Venkatachalam TK et al. |
Substituted heterocyclic thiourea compounds as a new class of anti-allergic agents inhibiting IgE/Fc epsilon RI receptor mediated mast cell leukotriene release. |
2003 |
Bioorg. Med. Chem. |
pmid:12614897
|
Plath KE et al. |
Calcineurin antagonists differentially affect mediator secretion, p38 mitogen-activated protein kinase and extracellular signal-regulated kinases from immunologically activated human basophils. |
2003 |
Clin. Exp. Allergy |
pmid:12614449
|
Kwak WJ et al. |
Papyriflavonol A from Broussonetia papyrifera inhibits the passive cutaneous anaphylaxis reaction and has a secretory phospholipase A2-inhibitory activity. |
2003 |
Biol. Pharm. Bull. |
pmid:12612436
|
Mizutani N |
[Studies on the experimental allergic rhinitis induced by Japanese cedar pollen--role of cysteinyl leukotrienes in nasal allergic symptoms]. |
2003 |
Yakugaku Zasshi |
pmid:12607939
|
Wang DY et al. |
The upper and lower airway responses to nasal challenge with house-dust mite Blomia tropicalis. |
2003 |
Allergy |
pmid:12580812
|
Serio KJ et al. |
Lipopolysaccharide down-regulates the leukotriene C4 synthase gene in the monocyte-like cell line, THP-1. |
2003 |
J. Immunol. |
pmid:12574384
|
Venkatachalam TK et al. |
Inhibition of mast cell leukotriene release by thiourea derivatives. |
2003 |
Bioorg. Med. Chem. Lett. |
pmid:12565956
|
Bellou A et al. |
Constitutive nitric oxide synthase inhibition combined with histamine and serotonin receptor blockade improves the initial ovalbumin-induced arterial hypotension but decreases the survival time in brown norway rats anaphylactic shock. |
2003 |
Shock |
pmid:12558148
|
Mastalerz L et al. |
Clinical and genetic features underlying the response of patients with bronchial asthma to treatment with a leukotriene receptor antagonist. |
2002 |
Eur. J. Clin. Invest. |
pmid:12534456
|
Liu P et al. |
Cysteinyl leukotriene-dependent [Ca2+]i responses to angiotensin II in cardiomyocytes. |
2003 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:12531730
|
Tedla N et al. |
Activation of human eosinophils through leukocyte immunoglobulin-like receptor 7. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12529506
|
Chen ZS et al. |
Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10). |
2003 |
Mol. Pharmacol. |
pmid:12527806
|
Ma L et al. |
Identification and characterization of the canine multidrug resistance-associated protein. |
2002 |
Mol. Cancer Ther. |
pmid:12516967
|
Nagase T et al. |
A potent inhibitor of cytosolic phospholipase A2, arachidonyl trifluoromethyl ketone, attenuates LPS-induced lung injury in mice. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12505870
|
Yang SH et al. |
The stimulatory effects of nasal discharge from patients with perennial allergic rhinitis on normal human neutrophils are normalized after treatment with a new mixed formula of Chinese herbs. |
2002 |
Int. Immunopharmacol. |
pmid:12469937
|
Walch L et al. |
Pharmacological evidence for a novel cysteinyl-leukotriene receptor subtype in human pulmonary artery smooth muscle. |
2002 |
Br. J. Pharmacol. |
pmid:12466244
|
Wiklund CU et al. |
Interactions of volatile anesthetics with cholinergic, tachykinin, and leukotriene mechanisms in isolated Guinea pig bronchial smooth muscle. |
2002 |
Anesth. Analg. |
pmid:12456432
|
Oliveira SH et al. |
Stem cell factor induces eosinophil activation and degranulation: mediator release and gene array analysis. |
2002 |
Blood |
pmid:12453875
|
Ren XQ et al. |
