|
|
|
|
pmid:24925646
|
Ezeamuzie CI et al. |
Antiallergic and antiasthmatic effects of a novel enhydrazinone ester (CEE-1): inhibition of activation of both mast cells and eosinophils. |
2014 |
J. Pharmacol. Exp. Ther. |
pmid:24917545
|
|
|
|
|
pmid:24892983
|
Bertin J et al. |
Exposure of human astrocytes to leukotriene C4 promotes a CX3CL1/fractalkine-mediated transmigration of HIV-1-infected CD4⺠T cells across an in vitro blood-brain barrier model. |
2014 |
Virology |
pmid:24725939
|
|
|
|
|
pmid:24710901
|
Lee JF et al. |
Lipoxygenase pathway mediates increases of airway resistance and lung inflation induced by exposure to nanotitanium dioxide in rats. |
2014 |
Oxid Med Cell Longev |
pmid:24693335
|
Pinho BR et al. |
Modulation of basophils' degranulation and allergy-related enzymes by monomeric and dimeric naphthoquinones. |
2014 |
PLoS ONE |
pmid:24587235
|
Zhang X et al. |
Complex role of STIM1 in the activation of store-independent Orai1/3 channels. |
2014 |
J. Gen. Physiol. |
pmid:24567509
|
Xu R et al. |
Novel polyhydroxylated steroids from the East China Sea gorgonian Echinogorgia sassapo reticulata with suppressive activity of leukotriene C4 generation and degranulation in bone marrow-derived mast cells. |
2014 |
J Asian Nat Prod Res |
pmid:24437431
|
Niegowski D et al. |
Crystal structures of leukotriene C4 synthase in complex with product analogs: implications for the enzyme mechanism. |
2014 |
J. Biol. Chem. |
pmid:24366866
|
Kawakami Y et al. |
Neutralization of leukotriene C4 and D4 activity by monoclonal and single-chain antibodies. |
2014 |
Biochim. Biophys. Acta |
pmid:24361619
|
Magi S et al. |
5-Lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor-induced cell migration through Tiam1 upregulation and Rac1 activation. |
2014 |
Cancer Sci. |
pmid:24350867
|
Gao YB et al. |
Low temperature inhibits pollen tube growth by disruption of both tip-localized reactive oxygen species and endocytosis in Pyrus bretschneideri Rehd. |
2014 |
Plant Physiol. Biochem. |
pmid:24321875
|
Cummings HE et al. |
Cutting edge: Leukotriene C4 activates mouse platelets in plasma exclusively through the type 2 cysteinyl leukotriene receptor. |
2013 |
J. Immunol. |
pmid:24244016
|
Talbot SF et al. |
Accumulation of leukotriene C4 and histamine in human allergic skin reactions. |
1985 |
J. Clin. Invest. |
pmid:2411760
|
Cole SP |
Targeting multidrug resistance protein 1 (MRP1, ABCC1): past, present, and future. |
2014 |
Annu. Rev. Pharmacol. Toxicol. |
pmid:24050699
|
Long EK et al. |
Fatty acids induce leukotriene C4 synthesis in macrophages in a fatty acid binding protein-dependent manner. |
2013 |
Biochim. Biophys. Acta |
pmid:24046860
|
Xiang Y et al. |
Anti-inflammatory effect of acetylpuerarin on eicosanoid signaling pathway in primary rat astrocytes. |
2014 |
J. Mol. Neurosci. |
pmid:24026619
|
Seki K et al. |
Oxidative stress potentially enhances FcεRI-mediated leukotriene C4 release dependent on the late-phase increase of intracellular glutathione in mast cells. |
2013 |
Biochem. Biophys. Res. Commun. |
pmid:23998930
|
Quan GH et al. |
Anti-allergic flavones from Arthraxon hispidus. |
2013 |
Chem. Pharm. Bull. |
pmid:23995356
|
Suram S et al. |
Cytosolic phospholipase A(2)α and eicosanoids regulate expression of genes in macrophages involved in host defense and inflammation. |
2013 |
PLoS ONE |
pmid:23950842
|
James A et al. |
