Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.
To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with LTC4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Marquardt DL et al. | Mast cell desensitization to IgE fails to induce a parallel adenosine receptor desensitization. | 1993 | Agents Actions | pmid:8147265 |
Sirois MG et al. | Platelet activating factor modulates peptidoleukotriene effects on the permeability of bovine aortic endothelial cell to albumin. | 1993 | Agents Actions | pmid:8273559 |
Rainsford KD | Leukotrienes in the pathogenesis of NSAID-induced gastric and intestinal mucosal damage. | 1993 | Agents Actions | pmid:8273575 |
Butenko IG et al. | Anti-inflammatory properties and inhibition of leukotriene C4 biosynthesis in vitro by flavonoid baicalein from Scutellaria baicalensis georgy roots. | 1993 | Agents Actions | pmid:8273583 |
Ramachers U et al. | Direct effects of second-generation H1-receptor antagonists on the activation of human basophils. | 1994 | Agents Actions | pmid:7526656 |
Amon U et al. | Control function of protein kinase C isozymes on leukotriene generation from human basophils? | 1994 | Agents Actions | pmid:7976816 |
Florio G et al. | The immunoglobulin superantigen-binding site of HIV-1 gp120 activates human basophils. | 2000 | AIDS | pmid:10853974 |
Sabbah A et al. | [Anaphylactic or anaphylactoid reactions to paracetamol. Report of 3 cases]. | 1997 | Allerg Immunol (Paris) | pmid:9221011 |
Sabbah A et al. | [Testing basophil activation by flow cytometry in the diagnosis of allergy to hymenopteran venom]. | 1998 | Allerg Immunol (Paris) | pmid:9559061 |
Collin N et al. | [Search for a threshold to distinguish between locoregional and systemic reactions using the histamine liberation value and the LTC4 level]. | 1999 | Allerg Immunol (Paris) | pmid:10070593 |