A positively charged amino acid proximal to the C-terminus of TM17 of MRP1 is indispensable for GSH-dependent binding of substrates and for transport of LTC4. |
2002 |
Biochemistry |
pmid:12450376
|
Evans JF |
Cysteinyl leukotriene receptors. |
2002 |
Prostaglandins Other Lipid Mediat. |
pmid:12432945
|
Uemura M et al. |
Cysteinyl leukotrienes in the bile of patients with obstructive jaundice. |
2002 |
J. Gastroenterol. |
pmid:12424566
|
Belinsky MG et al. |
Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6). |
2002 |
Cancer Res. |
pmid:12414644
|
Tabas LB and Dantzig AH |
A high-throughput assay for measurement of multidrug resistance protein-mediated transport of leukotriene C4 into membrane vesicles. |
2002 |
Anal. Biochem. |
pmid:12413474
|
Lee SH and Altenberg GA |
Transport of leukotriene C4 by a cysteine-less multidrug resistance protein 1 (MRP1). |
2003 |
Biochem. J. |
pmid:12398766
|
Hashimoto K et al. |
Trafficking and functional defects by mutations of the ATP-binding domains in MRP2 in patients with Dubin-Johnson syndrome. |
2002 |
Hepatology |
pmid:12395335
|
Koike K et al. |
Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1. |
2002 |
J. Biol. Chem. |
pmid:12388549
|
Vargaftig BB and Singer M |
Leukotrienes, IL-13, and chemokines cooperate to induce BHR and mucus in allergic mouse lungs. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12388339
|
Keitel V et al. |
A common Dubin-Johnson syndrome mutation impairs protein maturation and transport activity of MRP2 (ABCC2). |
2003 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:12388192
|
Oleschuk CJ et al. |
Substitution of Trp1242 of TM17 alters substrate specificity of human multidrug resistance protein 3. |
2003 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:12388190
|
Liu S et al. |
Neuroimmune interactions in guinea pig stomach and small intestine. |
2003 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:12388180
|
Tsuruoka S et al. |
Functional analysis of ABCA8, a new drug transporter. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12379217
|
ten Hove T et al. |
Differential susceptibility of multidrug resistance protein-1 deficient mice to DSS and TNBS-induced colitis. |
2002 |
Dig. Dis. Sci. |
pmid:12353855
|
Nobata K et al. |
Alpha(1L)-, but not alpha(1H)-, adrenoceptor antagonist prevents allergic bronchoconstriction in guinea pigs in vivo. |
2002 |
Eur. J. Pharmacol. |
pmid:12323390
|
Suzuki Y et al. |
Silver activates calcium signals in rat basophilic leukemia-2H3 mast cells by a mechanism that differs from the Fc epsilon RI-activated response. |
2002 |
J. Immunol. |
pmid:12244196
|
Bandeira-Melo C et al. |
Intracrine cysteinyl leukotriene receptor-mediated signaling of eosinophil vesicular transport-mediated interleukin-4 secretion. |
2002 |
J. Exp. Med. |
pmid:12235216
|
Yang Y et al. |
Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1. |
2002 |
J. Biol. Chem. |
pmid:12235150
|
Hagmann W et al. |
Reconstitution of transport-active multidrug resistance protein 2 (MRP2; ABCC2) in proteoliposomes. |
2002 |
Biol. Chem. |
pmid:12222674
|
Gebhardt T et al. |
Cultured human intestinal mast cells express functional IL-3 receptors and respond to IL-3 by enhancing growth and IgE receptor-dependent mediator release. |
2002 |
Eur. J. Immunol. |
pmid:12209644
|
Haimeur A et al. |
Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity. |
2002 |
J. Biol. Chem. |
pmid:12186871
|
Arango P and Kountakis SE |
Presence of cysteinyl leukotrienes in asthmatic patients with chronic sinusitis. |
2002 |
Laryngoscope |
pmid:12169896