The influence of aspirin on release of eoxin C4, leukotriene C4 and 15-HETE, in eosinophilic granulocytes isolated from patients with asthma. |
2013 |
Int. Arch. Allergy Immunol. |
pmid:23921438
|
Zhang X et al. |
Mechanisms of STIM1 activation of store-independent leukotriene C4-regulated Ca2+ channels. |
2013 |
Mol. Cell. Biol. |
pmid:23878392
|
Ikeno Y et al. |
Wasp venom allergy: effect of anti-IgE antibody on wasp venom anaphylaxis in a mouse model. |
2013 |
Asian Pac. J. Allergy Immunol. |
pmid:23859410
|
Macglashan DW and Saini SS |
Omalizumab increases the intrinsic sensitivity of human basophils to IgE-mediated stimulation. |
2013 |
J. Allergy Clin. Immunol. |
pmid:23791510
|
Milara J et al. |
Bafetinib inhibits functional responses of human eosinophils in vitro. |
2013 |
Eur. J. Pharmacol. |
pmid:23747655
|
Koketsu R et al. |
Pretreatment with low levels of FcεRI-crosslinking stimulation enhances basophil mediator release. |
2013 |
Int. Arch. Allergy Immunol. |
pmid:23711850
|
Syslová K et al. |
Immunomagnetic molecular probe with UHPLC-MS/MS: a promising way for reliable bronchial asthma diagnostics based on quantification of cysteinyl leukotrienes. |
2013 Jul-Aug |
J Pharm Biomed Anal |
pmid:23644905
|
Jung HW et al. |
Comparison of the efficacy of KOB03, ketotifen, and montelukast in an experimental mouse model of allergic rhinitis. |
2013 |
Int. Immunopharmacol. |
pmid:23643816
|
Gurzeler U et al. |
In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8. |
2013 |
Allergy |
pmid:23590216
|
Welsh DG |
The many faces of Orai. |
2013 |
Circ. Res. |
pmid:23538273
|
Kanaoka Y et al. |
Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligand. |
2013 |
J. Biol. Chem. |
pmid:23504326
|
Keum JH et al. |
The anti-inflammatory effect of Cheongseoikki-tang ethanol extract on allergic reactions mediated by bone marrow-derived mast cells. |
2013 |
Chin J Integr Med |
pmid:23494327
|
Hirata H et al. |
Leukotriene C4 aggravates bleomycin-induced pulmonary fibrosis in mice. |
2013 |
Respirology |
pmid:23432979
|
Ahmad S et al. |
Catalytic characterization of human microsomal glutathione S-transferase 2: identification of rate-limiting steps. |
2013 |
Biochemistry |
pmid:23409838
|
Yoo JM et al. |
Inhibitory effect of N-Acyl dopamines on IgE-mediated allergic response in RBL-2H3 cells. |
2013 |
Lipids |
pmid:23377981
|
Zhou M et al. |
In vivo intranasal anti-CD23 treatment inhibits allergic responses in a murine model of allergic rhinitis. |
2013 |
J. Mol. Histol. |
pmid:23377922
|
González-Cobos JC et al. |
Store-independent Orai1/3 channels activated by intracrine leukotriene C4: role in neointimal hyperplasia. |
2013 |
Circ. Res. |
pmid:23349245
|
Takase B |
[Responses of plasma eicosanoids and hemodynamics to myocardial ischemia and the salutary effect of calcium entry blocker]. |
1990 |
Nippon Ika Daigaku Zasshi |
pmid:2329180
|
Meszaros P et al. |
Long term myriocin treatment increases MRP1 transport activity. |
2013 |
Int. J. Biochem. Cell Biol. |
pmid:23178537
|
Lester GD and Rice BL |
Effects of leukotriene C4 on the bioelectric properties and ion transport of equine tracheal epithelium. |
2012 |
Am. J. Vet. Res. |
pmid:23176432
|
Dong X et al. |
Urotensin II promotes the production of LTC4 in rat aortic adventitial fibroblasts through NF-κB-5-LO pathway by p38 MAPK and ERK activations. |
2013 |
Heart Vessels |
pmid:23053343
|
Lu Y et al. |
