LTC4

Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.

Cross Reference

Introduction

To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with LTC4?

LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with LTC4

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Edema D004487 152 associated lipids
Inflammation D007249 119 associated lipids
Glioma D005910 112 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Brain Ischemia D002545 89 associated lipids
Atherosclerosis D050197 85 associated lipids
Stomach Ulcer D013276 75 associated lipids
Leukemia D007938 74 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Colitis D003092 69 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Reperfusion Injury D015427 65 associated lipids
Asthma D001249 52 associated lipids
Osteosarcoma D012516 50 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Arthritis D001168 41 associated lipids
Hypotension D007022 41 associated lipids
Peritonitis D010538 38 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Glomerulonephritis D005921 35 associated lipids
Anaphylaxis D000707 35 associated lipids
Burns D002056 34 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Drug Eruptions D003875 30 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Angina Pectoris D000787 27 associated lipids
Gastritis D005756 27 associated lipids
Nasal Polyps D009298 26 associated lipids
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Carcinoma, Small Cell D018288 21 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Cough D003371 19 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Leukemia, Myelogenous, Chronic, BCR-ABL Positive D015464 17 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Ulcer D014456 16 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Uveitis D014605 14 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Airway Obstruction D000402 13 associated lipids
Acute-Phase Reaction D000210 12 associated lipids
Myocardial Ischemia D017202 11 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Respiratory Syncytial Virus Infections D018357 10 associated lipids
Asthma, Exercise-Induced D001250 10 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Asbestosis D001195 8 associated lipids
Ear Diseases D004427 7 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Pneumococcal Infections D011008 7 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Rhinitis, Allergic, Perennial D012221 6 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Mesenteric Vascular Occlusion D008641 4 associated lipids
Eosinophilia D004802 4 associated lipids
Insect Bites and Stings D007299 4 associated lipids
Status Asthmaticus D013224 4 associated lipids
Wounds, Nonpenetrating D014949 4 associated lipids
Eosinophilic Esophagitis D057765 3 associated lipids
Common Bile Duct Diseases D003137 3 associated lipids
Hyperbilirubinemia, Hereditary D006933 3 associated lipids
Cestode Infections D002590 3 associated lipids
Neointima D058426 3 associated lipids
Pseudoxanthoma Elasticum D011561 2 associated lipids
Phlebitis D010689 1 associated lipids
Per page 10 20 50 100 | Total 75

PubChem Associated disorders and diseases

What pathways are associated with LTC4

Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with LTC4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with LTC4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with LTC4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with LTC4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with LTC4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with LTC4

