| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carotid Artery Injuries | D020212 | 8 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
| Asthma, Exercise-Induced | D001250 | 10 associated lipids |
| Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
| Myocardial Ischemia | D017202 | 11 associated lipids |
| Hyperbilirubinemia | D006932 | 11 associated lipids |
| Acute-Phase Reaction | D000210 | 12 associated lipids |
| Airway Obstruction | D000402 | 13 associated lipids |
| Abnormalities, Multiple | D000015 | 13 associated lipids |
| Uveitis | D014605 | 14 associated lipids |
LTC4
Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.
Cross Reference
Introduction
To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with LTC4?
LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with LTC4
PubChem Associated disorders and diseases
What pathways are associated with LTC4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with LTC4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with LTC4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with LTC4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with LTC4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with LTC4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with LTC4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rainsford KD | Leukotrienes in the pathogenesis of NSAID-induced gastric and intestinal mucosal damage. | 1993 | Agents Actions | pmid:8273575 |
| Butenko IG et al. | Anti-inflammatory properties and inhibition of leukotriene C4 biosynthesis in vitro by flavonoid baicalein from Scutellaria baicalensis georgy roots. | 1993 | Agents Actions | pmid:8273583 |
| Herman CA et al. | Metabolism and cardiovascular effects of leukotrienes in the marine toad Bufo marinus. | 1993 | Gen. Comp. Endocrinol. | pmid:8262353 |
| Sala A et al. | Formation of sulphidopeptide-leukotrienes by cell-cell interaction causes coronary vasoconstriction in isolated, cell-perfused heart of rabbit. | 1993 | Br. J. Pharmacol. | pmid:8298810 |
| Wallis RA and Panizzon KL | Protection from hypoxic and N-methyl-D-aspartate injury with azelastine, a leukotriene inhibitor. | 1993 | Eur. J. Pharmacol. | pmid:8405089 |
| Katori M et al. | Interaction of substance P and leukotriene C4 in ethanol-induced mucosal injury of rat stomach. | 1993 | Regul. Pept. | pmid:7692504 |
| Patella V et al. | Protein Fv produced during vital hepatitis is a novel activator of human basophils and mast cells. | 1993 | J. Immunol. | pmid:7693815 |
| Huber W et al. | Leukotriene B4 and C4 production in isolated rat gastric mucosal cells. | 1993 | Am. J. Physiol. | pmid:8279553 |
| Sawyer MM et al. | Arachidonic acid immunoregulation in lambs persistently infected with border disease virus. | 1993 | Comp. Immunol. Microbiol. Infect. Dis. | pmid:8281741 |
| Renić M et al. | The effect of interleukin 1 alpha on acetaminophen-induced hepatotoxicity. | 1993 | Cytokine | pmid:8218930 |
| Kohrogi H et al. | Release of tachykinins and its metabolism in the airway. | 1993 | Regul. Pept. | pmid:8210488 |
| Devalia JL et al. | Human bronchial epithelial cell dysfunction following in vitro exposure to nitrogen dioxide. | 1993 | Eur. Respir. J. | pmid:8287947 |
| MacGlashan DW and Hubbard WC | IL-3 alters free arachidonic acid generation in C5a-stimulated human basophils. | 1993 | J. Immunol. | pmid:8245471 |
| Böhme M et al. | Differential inhibition by cyclosporins of primary-active ATP-dependent transporters in the hepatocyte canalicular membrane. | 1993 | FEBS Lett. | pmid:8224162 |
| Ebersole JL et al. | Inflammatory mediators and immunoglobulins in GCF from healthy, gingivitis and periodontitis sites. | 1993 | J. Periodont. Res. | pmid:8263728 |
| Müller D et al. | Stimulation of bile flow and inhibition of biliary secretion of taurocholate and leukotriene C4 in thioacetamide-induced liver fibrosis. | 1993 | Z Gastroenterol | pmid:7483705 |
| Casolaro V et al. | Nimesulide, a sulfonanilide nonsteroidal anti-inflammatory drug, inhibits mediator release from human basophils and mast cells. | 1993 | J. Pharmacol. Exp. Ther. | pmid:7505332 |
| Weide I et al. | Intravascular cysteinyl-leukotriene formation by clotting whole human blood. Evidence from clamped umbilical vein segments and thrombus specimens. | 1993 | Thromb. Res. | pmid:8122190 |
| Westcott JY et al. | Inactivation of peptidoleukotrienes in the isolated perfused rat lung. | 1993 | Arch. Biochem. Biophys. | pmid:7692821 |
| Westcott JY et al. | Inactivation of leukotriene C4 in the airways and subsequent urinary leukotriene E4 excretion in normal and asthmatic subjects. | 1993 | Am. Rev. Respir. Dis. | pmid:7694531 |