|
Ohashi M et al. |
Effects of phalloidin on the biliary excretion of cholephilic compounds in rats. |
2002 |
Pharmacology |
pmid:12169763
|
Hashizume K and Black KL |
Increased endothelial vesicular transport correlates with increased blood-tumor barrier permeability induced by bradykinin and leukotriene C4. |
2002 |
J. Neuropathol. Exp. Neurol. |
pmid:12152787
|
Gibbs BF et al. |
Regulation of mediator secretion in human basophils by p38 mitogen-activated protein kinase: phosphorylation is sensitive to the effects of phosphatidylinositol 3-kinase inhibitors and calcium mobilization. |
2002 |
J. Leukoc. Biol. |
pmid:12149431
|
Thomas LL et al. |
Immobilized lactoferrin is a stimulus for eosinophil activation. |
2002 |
J. Immunol. |
pmid:12097406
|
Bandeira-Melo C et al. |
Cysteinyl leukotrienes induce IL-4 release from cord blood-derived human eosinophils. |
2002 |
J. Allergy Clin. Immunol. |
pmid:12063527
|
Fernández SB et al. |
Role of the N-terminal transmembrane region of the multidrug resistance protein MRP2 in routing to the apical membrane in MDCKII cells. |
2002 |
J. Biol. Chem. |
pmid:12060660
|
Oliveira SH et al. |
Increased responsiveness of murine eosinophils to MIP-1beta (CCL4) and TCA-3 (CCL1) is mediated by their specific receptors, CCR5 and CCR8. |
2002 |
J. Leukoc. Biol. |
pmid:12050188
|
Conrad S et al. |
A naturally occurring mutation in MRP1 results in a selective decrease in organic anion transport and in increased doxorubicin resistance. |
2002 |
Pharmacogenetics |
pmid:12042670
|
Mao Q et al. |
GSH-dependent photolabeling of multidrug resistance protein MRP1 (ABCC1) by [125I]LY475776. Evidence of a major binding site in the COOH-proximal membrane spanning domain. |
2002 |
J. Biol. Chem. |
pmid:12034727
|
Christmas P et al. |
Membrane localization and topology of leukotriene C4 synthase. |
2002 |
J. Biol. Chem. |
pmid:12023288
|
de las Heras B et al. |
Effects of six diterpenes on macrophage eicosanoid biosynthesis. |
2001 |
Life Sci. |
pmid:12005260
|
Sawatzky DA et al. |
Eosinophil adhesion to cholinergic nerves via ICAM-1 and VCAM-1 and associated eosinophil degranulation. |
2002 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12003784
|
Kingham PJ et al. |
Adhesion-dependent interactions between eosinophils and cholinergic nerves. |
2002 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12003778
|
Ravasi S et al. |
Pharmacological differences among CysLT(1) receptor antagonists with respect to LTC(4) and LTD(4) in human lung parenchyma. |
2002 |
Biochem. Pharmacol. |
pmid:11996896
|
Kolaczkowska E et al. |
Early vascular permeability in murine experimental peritonitis is co-mediated by resident peritoneal macrophages and mast cells: crucial involvement of macrophage-derived cysteinyl-leukotrienes. |
2002 |
Inflammation |
pmid:11989789
|
Bandeira-Melo C et al. |
IL-16 promotes leukotriene C(4) and IL-4 release from human eosinophils via CD4- and autocrine CCR3-chemokine-mediated signaling. |
2002 |
J. Immunol. |
pmid:11971026
|
Norman BH et al. |
Tricyclic isoxazoles are novel inhibitors of the multidrug resistance protein (MRP1). |
2002 |
Bioorg. Med. Chem. Lett. |
pmid:11958985
|
Ahamed J and Ali H |
Distinct roles of receptor phosphorylation, G protein usage, and mitogen-activated protein kinase activation on platelet activating factor-induced leukotriene C(4) generation and chemokine production. |
2002 |
J. Biol. Chem. |
pmid:11934880
|
Maekawa A et al. |
Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses. |
2002 |
J. Biol. Chem. |