Download all related citations
Per page 10 20 50 100 | Total 1173
Authors Title Published Journal PubMed Link
Hong JT and Glauert HP Comitogenicity of eicosanoids and the peroxisome proliferator ciprofibrate in cultured rat hepatocytes. 1996 J. Cell. Physiol. pmid:8908198
Geirsson A et al. Potentiating effects of pertussis toxin on leukotriene C4 induced formation of inositol phosphate and prostacyclin in human umbilical vein endothelial cells. 1998 J. Cell. Physiol. pmid:9731750
Mayer R et al. Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes. 1995 J. Cell Biol. pmid:7559771
Garcia C et al. Effects of synthetic peptido-leukotrienes on bone resorption in vitro. 1996 J. Bone Miner. Res. pmid:8992883
Qian YM et al. Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: evidence of differential interactions with NH2- and COOH-proximal halves of the protein. 2001 J. Biol. Chem. pmid:11507101
Ito K et al. Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity. 2001 J. Biol. Chem. pmid:11500505
Scoggan KA et al. Production of leukotriene C4 in different human tissues is attributable to distinct membrane bound biosynthetic enzymes. 1997 J. Biol. Chem. pmid:9092565
Iliás A et al. Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6). 2002 J. Biol. Chem. pmid:11880368
Carter BZ et al. Metabolism of leukotriene C4 in gamma-glutamyl transpeptidase-deficient mice. 1997 J. Biol. Chem. pmid:9139674
Metters KM et al. Microsomal glutathione S-transferase is the predominant leukotriene C4 binding site in cellular membranes. 1994 J. Biol. Chem. pmid:8175695
Campbell JD et al. Molecular modeling correctly predicts the functional importance of Phe594 in transmembrane helix 11 of the multidrug resistance protein, MRP1 (ABCC1). 2004 J. Biol. Chem. pmid:14561746
Bandeira-Melo C et al. Extranuclear lipid bodies, elicited by CCR3-mediated signaling pathways, are the sites of chemokine-enhanced leukotriene C4 production in eosinophils and basophils. 2001 J. Biol. Chem. pmid:11274187
Zhao Q and Chang XB Mutation of the aromatic amino acid interacting with adenine moiety of ATP to a polar residue alters the properties of multidrug resistance protein 1. 2004 J. Biol. Chem. pmid:15355964
Zhang DW et al. Identification of an amino acid residue in multidrug resistance protein 1 critical for conferring resistance to anthracyclines. 2001 J. Biol. Chem. pmid:11278596
Furumoto Y et al. The FcepsilonRIbeta immunoreceptor tyrosine-based activation motif exerts inhibitory control on MAPK and IkappaB kinase phosphorylation and mast cell cytokine production. 2004 J. Biol. Chem. pmid:15355979
Ito K et al. Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport. 2001 J. Biol. Chem. pmid:11278867
Puder M and Soberman RJ Glutathione conjugates recognize the Rossmann fold of glyceraldehyde-3-phosphate dehydrogenase. 1997 J. Biol. Chem. pmid:9099752
Morii E and Oboki K MITF is necessary for generation of prostaglandin D2 in mouse mast cells. 2004 J. Biol. Chem. pmid:15375155
Situ D et al. Mutational analysis of ionizable residues proximal to the cytoplasmic interface of membrane spanning domain 3 of the multidrug resistance protein, MRP1 (ABCC1): glutamate 1204 is important for both the expression and catalytic activity of the transporter. 2004 J. Biol. Chem. pmid:15208328
Zhang DW et al. Identification of a nonconserved amino acid residue in multidrug resistance protein 1 important for determining substrate specificity: evidence for functional interaction between transmembrane helices 14 and 17. 2001 J. Biol. Chem. pmid:11429411
Loe DW et al. Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport. 1996 J. Biol. Chem. pmid:8621643
Gao M et al. Reconstitution of ATP-dependent leukotriene C4 transport by Co-expression of both half-molecules of human multidrug resistance protein in insect cells. 1996 J. Biol. Chem. pmid:8910374
Chang WC and Parekh AB Close functional coupling between Ca2+ release-activated Ca2+ channels, arachidonic acid release, and leukotriene C4 secretion. 2004 J. Biol. Chem. pmid:15133023
Chang WC et al. Local Ca2+ influx through Ca2+ release-activated Ca2+ (CRAC) channels stimulates production of an intracellular messenger and an intercellular pro-inflammatory signal. 2008 J. Biol. Chem. pmid:18156181
