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Molecular modeling correctly predicts the functional importance of Phe594 in transmembrane helix 11 of the multidrug resistance protein, MRP1 (ABCC1). |
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J. Biol. Chem. |
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Mutation of the aromatic amino acid interacting with adenine moiety of ATP to a polar residue alters the properties of multidrug resistance protein 1. |
2004 |
J. Biol. Chem. |
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The FcepsilonRIbeta immunoreceptor tyrosine-based activation motif exerts inhibitory control on MAPK and IkappaB kinase phosphorylation and mast cell cytokine production. |
2004 |
J. Biol. Chem. |
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MITF is necessary for generation of prostaglandin D2 in mouse mast cells. |
2004 |
J. Biol. Chem. |
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Ito R et al. |
[Effect of pranlukast on histamine release and leukotriene c4 (ltc4) generation from human peripheral basophils]. |
2004 |
Arerugi |
pmid:14762327
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Directed vascular expression of human cysteinyl leukotriene 2 receptor modulates endothelial permeability and systemic blood pressure. |
2004 |
Circulation |
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Lam BK |
Leukotriene C(4) synthase. |
2003 Aug-Sep |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12895593
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Bandeira-Melo C and Weller PF |
Eosinophils and cysteinyl leukotrienes. |
2003 Aug-Sep |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12895596
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Genovese A et al. |
Protein Fv produced during viral hepatitis is an endogenous immunoglobulin superantigen activating human heart mast cells. |
2003 |
Int. Arch. Allergy Immunol. |
pmid:14707465
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Vargaftig BB and Singer M |
Leukotrienes mediate part of Ova-induced lung effects in mice via EGFR. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12794006
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Chen YH et al. |
IFN-alpha inhibits IL-3 priming of human basophil cytokine secretion but not leukotriene C4 and histamine release. |
2003 |
J. Allergy Clin. Immunol. |
pmid:14610485
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Neuroimmune interactions in guinea pig stomach and small intestine. |
2003 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:12388180
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Effects of n-3 polyunsaturated fatty acids on indomethacin-induced changes in eicosanoid production and blood flow in the gastric mucosa of rats. |
2003 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12878448
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Oleschuk CJ et al. |
Substitution of Trp1242 of TM17 alters substrate specificity of human multidrug resistance protein 3. |
2003 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:12388190
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Schuhmann MU et al. |
Temporal profiles of cerebrospinal fluid leukotrienes, brain edema and inflammatory response following experimental brain injury. |
2003 |
Neurol. Res. |
pmid:12866196
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Roles of tumor necrosis factor-alpha of the estrous cycle in cattle: an in vivo study. |
2003 |
Biol. Reprod. |
pmid:12904309
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Muñoz NM et al. |
Human group V phospholipase A2 induces group IVA phospholipase A2-independent cysteinyl leukotriene synthesis in human eosinophils. |
2003 |
J. Biol. Chem. |
pmid:12796497
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Endothelial cells modulate eosinophil surface markers and mediator release. |
2003 |
Eur. Respir. J. |
pmid:12797482
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Bronchial mast cells are the dominating LTC4S-expressing cells in aspirin-tolerant asthma. |
2003 |
Am. J. Respir. Cell Mol. Biol. |
pmid:12816731
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Miller LA et al. |
Glutathione, S-substituted glutathiones, and leukotriene C4 as substrates for peptidylglycine alpha-amidating monooxygenase. |
2003 |
Arch. Biochem. Biophys. |
pmid:12646261
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Strait RT et al. |
IL-4 exacerbates anaphylaxis. |
2003 |
J. Immunol. |
pmid:12646651
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Bestatin selectively suppresses the growth of leukemic stem/progenitor cells with BCR/ABL mRNA transcript in patients with chronic myelogeneous leukemia. |
2003 |
Int. Immunopharmacol. |
pmid:12781706
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Arumugam TV et al. |
Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonist. |
2003 |
Br. J. Pharmacol. |
pmid:12967936
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Zhang DW et al. |
Functional importance of polar and charged amino acid residues in transmembrane helix 14 of multidrug resistance protein 1 (MRP1/ABCC1): identification of an aspartate residue critical for conversion from a high to low affinity substrate binding state. |
2003 |
J. Biol. Chem. |
pmid:12954620
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Kowalski ML et al. |
Differential effects of aspirin and misoprostol on 15-hydroxyeicosatetraenoic acid generation by leukocytes from aspirin-sensitive asthmatic patients. |
2003 |
J. Allergy Clin. Immunol. |
pmid:13679808
