Leukotriene b4

Leukotriene b4 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Chemotaxis, release of sequestered calcium ion into cytoplasm and Polymerization. Leukotriene b4 often locates in Protoplasm. The associated genes with Leukotriene b4 are phallacidin.

Cross Reference

Introduction

To understand associated biological information of Leukotriene b4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Leukotriene b4

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Hypoxia D000860 23 associated lipids
Adenocarcinoma D000230 166 associated lipids
Enterocolitis D004760 3 associated lipids
Breast Neoplasms D001943 24 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Leukotriene b4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Leukotriene b4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Leukotriene b4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

What genes are associated with Leukotriene b4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Leukotriene b4

Download all related citations
Per page 10 20 50 100 | Total 5221
Authors Title Published Journal PubMed Link
Pardo V et al. Opposite cross-talk by oleate and palmitate on insulin signaling in hepatocytes through macrophage activation. 2015 J. Biol. Chem. pmid:25792746
Li P et al. LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes. 2015 Nat. Med. pmid:25706874
Filgueiras LR et al. Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes. 2015 Sci Signal pmid:25628460
Tateishi N et al. Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E2 content in rat adjuvant-induced arthritis model. 2015 Lipids Health Dis pmid:25595700
Fahel JS et al. 5-Lipoxygenase negatively regulates Th1 response during Brucella abortus infection in mice. 2015 Infect. Immun. pmid:25583526
Piotrowska-Tomala KK et al. Lipopolysaccharides, cytokines, and nitric oxide affect secretion of prostaglandins and leukotrienes by bovine mammary gland during experimentally induced mastitis in vivo and in vitro. 2015 Domest. Anim. Endocrinol. pmid:25935895
Minutoli L et al. A dual inhibitor of cyclooxygenase and 5-lipoxygenase protects against kainic acid-induced brain injury. 2015 Neuromolecular Med. pmid:25893744
de Cássia Campos MR et al. Differential effects of chemoattractants on mast cell recruitment in vivo. 2014 May-Jun Cell. Immunol. pmid:24736098
Breganó JW et al. Comparison of selective and non selective cyclo-oxygenase 2 inhibitors in experimental colitis exacerbation: role of leukotriene B4 and superoxide dismutase. 2014 Jul-Sep Arq Gastroenterol pmid:25296084
Wang Z et al. Leukotriene B4 enhances the generation of proinflammatory microRNAs to promote MyD88-dependent macrophage activation. 2014 J. Immunol. pmid:24477912
Laidlaw TM et al. Prostaglandin E2 resistance in granulocytes from patients with aspirin-exacerbated respiratory disease. 2014 J. Allergy Clin. Immunol. pmid:24486071
Yoo JM et al. Anti-allergic action of aged black garlic extract in RBL-2H3 cells and passive cutaneous anaphylaxis reaction in mice. 2014 J Med Food pmid:24456359
Cho H et al. On-demand, competing gradient arrays for neutrophil chemotaxis. 2014 Lab Chip pmid:24430002
Shang E et al. De novo design of multitarget ligands with an iterative fragment-growing strategy. 2014 J Chem Inf Model pmid:24611712
Kubala SA et al. Pathogen induced chemo-attractant hepoxilin A3 drives neutrophils, but not eosinophils across epithelial barriers. 2014 Prostaglandins Other Lipid Mediat. pmid:24315875
Zhang D et al. Glucocorticoids sensitize rat placental inflammatory responses via inhibiting lipoxin A4 biosynthesis. 2014 Biol. Reprod. pmid:24571985
Araújo-Santos T et al. Prostaglandin E2/leukotriene B4 balance induced by Lutzomyia longipalpis saliva favors Leishmania infantum infection. 2014 Parasit Vectors pmid:25526785
O'Sullivan A et al. Habitual diets rich in dark-green vegetables are associated with an increased response to ω-3 fatty acid supplementation in Americans of African ancestry. 2014 J. Nutr. pmid:24259553
Ribeiro D et al. Inhibition of LOX by flavonoids: a structure-activity relationship study. 2014 Eur J Med Chem pmid:24368208
Monteiro AP et al. Pivotal role of the 5-lipoxygenase pathway in lung injury after experimental sepsis. 2014 Am. J. Respir. Cell Mol. Biol. pmid:23947598