pmid:11932261
|
Zhang DW et al. |
Determinants of the substrate specificity of multidrug resistance protein 1: role of amino acid residues with hydrogen bonding potential in predicted transmembrane helix 17. |
2002 |
J. Biol. Chem. |
pmid:11925441
|
Neu IS et al. |
Leukotrienes in patients with clinically active multiple sclerosis. |
2002 |
Acta Neurol. Scand. |
pmid:11903112
|
Guo A et al. |
Delineating the contribution of secretory transporters in the efflux of etoposide using Madin-Darby canine kidney (MDCK) cells overexpressing P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1), and canalicular multispecific organic anion transporter (cMOAT). |
2002 |
Drug Metab. Dispos. |
pmid:11901101
|
Jedlitschky G and Keppler D |
Transport of leukotriene C4 and structurally related conjugates. |
2002 |
Vitam. Horm. |
pmid:11898391
|
Iliás A et al. |
Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6). |
2002 |
J. Biol. Chem. |
pmid:11880368
|
Küsters S et al. |
Effects of antihistamines on leukotriene and cytokine release from dispersed nasal polyp cells. |
2002 |
Arzneimittelforschung |
pmid:11878205
|
Bäck M et al. |
Modulation of vascular tone and reactivity by nitric oxide in porcine pulmonary arteries and veins. |
2002 |
Acta Physiol. Scand. |
pmid:11851592
|
Sakata K and Bäck M |
Receptor preferences of cysteinyl-leukotrienes in the guinea pig lung parenchyma. |
2002 |
Eur. J. Pharmacol. |
pmid:11834255
|
Shon YH et al. |
Effect of Astragali radix extract on lipopolysaccharide-induced inflammation in human amnion. |
2002 |
Biol. Pharm. Bull. |
pmid:11824562
|
Bermejo BP et al. |
Sesquiterpenes from Jasonia glutinosa: in vitro anti-inflammatory activity. |
2002 |
Biol. Pharm. Bull. |
pmid:11824534
|
Fukuishi N et al. |
Antiallergic effect of ardisiaquinone A, a potent 5-lipoxygenase inhibitor. |
2001 |
Phytomedicine |
pmid:11824521
|
Chrubasik S et al. |
Harpagophytum extracts. |
2002 |
Clin. Pharmacol. Ther. |
pmid:11823764
|
Suzuki R and Freed AN |
Heparin inhibits hyperventilation-induced late-phase hyperreactivity in dogs. |
2002 |
Am. J. Respir. Crit. Care Med. |
pmid:11779726
|
Wang J et al. |
[The effects of resuscitation with hypertonic saline solution on the postburn pulmonary injury in scalded dogs]. |
2001 |
Zhonghua Shao Shang Za Zhi |
pmid:11774813
|
Malaviya R and Uckun FM |
Role of STAT6 in IgE receptor/FcepsilonRI-mediated late phase allergic responses of mast cells. |
2002 |
J. Immunol. |
pmid:11751988
|
Miller DS et al. |
Xenobiotic efflux pumps in isolated fish brain capillaries. |
2002 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:11742838
|
Miura K et al. |
Localizing a control region in the pathway to leukotriene C(4) secretion following stimulation of human basophils with anti-IgE antibody. |
2001 |
J. Immunol. |
pmid:11739523
|
Fernández MA et al. |
New insights into the mechanism of action of the anti-inflammatory triterpene lupeol. |
2001 |
J. Pharm. Pharmacol. |
pmid:11732756
|
Martin V et al. |
Molecular cloning and functional characterization of murine cysteinyl-leukotriene 1 (CysLT(1)) receptors. |
2001 |
Biochem. Pharmacol. |
pmid:11705452
|
Bölke E et al. |
Inflammatory response during abdominal and thyroid surgery: a prospective clinical trial on mediator release. |
2001 |
Shock |
pmid:11699069
|
Miura K et al. |
Piceatannol is an effective inhibitor of IgE-mediated secretion from human basophils but is neither selective for this receptor nor acts on syk kinase at concentrations where mediator release inhibition occurs. |
2001 |
