Leukotriene b4

Leukotriene b4 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Chemotaxis, release of sequestered calcium ion into cytoplasm and Polymerization. Leukotriene b4 often locates in Protoplasm. The associated genes with Leukotriene b4 are phallacidin.

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Introduction

To understand associated biological information of Leukotriene b4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Leukotriene b4

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Hypoxia D000860 23 associated lipids
Adenocarcinoma D000230 166 associated lipids
Enterocolitis D004760 3 associated lipids
Breast Neoplasms D001943 24 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Leukotriene b4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Leukotriene b4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Leukotriene b4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

What genes are associated with Leukotriene b4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Leukotriene b4

Download all related citations
Per page 10 20 50 100 | Total 5221
Authors Title Published Journal PubMed Link
Vaivoda R et al. CYP4F18-Deficient Neutrophils Exhibit Increased Chemotaxis to Complement Component C5a. 2015 J Immunol Res pmid:26613087
Homann J et al. In Vivo Availability of Pro-Resolving Lipid Mediators in Oxazolone Induced Dermal Inflammation in the Mouse. 2015 PLoS ONE pmid:26599340
Liu X et al. Leukotriene B4 Inhibits L-Type Calcium Channels via p38 Signaling Pathway in Vascular Smooth Muscle Cells. 2015 Cell. Physiol. Biochem. pmid:26584289
Qian J et al. Leukotriene B4 Activates Pulmonary Artery Adventitial Fibroblasts in Pulmonary Hypertension. 2015 Hypertension pmid:26558820
Zoccal KF et al. PPAR-γ activation by Tityus serrulatus venom regulates lipid body formation and lipid mediator production. 2015 Toxicon pmid:25450800
Gendelman O et al. A randomized double-blind placebo-controlled study adding high dose vitamin D to analgesic regimens in patients with musculoskeletal pain. 2015 Lupus pmid:25801891
Hoffmeyer F et al. Evaluation of Airway Inflammation in Compost Workers Exposed to Bioaerosols Using Exhaled Breath Condensate and Fractional Exhaled Nitric Oxide. 2015 Adv. Exp. Med. Biol. pmid:25786401
de Cássia Campos MR et al. Differential effects of chemoattractants on mast cell recruitment in vivo. 2014 May-Jun Cell. Immunol. pmid:24736098
Breganó JW et al. Comparison of selective and non selective cyclo-oxygenase 2 inhibitors in experimental colitis exacerbation: role of leukotriene B4 and superoxide dismutase. 2014 Jul-Sep Arq Gastroenterol pmid:25296084
Keijsers RR et al. In vivo induction of cutaneous inflammation results in the accumulation of extracellular trap-forming neutrophils expressing RORγt and IL-17. 2014 J. Invest. Dermatol. pmid:24317395
Stsiapanava A et al. Product formation controlled by substrate dynamics in leukotriene A4 hydrolase. 2014 Biochim. Biophys. Acta pmid:24333438
Sharma-Walia N et al. The Kaposi's sarcoma-associated herpesvirus (KSHV)-induced 5-lipoxygenase-leukotriene B4 cascade plays key roles in KSHV latency, monocyte recruitment, and lipogenesis. 2014 J. Virol. pmid:24335295
Guan WJ et al. Exhaled breath condensate eicosanoid levels in asthma: still questioned. 2014 J. Allergy Clin. Immunol. pmid:24530097
Paige M et al. Role of leukotriene A4 hydrolase aminopeptidase in the pathogenesis of emphysema. 2014 J. Immunol. pmid:24771855
Sorensen LS et al. Effects of perioperative supplementation with omega-3 fatty acids on leukotriene Bâ‚„ and leukotriene Bâ‚… production by stimulated neutrophils in patients with colorectal cancer: a randomized, placebo-controlled intervention trial. 2014 Nutrients pmid:25268838
Bukiya AN et al. Activation of calcium- and voltage-gated potassium channels of large conductance by leukotriene B4. 2014 J. Biol. Chem. pmid:25371198
Leaker BR et al. The effect of the novel phosphodiesterase-4 inhibitor MEM 1414 on the allergen induced responses in mild asthma. 2014 BMC Pulm Med pmid:25351474
Di Gennaro A and Haeggström JZ Targeting leukotriene B4 in inflammation. 2014 Expert Opin. Ther. Targets pmid:24090264
Joshi YB et al. Modulation of amyloid-β production by leukotriene B4 via the γ-secretase pathway. 2014 J. Alzheimers Dis. pmid:24008686
Estevão-Silva CF et al. Anethole and eugenol reduce in vitro and in vivo leukocyte migration induced by fMLP, LTB4, and carrageenan. 2014 J Nat Med pmid:24789168