol. | pmid:9809497 |
| Surette ME et al. | Mechanisms of the priming effect of lipopolysaccharides on the biosynthesis of leukotriene B4 in chemotactic peptide-stimulated human neutrophils. | 1998 | FASEB J. | pmid:9806761 |
| Battu S et al. | Cyclooxygenase-2 up-regulation after FLAP transfection in human adenocarcinoma cell line HT29 cl.19A. | 1998 | FEBS Lett. | pmid:9804170 |
| Matsushita N et al. | Pharmacological studies on the novel antiallergic drug HQL-79: II. Elucidation of mechanisms for antiallergic and antiasthmatic effects. | 1998 | Jpn. J. Pharmacol. | pmid:9804057 |
| Ohtsuka Y et al. | Chronic oral antigen exposure induces lymphocyte migration in anaphylactic mouse intestine. | 1998 | Pediatr. Res. | pmid:9803464 |
| Jin R et al. | Role of human CYP4F2 in hepatic catabolism of the proinflammatory agent leukotriene B4. | 1998 | Arch. Biochem. Biophys. | pmid:9799565 |
| Yu DS et al. | Pathogenesis of ischemia reperfusion injury of the kidney after transient renal arterial clamping in rats. | 1998 | J. Formos. Med. Assoc. | pmid:9795528 |
| Ghosh J and Myers CE | Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9789062 |
| Akman A et al. | Effect of lodoxamide on tear leukotriene levels in giant papillary conjunctivitis associated with ocular prosthesis. | 1998 | Ocul. Immunol. Inflamm. | pmid:9785608 |
| Zetterlund A et al. | Effects of beta2-agonists and budesonide on interleukin-1beta and leukotriene B4 secretion: studies of human monocytes and alveolar macrophages. | 1998 | J Asthma | pmid:9777883 |
| Baset HA et al. | Molecular cloning and functional expression of a Caenorhabditis elegans aminopeptidase structurally related to mammalian leukotriene A4 hydrolases. | 1998 | J. Biol. Chem. | pmid:9774412 |
| Perez S et al. | Inhibition by the anti-mitotic drug doxorubicin of platelet-activating-factor-induced late eosinophil accumulation in rats. | 1998 | Eur. J. Pharmacol. | pmid:9774255 |