Satake Y et al. Role of group V phospholipase A2 in zymosan-induced eicosanoid generation and vascular permeability revealed by targeted gene disruption. 2004 J. Biol. Chem. pmid:14761945
Haimeur A et al. Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity. 2002 J. Biol. Chem. pmid:12186871
Zhang DW et al. Determinants of the substrate specificity of multidrug resistance protein 1: role of amino acid residues with hydrogen bonding potential in predicted transmembrane helix 17. 2002 J. Biol. Chem. pmid:11925441
Loe DW et al. ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids. 1996 J. Biol. Chem. pmid:8621644
Maekawa A et al. Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses. 2002 J. Biol. Chem. pmid:11932261
Ahamed J and Ali H Distinct roles of receptor phosphorylation, G protein usage, and mitogen-activated protein kinase activation on platelet activating factor-induced leukotriene C(4) generation and chemokine production. 2002 J. Biol. Chem. pmid:11934880
Gao M et al. Multidrug resistance protein. Identification of regions required for active transport of leukotriene C4. 1998 J. Biol. Chem. pmid:9553138
Iram SH and Cole SP Mutation of Glu521 or Glu535 in cytoplasmic loop 5 causes differential misfolding in multiple domains of multidrug and organic anion transporter MRP1 (ABCC1). 2012 J. Biol. Chem. pmid:22232552
Mao Q et al. GSH-dependent photolabeling of multidrug resistance protein MRP1 (ABCC1) by [125I]LY475776. Evidence of a major binding site in the COOH-proximal membrane spanning domain. 2002 J. Biol. Chem. pmid:12034727
Sakamoto H et al. Involvement of phospholipid hydroperoxide glutathione peroxidase in the modulation of prostaglandin D2 synthesis. 2000 J. Biol. Chem. pmid:11010961
Fernández SB et al. Role of the N-terminal transmembrane region of the multidrug resistance protein MRP2 in routing to the apical membrane in MDCKII cells. 2002 J. Biol. Chem. pmid:12060660
Leslie EM et al. Transport of the beta -O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1). Requirement for glutathione or a non-sulfur-containing analog. 2001 J. Biol. Chem. pmid:11375986
Saino H et al. The catalytic architecture of leukotriene C4 synthase with two arginine residues. 2011 J. Biol. Chem. pmid:21454538
He P et al. Oxidative stress suppresses cysteinyl leukotriene generation by mouse bone marrow-derived mast cells. 2011 J. Biol. Chem. pmid:21233206
Koike K et al. Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1. 2002 J. Biol. Chem. pmid:12388549
Iram SH and Cole SP Expression and function of human MRP1 (ABCC1) is dependent on amino acids in cytoplasmic loop 5 and its interface with nucleotide binding domain 2. 2011 J. Biol. Chem. pmid:21177244
Yang Y et al. Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1. 2002 J. Biol. Chem. pmid:12235150
Büchler M et al. cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats. 1996 J. Biol. Chem. pmid:8662992
Blokzijl H et al. Up-regulation and cytoprotective role of epithelial multidrug resistance-associated protein 1 in inflammatory bowel disease. 2008 J. Biol. Chem. pmid:18838379
Yang R et al. ATP binding to the first nucleotide binding domain of multidrug resistance-associated protein plays a regulatory role at low nucleotide concentration, whereas ATP hydrolysis at the second plays a dominant role in ATP-dependent leukotriene C4 transport. 2003 J. Biol. Chem. pmid:12783859
Muñoz NM et al. Human group V phospholipase A2 induces group IVA phospholipase A2-independent cysteinyl leukotriene synthesis in human eosinophils. 2003 J. Biol. Chem. pmid:12796497
Zhang DW et al. Functional importance of polar and charged amino acid residues in transmembrane helix 14 of multidrug resistance protein 1 (MRP1/ABCC1): identification of an aspartate residue critical for conversion from a high to low affinity substrate binding state. 2003 J. Biol. Chem. pmid:12954620
Niegowski D et al. Crystal structures of leukotriene C4 synthase in complex with product analogs: implications for the enzyme mechanism. 2014 J. Biol. Chem. pmid:24366866
Konno T et al. Identification of domains participating in the substrate specificity and subcellular localization of the multidrug resistance proteins MRP1 and MRP2. 2003 J. Biol. Chem. pmid:12682044
