LTC4

Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.

Cross Reference

Introduction

To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with LTC4?

LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with LTC4

MeSH term MeSH ID Detail
Eosinophilia D004802 4 associated lipids
Status Asthmaticus D013224 4 associated lipids
Wounds, Nonpenetrating D014949 4 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Rhinitis, Allergic, Perennial D012221 6 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Pneumococcal Infections D011008 7 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Ear Diseases D004427 7 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with LTC4

Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with LTC4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with LTC4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with LTC4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with LTC4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with LTC4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with LTC4

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Authors Title Published Journal PubMed Link
Diven WF et al. Expression of acute otitis media after receptor blockade of platelet activating factor, thromboxane, and leukotrienes in the chinchilla. 1998 Ann. Otol. Rhinol. Laryngol. pmid:9525240
Black P et al. Chemotherapy in experimental brain tumor, part 2: pretreatment with leukotriene C4 prolongs survival. 1998 J. Neurooncol. pmid:9525821
Capra V et al. Identification and characterization of two cysteinyl-leukotriene high affinity binding sites with receptor characteristics in human lung parenchyma. 1998 Mol. Pharmacol. pmid:9547367
Brady HR et al. Transcellular pathways and cell adhesion as potential contributors to leukotriene and lipoxin biosynthesis in acute glomerulonephritis. 1997 Adv. Exp. Med. Biol. pmid:9547614
Sperber K et al. Mucin secretion in inflammatory bowel disease: comparison of a macrophage-derived mucin secretagogue (MMS-68) to conventional secretagogues. 1998 Inflamm. Bowel Dis. pmid:9552223
Gao M et al. Multidrug resistance protein. Identification of regions required for active transport of leukotriene C4. 1998 J. Biol. Chem. pmid:9553138
Scheidegger C et al. Effects of extracts and of individual components from Petasites on prostaglandin synthesis in cultured skin fibroblasts and on leucotriene synthesis in isolated human peripheral leucocytes. 1998 Pharm Acta Helv pmid:9556438
Sabbah A et al. [Testing basophil activation by flow cytometry in the diagnosis of allergy to hymenopteran venom]. 1998 Allerg Immunol (Paris) pmid:9559061
Cyrus CB et al. Leukotrienes C4 and D4 increase the ciliary beat frequency in human upper airway mucosa in vitro. 1998 Otolaryngol Head Neck Surg pmid:9560097
Herman CA et al. Synthesis and action of eicosanoids in warm and cold-acclimated amphibians. 1997 Adv. Exp. Med. Biol. pmid:9561172