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Cloning and functional characterization of the multidrug resistance-associated protein (MRP1/ABCC1) from the cynomolgus monkey. |
2003 |
Mol. Cancer Ther. |
pmid:12657726
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The organization and consequences of eicosanoid signaling. |
2003 |
J. Clin. Invest. |
pmid:12697726
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Carboxypeptidase A-catalyzed direct conversion of leukotriene C4 to leukotriene F4. |
2003 |
Arch. Biochem. Biophys. |
pmid:12729612
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Identification of domains participating in the substrate specificity and subcellular localization of the multidrug resistance proteins MRP1 and MRP2. |
2003 |
J. Biol. Chem. |
pmid:12682044
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Up-regulation of cysteinyl leukotriene 1 receptor by IL-13 enables human lung fibroblasts to respond to leukotriene C4 and produce eotaxin. |
2003 |
J. Immunol. |
pmid:12682264
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Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1). |
2003 |
Biochemistry |
pmid:12731862
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LTC4 production by eosinophils in asthmatic subjects with alternative forms of ALOX-5 core promoter. |
2003 |
Adv. Exp. Med. Biol. |
pmid:12751728
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Lipopolysaccharide down-regulates the leukotriene C4 synthase gene in the monocyte-like cell line, THP-1. |
2003 |
J. Immunol. |
pmid:12574384
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Wang DY et al. |
The upper and lower airway responses to nasal challenge with house-dust mite Blomia tropicalis. |
2003 |
Allergy |
pmid:12580812
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Bellou A et al. |
Constitutive nitric oxide synthase inhibition combined with histamine and serotonin receptor blockade improves the initial ovalbumin-induced arterial hypotension but decreases the survival time in brown norway rats anaphylactic shock. |
2003 |
Shock |
pmid:12558148
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Söderström M et al. |
Expression of leukotriene C4 synthase mRNA by the choroid plexus in mouse brain suggests novel neurohormone functions of cysteinyl leukotrienes. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12878209
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Zaitsu M et al. |
Dexamethasone accelerates catabolism of leukotriene C4 in bronchial epithelial cells. |
2003 |
Eur. Respir. J. |
pmid:12882448
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Blockade of LTC4 synthesis caused by additive inhibition of gIV-PLA2 phosphorylation: Effect of salmeterol and PDE4 inhibition in human eosinophils. |
2003 |
J. Allergy Clin. Immunol. |
pmid:12897749
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[Preventive effects of montelukast on hypoxic pulmonary hypertension in rats]. |
2003 |
Sichuan Da Xue Xue Bao Yi Xue Ban |
pmid:12910720
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Lie WJ et al. |
Regulation and kinetics of platelet-activating factor and leukotriene C4 synthesis by activated human basophils. |
2003 |
Clin. Exp. Allergy |
pmid:12911788
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Moloney ED et al. |
Release of inflammatory mediators from eosinophils following a hyperosmolar stimulus. |
2003 |
Respir Med |
pmid:12924520
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Zhang DW et al. |
Characterization of the role of polar amino acid residues within predicted transmembrane helix 17 in determining the substrate specificity of multidrug resistance protein 3. |
2003 |
Biochemistry |
pmid:12924948
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Payen LF et al. |
Role of carboxylate residues adjacent to the conserved core Walker B motifs in the catalytic cycle of multidrug resistance protein 1 (ABCC1). |
2003 |
J. Biol. Chem. |
pmid:12882957
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Molecular cloning and pharmacological characterization of rat multidrug resistance protein 1 (mrp1). |
2003 |
Drug Metab. Dispos. |
pmid:12867490
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Tanaka H et al. |
Biliary excretion of phenolphthalein sulfate in rats. |
2003 |
Pharmacology |
pmid:12837971
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Ichiyama T et al. |
Pranlukast inhibits NF-kappa B activation in human monocytes/macrophages and T cells. |
2003 |
Clin. Exp. Allergy |
pmid:12801316
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Mizutani N |
[Studies on the experimental allergic rhinitis induced by Japanese cedar pollen--role of cysteinyl leukotrienes in nasal allergic symptoms]. |
2003 |
Yakugaku Zasshi |
pmid:12607939
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Mechiche H et al. |
Effects of cysteinyl leukotrienes in small human bronchus and antagonist activity of montelukast and its metabolites. |
2003 |
Clin. Exp. Allergy |
pmid:12859443
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Nagase T et al. |
A potent inhibitor of cytosolic phospholipase A2, arachidonyl trifluoromethyl ketone, attenuates LPS-induced lung injury in mice. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12505870
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Vargaftig BB and Singer M |
Leukotrienes, IL-13, and chemokines cooperate to induce BHR and mucus in allergic mouse lungs. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12388339
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