Yamane Y et al. Expression of multidrug resistance protein/GS-X pump and gamma-glutamylcysteine synthetase genes is regulated by oxidative stress. 1998 J. Biol. Chem. pmid:9813007
Carter BZ et al. gamma-glutamyl leukotrienase, a gamma-glutamyl transpeptidase gene family member, is expressed primarily in spleen. 1998 J. Biol. Chem. pmid:9774450
Wijewickrama GT et al. Systematic evaluation of transcellular activities of secretory phospholipases A2. High activity of group V phospholipases A2 to induce eicosanoid biosynthesis in neighboring inflammatory cells. 2006 J. Biol. Chem. pmid:16476735
Hipfner DR et al. Monoclonal antibodies that inhibit the transport function of the 190-kDa multidrug resistance protein, MRP. Localization of their epitopes to the nucleotide-binding domains of the protein. 1999 J. Biol. Chem. pmid:10336431
Leier I et al. The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates. 1994 J. Biol. Chem. pmid:7961706
Payen LF et al. Role of carboxylate residues adjacent to the conserved core Walker B motifs in the catalytic cycle of multidrug resistance protein 1 (ABCC1). 2003 J. Biol. Chem. pmid:12882957
Bannenberg G et al. Leukotriene C4 is a tight-binding inhibitor of microsomal glutathione transferase-1. Effects of leukotriene pathway modifiers. 1999 J. Biol. Chem. pmid:9890956
Kanaoka Y et al. Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligand. 2013 J. Biol. Chem. pmid:23504326
Bukiya AN et al. Activation of calcium- and voltage-gated potassium channels of large conductance by leukotriene B4. 2014 J. Biol. Chem. pmid:25371198
Murakami M et al. Interleukin-3 regulates development of the 5-lipoxygenase/leukotriene C4 synthase pathway in mouse mast cells. 1995 J. Biol. Chem. pmid:7559381
Gao M et al. Comparison of the functional characteristics of the nucleotide binding domains of multidrug resistance protein 1. 2000 J. Biol. Chem. pmid:10777615
Li L et al. Identification of glutathione as a driving force and leukotriene C4 as a substrate for oatp1, the hepatic sinusoidal organic solute transporter. 1998 J. Biol. Chem. pmid:9632674
Perrotton T et al. (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1. 2007 J. Biol. Chem. pmid:17646169
Bates ME et al. ERK1 and ERK2 activation by chemotactic factors in human eosinophils is interleukin 5-dependent and contributes to leukotriene C(4) biosynthesis. 2000 J. Biol. Chem. pmid:10753897
Thompson C et al. Signaling by the cysteinyl-leukotriene receptor 2. Involvement in chemokine gene transcription. 2008 J. Biol. Chem. pmid:18048362
Qian YM et al. Glutathione stimulates sulfated estrogen transport by multidrug resistance protein 1. 2001 J. Biol. Chem. pmid:11102445
Murakami M et al. Distinct arachidonate-releasing functions of mammalian secreted phospholipase A2s in human embryonic kidney 293 and rat mastocytoma RBL-2H3 cells through heparan sulfate shuttling and external plasma membrane mechanisms. 2001 J. Biol. Chem. pmid:11106649
Falcón-Pérez JM et al. Functional domain analysis of the yeast ABC transporter Ycf1p by site-directed mutagenesis. 1999 J. Biol. Chem. pmid:10438540
Alswied A and Parekh AB Ca2+ Influx through Store-operated Calcium Channels Replenishes the Functional Phosphatidylinositol 4,5-Bisphosphate Pool Used by Cysteinyl Leukotriene Type I Receptors. 2015 J. Biol. Chem. pmid:26468289
Cole SP Multidrug resistance protein 1 (MRP1, ABCC1), a "multitasking" ATP-binding cassette (ABC) transporter. 2014 J. Biol. Chem. pmid:25281745
Mao Q et al. Functional reconstitution of substrate transport by purified multidrug resistance protein MRP1 (ABCC1) in phospholipid vesicles. 2000 J. Biol. Chem. pmid:10942765
Stride BD et al. Localization of a substrate specificity domain in the multidrug resistance protein. 1999 J. Biol. Chem. pmid:10428874
Heise CE et al. Characterization of the human cysteinyl leukotriene 2 receptor. 2000 J. Biol. Chem. pmid:10851239
Conseil G et al. Functional importance of three basic residues clustered at the cytosolic interface of transmembrane helix 15 in the multidrug and organic anion transporter MRP1 (ABCC1). 2006 J. Biol. Chem. pmid:16230346
Bowers RC et al. A novel glutathione containing eicosanoid (FOG7) chemotactic for human granulocytes. 2000 J. Biol. Chem. pmid:10924496
