LTC4

Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.

Cross Reference

Introduction

To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with LTC4?

LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with LTC4

MeSH term MeSH ID Detail
Mesenteric Vascular Occlusion D008641 4 associated lipids
Eosinophilia D004802 4 associated lipids
Insect Bites and Stings D007299 4 associated lipids
Rhinitis, Allergic, Perennial D012221 6 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Ear Diseases D004427 7 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Pneumococcal Infections D011008 7 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Asbestosis D001195 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with LTC4

Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with LTC4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with LTC4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with LTC4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with LTC4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with LTC4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with LTC4

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Authors Title Published Journal PubMed Link
Tudhope SR et al. BAY u9773, a novel antagonist of cysteinyl-leukotrienes with activity against two receptor subtypes. 1994 Eur. J. Pharmacol. pmid:7698171
Bürgi B et al. The degradation product of the C5a anaphylatoxin C5adesarg retains basophil-activating properties. 1994 Eur. J. Immunol. pmid:7517876
Sainte-Laudy J et al. [Demonstration of sulfite-group-specific IgE in patients with intolerance to preservatives]. 1994 Allerg Immunol (Paris) pmid:7518236
Miadonna A et al. Modulation of allergen-induced nasal symptoms and mediator release by treatment with N-acetyl-aspartyl-glutamate (ZY15106). 1994 Eur. J. Clin. Pharmacol. pmid:7518775
Yamamura H et al. Endothelin-1 induces release of histamine and leukotriene C4 from mouse bone marrow-derived mast cells. 1994 Eur. J. Pharmacol. pmid:7522171
Ohemeng KA et al. Novel bishydroxamic acids as 5-lipoxygenase inhibitors. 1994 Bioorg. Med. Chem. pmid:7922131
Busse WW and Sedgwick JB Eosinophil eicosanoid relations in allergic inflammation of the airways. 1994 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:7771338
Gardiner PJ et al. Leukotriene receptors and their selective antagonists. 1994 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:7771349
Keppler D et al. Transport and metabolism of leukotrienes. 1994 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:7771352
Laviolette M et al. Effects of inhaled steroids on blood eosinophils in moderate asthma. 1994 Ann. N. Y. Acad. Sci. pmid:8031001