Clin. Exp. Allergy |
pmid:11696049
|
Terlouw SA et al. |
Role of multidrug resistance protein 2 (MRP2) in glutathione-bimane efflux from Caco-2 and rat renal proximal tubule cells. |
2001 |
Br. J. Pharmacol. |
pmid:11682439
|
Ohno N et al. |
Prognostic significance of multidrug resistance protein in adult T-cell leukemia. |
2001 |
Clin. Cancer Res. |
pmid:11595704
|
Duffy SM et al. |
Resting and activation-dependent ion channels in human mast cells. |
2001 |
J. Immunol. |
pmid:11591748
|
Hui Y et al. |
The murine cysteinyl leukotriene 2 (CysLT2) receptor. cDNA and genomic cloning, alternative splicing, and in vitro characterization. |
2001 |
J. Biol. Chem. |
pmid:11591709
|
Schroeder JT et al. |
Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine. |
2001 |
Clin. Exp. Allergy |
pmid:11591186
|
Kamohara M et al. |
Functional characterization of cysteinyl leukotriene CysLT(2) receptor on human coronary artery smooth muscle cells. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11587533
|
Thomas LL et al. |
Peptide-based analysis of amino acid sequences important to the biological activity of eosinophil granule major basic protein. |
2001 |
Immunol. Lett. |
pmid:11578692
|
Sano A et al. |
Regulation of eosinophil function by phosphatidylinositol-specific PLC and cytosolic PLA(2). |
2001 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:11557588
|
Malaviya R and Uckun FM |
Leflunomide metabolite analogue alpha-cyano-beta-hydroxy-beta-methyl-N-[3-(trifluoromethyl)phenyl]propenamide inhibits IgE/FcepsilonRI receptor-mediated mast cell leukotriene release and allergic asthma in mice. |
2001 Sep-Oct |
Am J Ther |
pmid:11550070
|
Tornhamre S et al. |
Inhibitory effects of helenalin and related compounds on 5-lipoxygenase and leukotriene C(4) synthase in human blood cells. |
2001 |
Biochem. Pharmacol. |
pmid:11543725
|
Wehner J and Neuber K |
Staphylococcus aureus enterotoxins induce histamine and leukotriene release in patients with atopic eczema. |
2001 |
Br. J. Dermatol. |
pmid:11531797
|
Abad MJ et al. |
Effects of furocoumarins from Cachrys trifida on some macrophage functions. |
2001 |
J. Pharm. Pharmacol. |
pmid:11518028
|
Bölke E et al. |
Changes of gut barrier function during anesthesia and cardiac surgery. |
2001 |
Angiology |
pmid:11515987
|
Qian YM et al. |
Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: evidence of differential interactions with NH2- and COOH-proximal halves of the protein. |
2001 |
J. Biol. Chem. |
pmid:11507101
|
Aoki M et al. |
Studies on mechanisms of low emetogenicity of YM976, a novel phosphodiesterase type 4 inhibitor. |
2001 |
J. Pharmacol. Exp. Ther. |
pmid:11504812
|
Ito K et al. |
Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity. |
2001 |
J. Biol. Chem. |
pmid:11500505
|
Miura K et al. |
Differences in functional consequences and signal transduction induced by IL-3, IL-5, and nerve growth factor in human basophils. |
2001 |
J. Immunol. |
pmid:11490016
|
Bäck M et al. |
An alternative pathway for metabolism of leukotriene D(4): effects on contractions to cysteinyl-leukotrienes in the guinea-pig trachea. |
2001 |
Br. J. Pharmacol. |
pmid:11487525
|
Strenzke N et al. |
Mercuric chloride enhances immunoglobulin E-dependent mediator release from human basophils. |
2001 |
Toxicol. Appl. Pharmacol. |
pmid:11485386
|
Falcón-Pérez JM et al. |
Domain interactions in the yeast ATP binding cassette transporter Ycf1p: intragenic suppressor analysis of mutations in the nucleotide binding domains. |
2001 |
J. Bacteriol. |
pmid:11466279
|