Ito K et al. Functional analysis of a canalicular multispecific organic anion transporter cloned from rat liver. 1998 J. Biol. Chem. pmid:9430713
Westlake CJ et al. Identification and characterization of functionally important elements in the multidrug resistance protein 1 COOH-terminal region. 2004 J. Biol. Chem. pmid:15459206
Bakos E et al. Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain. 1998 J. Biol. Chem. pmid:9822694
Christmas P et al. Membrane localization and topology of leukotriene C4 synthase. 2002 J. Biol. Chem. pmid:12023288
Hui Y et al. The murine cysteinyl leukotriene 2 (CysLT2) receptor. cDNA and genomic cloning, alternative splicing, and in vitro characterization. 2001 J. Biol. Chem. pmid:11591709
Hong JT et al. Effect of phenobarbital and the peroxisome proliferator ciprofibrate on gamma-Glutamyltranspeptidase activity and leukotriene C4 concentration in cultured rat hepatocytes. 1995 J. Biochem. Toxicol. pmid:8847705
Ren XQ et al. A functional role of intracellular loops of human multidrug resistance protein 1. 2006 J. Biochem. pmid:16861249
Falcón-Pérez JM et al. Domain interactions in the yeast ATP binding cassette transporter Ycf1p: intragenic suppressor analysis of mutations in the nucleotide binding domains. 2001 J. Bacteriol. pmid:11466279
De Castro CM et al. Modulation by dexamethasone of phospholipase A2 activities in endotoxemic guinea pigs. 1995 J. Appl. Physiol. pmid:8567572
Hevko JM and Murphy RC Electrospray ionization and tandem mass spectrometry of cysteinyl eicosanoids: leukotriene C4 and FOG7. 2001 J. Am. Soc. Mass Spectrom. pmid:11444597
Devakumar A et al. Structural analysis of leukotriene C4 isomers using collisional activation and 157 nm photodissociation. 2008 J. Am. Soc. Mass Spectrom. pmid:18024058
De Servi S et al. Transcardiac release of leukotriene C4 by neutrophils in patients with coronary artery disease. 1991 J. Am. Coll. Cardiol. pmid:2007712
Olynych TJ et al. Fungal zymosan induces leukotriene production by human mast cells through a dectin-1-dependent mechanism. 2006 J. Allergy Clin. Immunol. pmid:17030235
Nakasato H et al. Prevention of severe premenstrual asthma attacks by leukotriene receptor antagonist. 1999 J. Allergy Clin. Immunol. pmid:10482831
Sachs-Olsen C et al. Eoxins: a new inflammatory pathway in childhood asthma. 2010 J. Allergy Clin. Immunol. pmid:20920774
Akin C et al. Mast cell activation syndrome: Proposed diagnostic criteria. 2010 J. Allergy Clin. Immunol. pmid:21035176
Thivierge M et al. Toll-like receptor agonists differentially regulate cysteinyl-leukotriene receptor 1 expression and function in human dendritic cells. 2006 J. Allergy Clin. Immunol. pmid:16675346
Zaitsu M et al. A novel pharmacologic action of glucocorticosteroids on leukotriene C4 catabolism. 2001 J. Allergy Clin. Immunol. pmid:11447392
Lee TH et al. Leukotriene E4: perspective on the forgotten mediator. 2009 J. Allergy Clin. Immunol. pmid:19482346
Austen KF et al. The leukotriene E4 puzzle: finding the missing pieces and revealing the pathobiologic implications. 2009 J. Allergy Clin. Immunol. pmid:19647860
Chen YH et al. IFN-alpha inhibits IL-3 priming of human basophil cytokine secretion but not leukotriene C4 and histamine release. 2003 J. Allergy Clin. Immunol. pmid:14610485
Horsmanheimo L et al. Histamine and leukotriene C4 release in cutaneous mosquito-bite reactions. 1996 J. Allergy Clin. Immunol. pmid:8757218
de Paulis A et al. Cyclosporin H is a potent and selective competitive antagonist of human basophil activation by N-formyl-methionyl-leucyl-phenylalanine. 1996 J. Allergy Clin. Immunol. pmid:8765829
Macglashan DW and Saini SS Omalizumab increases the intrinsic sensitivity of human basophils to IgE-mediated stimulation. 2013 J. Allergy Clin. Immunol. pmid:23791510
Kowalski ML et al. Differential effects of aspirin and misoprostol on 15-hydroxyeicosatetraenoic acid generation by leukocytes from aspirin-sensitive asthmatic patients. 2003 J. Allergy Clin. Immunol. pmid:13679808
Juergens UR et al. Inhibition of monocyte leukotriene B4 production after aspirin desensitization. 1995 J. Allergy Clin. Immunol. pmid:7636051
Zweiman B et al. Nasal airway changes assessed by acoustic rhinometry and mediator release during immediate and late reactions to allergen challenge. 1997 J. Allergy Clin. Immunol. pmid:9389292