Saucerneol D inhibits eicosanoid generation and degranulation through suppression of Syk kinase in mast cells. |
2012 |
Food Chem. Toxicol. |
pmid:22982805
|
Liu W et al. |
Coupling of UDP-glucuronosyltransferases and multidrug resistance-associated proteins is responsible for the intestinal disposition and poor bioavailability of emodin. |
2012 |
Toxicol. Appl. Pharmacol. |
pmid:22982073
|
Fugazzola M et al. |
Non-genomic action of beclomethasone dipropionate on bronchoconstriction caused by leukotriene C4 in precision cut lung slices in the horse. |
2012 |
BMC Vet. Res. |
pmid:22963524
|
Song HH et al. |
Anti-inflammatory and anti-allergic effect of Agaricus blazei extract in bone marrow-derived mast cells. |
2012 |
Am. J. Chin. Med. |
pmid:22928836
|
Hong F and Yang S |
Ischemic preconditioning decreased leukotriene C4 formation by depressing leukotriene C4 synthase expression and activity during hepatic I/R injury in rats. |
2012 |
J. Surg. Res. |
pmid:22921920
|
Jin Y et al. |
Pinusolide isolated from Biota orientalis inhibits 5-lipoxygenase dependent leukotriene C4 generation by blocking c-Jun N-terminal kinase pathway in mast cells. |
2012 |
Biol. Pharm. Bull. |
pmid:22863941
|
Ilarraza R et al. |
Montelukast inhibits leukotriene stimulation of human dendritic cells in vitro. |
2012 |
Int. Arch. Allergy Immunol. |
pmid:22846852
|
Pelclová D et al. |
Leukotrienes B4, C4, D4 and E4 in the exhaled breath condensate (EBC), blood and urine in patients with pneumoconiosis. |
2012 |
Ind Health |
pmid:22785421
|
Dellon ES et al. |
Diagnostic utility of major basic protein, eotaxin-3, and leukotriene enzyme staining in eosinophilic esophagitis. |
2012 |
Am. J. Gastroenterol. |
pmid:22777338
|
Hanjalic-Beck A et al. |
Chlormadinone acetate suppresses prostaglandin biosynthesis in human endometrial explants. |
2012 |
Fertil. Steril. |
pmid:22769735
|
Han YS et al. |
Macelignan inhibits histamine release and inflammatory mediator production in activated rat basophilic leukemia mast cells. |
2012 |
Inflammation |
pmid:22729280
|
Stolarczyk EI et al. |
Casein kinase 2α regulates multidrug resistance-associated protein 1 function via phosphorylation of Thr249. |
2012 |
Mol. Pharmacol. |
pmid:22695718
|
Wu L et al. |
Lipoxin A4 inhibits 5-lipoxygenase translocation and leukotrienes biosynthesis to exert a neuroprotective effect in cerebral ischemia/reperfusion injury. |
2012 |
J. Mol. Neurosci. |
pmid:22661361
|
Piotrowska-Tomala KK et al. |
Lipopolysaccharides, cytokines, and nitric oxide affect secretion of prostaglandins and leukotrienes by bovine mammary gland epithelial cells. |
2012 |
Domest. Anim. Endocrinol. |
pmid:22608768
|
Baker SR et al. |
The pharmacology of N-methyl LTC4; a metabolically stable LTC4-mimetic. |
1990 |
Prostaglandins |
pmid:2255765
|
Eaton A et al. |
Cysteinyl leukotriene signaling through perinuclear CysLT(1) receptors on vascular smooth muscle cells transduces nuclear calcium signaling and alterations of gene expression. |
2012 |
J. Mol. Med. |
pmid:22527886
|
Lechowski S et al. |
Combined arginine and glutamine decrease release of de novo synthesized leukotrienes and expression of proinflammatory cytokines in activated human intestinal mast cells. |
2013 |
Eur J Nutr |
pmid:22527286
|
Qin L et al. |
Effect of multiple cysteine substitutions on the functionality of human multidrug resistance protein 1 expressed in human embryonic kidney 293 cells: identification of residues essential for function. |
