LTC4
Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.
Cross Reference
Introduction
To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with LTC4?
LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with LTC4
PubChem Associated disorders and diseases
What pathways are associated with LTC4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with LTC4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with LTC4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with LTC4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with LTC4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with LTC4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with LTC4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Hisamatsu K et al. | Effect of leukotriene C4 exposure on ciliated cells of the nasal mucosa. | 1996 | Prostaglandins | pmid:8900445 |
| Gao M et al. | Reconstitution of ATP-dependent leukotriene C4 transport by Co-expression of both half-molecules of human multidrug resistance protein in insect cells. | 1996 | J. Biol. Chem. | pmid:8910374 |
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| Jutel M et al. | Influence of bee venom immunotherapy on degranulation and leukotriene generation in human blood basophils. | 1996 | Clin. Exp. Allergy | pmid:8911695 |
| Omar HM et al. | Hepatobiliary excretion of cysteinyl leukotrienes in three experimental models of acute hepatic injury. | 1996 | Inflamm. Res. | pmid:8912018 |
| Müller D et al. | Bile ductular proliferation and altered leukotriene elimination in thioacetamide-induced fibrosis of rat liver. | 1996 | J. Hepatol. | pmid:8912155 |
| Sedgwick JB et al. | Effect of isolation protocol on eosinophil function: Percoll gradients versus immunomagnetic beads. | 1996 | J. Immunol. Methods | pmid:8914593 |
| Burghardt JS et al. | Lipid mediators in oxygen-induced airway remodeling and hyperresponsiveness in newborn rats. | 1996 | Am. J. Respir. Crit. Care Med. | pmid:8887572 |
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| de Paulis A et al. | Human synovial mast cells. I. Ultrastructural in situ and in vitro immunologic characterization. | 1996 | Arthritis Rheum. | pmid:8670335 |
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| Campbell A et al. | Overview of allergic mechanisms. Ebastine has more than an antihistamine effect. | 1996 | Drugs | pmid:8983912 |
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| Kang BC et al. | Experimental asthma developed by room air contamination with cockroach allergen. | 1996 | Int. Arch. Allergy Immunol. | pmid:8917126 |
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| Funayama T et al. | Role of Leukotriene-degrading enzymes in pulmonary response to antigen infusion in sensitized guinea pigs in vivo. | 1996 | Am. J. Respir. Cell Mol. Biol. | pmid:8703483 |
| Güllüoğlu BM et al. | Endothelin release is augmented with captopril in rat ischemia-reperfusion injury of the liver. | 1996 | Res Exp Med (Berl) | pmid:8903098 |
| Nishisho T et al. | Experimental and clinical studies of eicosanoids in cerebrospinal fluid after spinal cord injury. | 1996 | Neurosurgery | pmid:8905750 |
| Breil I et al. | Alteration of n-3 fatty acid composition in lung tissue after short-term infusion of fish oil emulsion attenuates inflammatory vascular reaction. | 1996 | Crit. Care Med. | pmid:8917042 |
| Muñoz NM et al. | Eosinophil VLA-4 binding to fibronectin augments bronchial narrowing through 5-lipoxygenase activation. | 1996 | Am. J. Physiol. | pmid:8928818 |
| Paul S et al. | Structure and in vitro substrate specificity of the murine multidrug resistance-associated protein. | 1996 | Biochemistry | pmid:8885844 |
| Tenor H et al. | Effects of theophylline and rolipram on leukotriene C4 (LTC4) synthesis and chemotaxis of human eosinophils from normal and atopic subjects. | 1996 | Br. J. Pharmacol. | pmid:8842438 |
| Richter L et al. | Increased biliary secretion of cysteinyl-leukotrienes in human bile duct obstruction. | 1996 | J. Hepatol. | pmid:8938552 |
| Sun H et al. | Expression and characterization of the multidrug resistance-associated protein in insect cells infected with a recombinant baculovirus. | 1996 | Oncol. Res. | pmid:8938792 |
| Lane SJ and Lee TH | Mast cell effector mechanisms. | 1996 | J. Allergy Clin. Immunol. | pmid:8939179 |