LTC4

Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.

Cross Reference

Introduction

To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with LTC4?

LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with LTC4

MeSH term MeSH ID Detail
Carotid Artery Injuries D020212 8 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Respiratory Syncytial Virus Infections D018357 10 associated lipids
Asthma, Exercise-Induced D001250 10 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Myocardial Ischemia D017202 11 associated lipids
Acute-Phase Reaction D000210 12 associated lipids
Airway Obstruction D000402 13 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Uveitis D014605 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with LTC4

Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with LTC4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with LTC4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with LTC4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with LTC4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with LTC4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with LTC4

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Authors Title Published Journal PubMed Link
Le Poole IC et al. Organotypic culture of human skin to study melanocyte migration. 1994 Pigment Cell Res. pmid:8072944
Currie S et al. Phosphorylation and activation of Ca(2+)-sensitive cytosolic phospholipase A2 in MCII mast cells mediated by high-affinity Fc receptor for IgE. 1994 Biochem. J. pmid:7818499
Leier I et al. Characterization of the ATP-dependent leukotriene C4 export carrier in mastocytoma cells. 1994 Eur. J. Biochem. pmid:8125120
O'Neil GS et al. Effect of surgical preparation and arterialization on vasomotion of human saphenous vein. 1994 J. Thorac. Cardiovasc. Surg. pmid:8127099
Myers SI and Hernandez R Leukotriene C4 regulation of splanchnic blood flow during ischemia. 1994 Am. J. Surg. pmid:8209929
Büyükgebiz O et al. Captopril increases endothelin serum concentrations and preserves intestinal mucosa after mesenteric ischemia-reperfusion injury. 1994 Res Exp Med (Berl) pmid:7536337
Petric R and Ford-Hutchinson AW Elevated cysteinyl leukotriene excretion in experimental glomerulonephritis. 1994 Kidney Int. pmid:7853790
Leier I et al. The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates. 1994 J. Biol. Chem. pmid:7961706
Scadding GK et al. Effect of short-term treatment with fluticasone propionate nasal spray on the response to nasal allergen challenge. 1994 Br J Clin Pharmacol pmid:7893587
Ishii K et al. A useful method for differential evaluation of anti-inflammatory effects due to cyclooxygenase and 5-lipoxygenase inhibitions in mice. 1994 Jpn. J. Pharmacol. pmid:7990266