LTC4

Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.

Cross Reference

Introduction

To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with LTC4?

LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with LTC4

MeSH term MeSH ID Detail
Asbestosis D001195 8 associated lipids
Respiratory Syncytial Virus Infections D018357 10 associated lipids
Asthma, Exercise-Induced D001250 10 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Myocardial Ischemia D017202 11 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Acute-Phase Reaction D000210 12 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Airway Obstruction D000402 13 associated lipids
Uveitis D014605 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with LTC4

Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with LTC4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with LTC4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with LTC4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with LTC4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with LTC4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with LTC4

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Authors Title Published Journal PubMed Link
Willburger RE and Wittenberg RH Prostaglandin release from lumbar disc and facet joint tissue. 1994 Spine pmid:7825047
Wang D et al. Concentrations of chemical mediators in nasal secretions of patients with hay fever during natural allergen exposure. 1994 Acta Otolaryngol. pmid:7825440
Hamasaki Y et al. Inhibition by dexamethasone of retinoic acid-induced enhancement of leukotriene C4 synthesis in rat basophilic leukemia-1 cells. 1994 Am. J. Respir. Cell Mol. Biol. pmid:8018338
Miadonna A et al. Modulation of allergen-induced nasal symptoms and mediator release by treatment with N-acetyl-aspartyl-glutamate (ZY15106). 1994 Eur. J. Clin. Pharmacol. pmid:7518775
Yamamura H et al. Endothelin-1 induces release of histamine and leukotriene C4 from mouse bone marrow-derived mast cells. 1994 Eur. J. Pharmacol. pmid:7522171
Shimizu T et al. Inhibitory effects of theophylline, terbutaline, and hydrocortisone on leukotriene B4 and C4 generation by human leukocytes in vitro. 1994 Pediatr. Pulmonol. pmid:7800427
Busse WW and Sedgwick JB Eosinophil eicosanoid relations in allergic inflammation of the airways. 1994 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:7771338
Gardiner PJ et al. Leukotriene receptors and their selective antagonists. 1994 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:7771349
Keppler D et al. Transport and metabolism of leukotrienes. 1994 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:7771352
Laviolette M et al. Effects of inhaled steroids on blood eosinophils in moderate asthma. 1994 Ann. N. Y. Acad. Sci. pmid:8031001