| MeSH term | MeSH ID | Detail |
|---|---|---|
| Mesenteric Vascular Occlusion | D008641 | 4 associated lipids |
| Eosinophilia | D004802 | 4 associated lipids |
| Insect Bites and Stings | D007299 | 4 associated lipids |
| Rhinitis, Allergic, Perennial | D012221 | 6 associated lipids |
| Periapical Periodontitis | D010485 | 6 associated lipids |
| Ear Diseases | D004427 | 7 associated lipids |
| Rhinitis, Allergic, Seasonal | D006255 | 7 associated lipids |
| Cholestasis, Extrahepatic | D001651 | 7 associated lipids |
| Pneumococcal Infections | D011008 | 7 associated lipids |
| Asbestosis | D001195 | 8 associated lipids |
LTC4
Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.
Cross Reference
Introduction
To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with LTC4?
LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with LTC4
PubChem Associated disorders and diseases
What pathways are associated with LTC4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with LTC4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with LTC4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with LTC4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with LTC4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with LTC4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with LTC4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Munoz NM et al. | Beta adrenergic modulation of formyl-methionine-leucine-phenylalanine-stimulated secretion of eosinophil peroxidase and leukotriene C4. | 1994 | J. Pharmacol. Exp. Ther. | pmid:8301549 |
| Sathirakul K et al. | Multiple transport systems for organic anions across the bile canalicular membrane. | 1994 | J. Pharmacol. Exp. Ther. | pmid:8301595 |
| Metters KM et al. | Microsomal glutathione S-transferase is the predominant leukotriene C4 binding site in cellular membranes. | 1994 | J. Biol. Chem. | pmid:8175695 |
| Kargman S et al. | Protein kinase C-dependent regulation of sulfidopeptide leukotriene biosynthesis and leukotriene C4 synthase in neutrophilic HL-60 cells. | 1994 | Mol. Pharmacol. | pmid:8190095 |
| Willburger RE and Wittenberg RH | Prostaglandin release from lumbar disc and facet joint tissue. | 1994 | Spine | pmid:7825047 |
| Wang D et al. | Concentrations of chemical mediators in nasal secretions of patients with hay fever during natural allergen exposure. | 1994 | Acta Otolaryngol. | pmid:7825440 |
| Hamasaki Y et al. | Inhibition by dexamethasone of retinoic acid-induced enhancement of leukotriene C4 synthesis in rat basophilic leukemia-1 cells. | 1994 | Am. J. Respir. Cell Mol. Biol. | pmid:8018338 |
| Aktan AO et al. | Does PGE2 act as a mediator for endothelin release? | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7511821 |
| YeÄŸen C et al. | Effect of verapamil and iloprost (ZK 36374) on endothelin release after mesenteric ischemia-reperfusion injury. | 1994 | Eur Surg Res | pmid:7516292 |
| Thioudellet C et al. | Molecular and functional characterization of recombinant human gamma-glutamyltransferase. Coupling of its activity to glutathione levels in V79 cells. | 1994 | Eur. J. Biochem. | pmid:7913033 |