| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Osteosarcoma | D012516 | 50 associated lipids |
| Coronary Artery Disease | D003324 | 47 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Ischemic Attack, Transient | D002546 | 42 associated lipids |
LTC4
Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.
Cross Reference
Introduction
To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with LTC4?
LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with LTC4
PubChem Associated disorders and diseases
What pathways are associated with LTC4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with LTC4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with LTC4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with LTC4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with LTC4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with LTC4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with LTC4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lai YL and Lin TY | Mast cells in citric acid-induced cough of guinea pigs. | 2005 | Toxicol. Appl. Pharmacol. | pmid:15589973 |
| Weide I et al. | Intravascular cysteinyl-leukotriene formation by clotting whole human blood. Evidence from clamped umbilical vein segments and thrombus specimens. | 1993 | Thromb. Res. | pmid:8122190 |
| Shindo K et al. | Priming effect of platelet activating factor on leukotriene C4 from stimulated eosinophils of asthmatic patients. | 1996 | Thorax | pmid:8711647 |
| Lee TH and Christie PE | Leukotrienes and aspirin induced asthma. | 1993 | Thorax | pmid:8303620 |
| Dahlén B et al. | Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects. | 1993 | Thorax | pmid:8303624 |
| Restrick LJ et al. | Reduction in leukotriene B4 generation by bronchoalveolar lavage cells in asthma. | 1995 | Thorax | pmid:7886653 |
| Randolph GJ et al. | Factors and signals that govern the migration of dendritic cells via lymphatics: recent advances. | 2005 | Springer Semin. Immunopathol. | pmid:15338191 |
| Akpek EA et al. | A study of adenosine treatment in experimental acute spinal cord injury. Effect on arachidonic acid metabolites. | 1999 | Spine | pmid:9926381 |
| Willburger RE and Wittenberg RH | Prostaglandin release from lumbar disc and facet joint tissue. | 1994 | Spine | pmid:7825047 |
| Chen X et al. | [Preventive effects of montelukast on hypoxic pulmonary hypertension in rats]. | 2003 | Sichuan Da Xue Xue Bao Yi Xue Ban | pmid:12910720 |