LTC4

Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.

Cross Reference

Introduction

To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with LTC4?

LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with LTC4

MeSH term MeSH ID Detail
Picornaviridae Infections D010850 4 associated lipids
Status Asthmaticus D013224 4 associated lipids
Wounds, Nonpenetrating D014949 4 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Rhinitis, Allergic, Perennial D012221 6 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Pneumococcal Infections D011008 7 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Ear Diseases D004427 7 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with LTC4

Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with LTC4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with LTC4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with LTC4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with LTC4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with LTC4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with LTC4

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Authors Title Published Journal PubMed Link
Takase B et al. Effects of bepridil on silent myocardial ischemia and eicosanoid metabolism in chronic stable angina pectoris after healing of myocardial infarction. 1994 Am. J. Cardiol. pmid:8198031
Zuany-Amorim C et al. Strain-dependency of leukotriene C4 generation from isolated lungs of immunized mice. 1994 Br. J. Pharmacol. pmid:7524994
Kawashima T et al. Inhibitory effect of pemirolast, a novel antiallergic drug, on leukotriene C4 and granule protein release from human eosinophils. 1994 Int. Arch. Allergy Immunol. pmid:8130655
Fiore S et al. Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptor. 1994 J. Exp. Med. pmid:8006586
Böhme M et al. ATP-dependent export pumps and their inhibition by cyclosporins. 1994 Adv. Enzyme Regul. pmid:7942282
Kurosawa M et al. Inhibition by a novel peptide leukotriene receptor antagonist ONO-1078 of airway wall thickening and airway hyperresponsiveness to histamine induced by leukotriene C4 or leukotriene D4 in guinea-pigs. 1994 Clin. Exp. Allergy pmid:7842366
Christie PE et al. Increased urinary LTE4 excretion following inhalation of LTC4 and LTE4 in asthmatic subjects. 1994 Eur. Respir. J. pmid:8050548
Ramis I et al. Application of totally automated on-line sample clean up system for extraction and high-performance liquid chromatography separation of peptide leukotrienes. 1993 Nov-Dec J Pharm Biomed Anal pmid:8123725
Sichletidis L et al. Comparative efficacy of salbutamol and salmeterol in exercise-induced asthma. 1993 Mar-Apr J. Int. Med. Res. pmid:8243793
MacGlashan DW and Hubbard WC IL-3 alters free arachidonic acid generation in C5a-stimulated human basophils. 1993 J. Immunol. pmid:8245471