Leukotriene b4

Leukotriene b4 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Chemotaxis, release of sequestered calcium ion into cytoplasm and Polymerization. Leukotriene b4 often locates in Protoplasm. The associated genes with Leukotriene b4 are phallacidin.

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Introduction

To understand associated biological information of Leukotriene b4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Leukotriene b4

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Hypoxia D000860 23 associated lipids
Adenocarcinoma D000230 166 associated lipids
Enterocolitis D004760 3 associated lipids
Breast Neoplasms D001943 24 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Leukotriene b4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Leukotriene b4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Leukotriene b4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

What genes are associated with Leukotriene b4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Leukotriene b4

Download all related citations
Per page 10 20 50 100 | Total 5221
Authors Title Published Journal PubMed Link
Cossette C et al. Biosynthesis and actions of 5-oxoeicosatetraenoic acid (5-oxo-ETE) on feline granulocytes. 2015 Biochem. Pharmacol. pmid:26032638
Jiang JX et al. EETs Attenuate Ox-LDL-Induced LTB4 Production and Activity by Inhibiting p38 MAPK Phosphorylation and 5-LO/BLT1 Receptor Expression in Rat Pulmonary Arterial Endothelial Cells. 2015 PLoS ONE pmid:26035589
Colom B et al. Leukotriene B4-Neutrophil Elastase Axis Drives Neutrophil Reverse Transendothelial Cell Migration In Vivo. 2015 Immunity pmid:26047922
Khan M et al. Oral administration of cytosolic PLA2 inhibitor arachidonyl trifluoromethyl ketone ameliorates cauda equina compression injury in rats. 2015 J Neuroinflammation pmid:25971887
Jensen GS et al. Anti-inflammatory properties of a dried fermentate in vitro and in vivo. 2015 J Med Food pmid:25105458
Gendelman O et al. A randomized double-blind placebo-controlled study adding high dose vitamin D to analgesic regimens in patients with musculoskeletal pain. 2015 Lupus pmid:25801891
Hoffmeyer F et al. Evaluation of Airway Inflammation in Compost Workers Exposed to Bioaerosols Using Exhaled Breath Condensate and Fractional Exhaled Nitric Oxide. 2015 Adv. Exp. Med. Biol. pmid:25786401
de Cássia Campos MR et al. Differential effects of chemoattractants on mast cell recruitment in vivo. 2014 May-Jun Cell. Immunol. pmid:24736098
Breganó JW et al. Comparison of selective and non selective cyclo-oxygenase 2 inhibitors in experimental colitis exacerbation: role of leukotriene B4 and superoxide dismutase. 2014 Jul-Sep Arq Gastroenterol pmid:25296084
Secatto A et al. The leukotriene B₄/BLT₁ axis is a key determinant in susceptibility and resistance to histoplasmosis. 2014 PLoS ONE pmid:24465479
Byrne MB et al. Oscillatory behavior of neutrophils under opposing chemoattractant gradients supports a winner-take-all mechanism. 2014 PLoS ONE pmid:24465668
Tavares NM et al. Understanding the mechanisms controlling Leishmania amazonensis infection in vitro: the role of LTB4 derived from human neutrophils. 2014 J. Infect. Dis. pmid:24634497
Cheung KL et al. Nrf2 knockout enhances intestinal tumorigenesis in Apc(min/+) mice due to attenuation of anti-oxidative stress pathway while potentiates inflammation. 2014 Mol. Carcinog. pmid:22911891
Kaźmierczak M et al. Correlation of inflammatory markers with echocardiographic parameters of left and right ventricular function in patients with chronic obstructive pulmonary disease and cardiovascular diseases. 2014 Pol. Arch. Med. Wewn. pmid:24824617
Fischer CD et al. Tulathromycin exerts proresolving effects in bovine neutrophils by inhibiting phospholipases and altering leukotriene B4, prostaglandin E2, and lipoxin A4 production. 2014 Antimicrob. Agents Chemother. pmid:24820086
Anderson R et al. The beta-2-adrenoreceptor agonists, formoterol and indacaterol, but not salbutamol, effectively suppress the reactivity of human neutrophils in vitro. 2014 Mediators Inflamm. pmid:24733958
Drozdovszky O et al. Sputum eicosanoid profiling in exacerbations of chronic obstructive pulmonary disease. 2014 Respiration pmid:24714447
Mendes MT and Silveira PF The interrelationship between leukotriene B4 and leukotriene-A4-hydrolase in collagen/adjuvant-induced arthritis in rats. 2014 Biomed Res Int pmid:24701582
Liu YH et al. Hydrogen sulfide prevents heart failure development via inhibition of renin release from mast cells in isoproterenol-treated rats. 2014 Antioxid. Redox Signal. pmid:23581627
Moshkovits I et al. CMRF35-like molecule 1 (CLM-1) regulates eosinophil homeostasis by suppressing cellular chemotaxis. 2014 Mucosal Immunol pmid:23820751