2012 |
Drug Metab. Dispos. |
pmid:22511347
|
Kar P et al. |
Different agonists recruit different stromal interaction molecule proteins to support cytoplasmic Ca2+ oscillations and gene expression. |
2012 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22509043
|
Nagy E et al. |
Increased transcript level of poly(ADP-ribose) polymerase (PARP-1) in human tricuspid compared with bicuspid aortic valves correlates with the stenosis severity. |
2012 |
Biochem. Biophys. Res. Commun. |
pmid:22450322
|
Secatto A et al. |
5-Lipoxygenase deficiency impairs innate and adaptive immune responses during fungal infection. |
2012 |
PLoS ONE |
pmid:22448213
|
Nunomura S et al. |
The FcRβ- and γ-ITAMs play crucial but distinct roles in the full activation of mast cells induced by IgEκ and Protein L. |
2012 |
J. Immunol. |
pmid:22430736
|
Oyoshi MK et al. |
Eosinophil-derived leukotriene C4 signals via type 2 cysteinyl leukotriene receptor to promote skin fibrosis in a mouse model of atopic dermatitis. |
2012 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22416124
|
Kidron H et al. |
Impact of probe compound in MRP2 vesicular transport assays. |
2012 |
Eur J Pharm Sci |
pmid:22406294
|
Lu Y et al. |
Citreorosein inhibits degranulation and leukotriene Câ‚„ generation through suppression of Syk pathway in mast cells. |
2012 |
Mol. Cell. Biochem. |
pmid:22395859
|
Eun JC et al. |
The 5-lipoxygenase pathway is required for acute lung injury following hemorrhagic shock. |
2012 |
Shock |
pmid:22392149
|
Zhang Y et al. |
[Effects of polydatin on bleomycin-induced pulmonary fibrosis in rats]. |
2011 |
Zhongguo Zhong Yao Za Zhi |
pmid:22368872
|
Dannull J et al. |
Leukotriene C4 induces migration of human monocyte-derived dendritic cells without loss of immunostimulatory function. |
2012 |
Blood |
pmid:22323449
|
Muccitelli RM et al. |
Cysteinyl leukotriene receptor assays. |
2001 |
Curr Protoc Pharmacol |
pmid:22293965
|
Li X et al. |
Natural vanadium-containing Jeju groundwater inhibits immunoglobulin E-mediated anaphylactic reaction and suppresses eicosanoid generation and degranulation in bone marrow derived-mast cells. |
2012 |
Biol. Pharm. Bull. |
pmid:22293352
|
Iram SH and Cole SP |
Mutation of Glu521 or Glu535 in cytoplasmic loop 5 causes differential misfolding in multiple domains of multidrug and organic anion transporter MRP1 (ABCC1). |
2012 |
J. Biol. Chem. |
pmid:22232552
|
Ng SW et al. |
Cysteinyl leukotriene type I receptor desensitization sustains Ca2+-dependent gene expression. |
2012 |
Nature |
pmid:22230957
|
Chae HS et al. |
Anti-allergic effect of a chloroform-soluble extract of Cinnamomum cambodianum in bone marrow-derived mast cells. |
2012 |
Immunopharmacol Immunotoxicol |
pmid:22229445
|
Rinaldo-Matthis A et al. |
Pre-steady-state kinetic characterization of thiolate anion formation in human leukotriene Câ‚„ synthase. |
2012 |
Biochemistry |
pmid:22217203
|
Maurer M and Church MK |
Inflammatory skin responses induced by icatibant injection are mast cell mediated and attenuated by H(1)-antihistamines. |
2012 |
Exp. Dermatol. |
pmid:22142018
|
Pereira-Vega A et al. |
Premenstrual asthma and leukotriene variations in the menstrual cycle. |
2012 Nov-Dec |
Allergol Immunopathol (Madr) |
pmid:22115570
|
Sodani K et al. |
Multidrug resistance associated proteins in multidrug resistance. |
2012 |
Chin J Cancer |
pmid:22098952
|
Jiang W et al. |
UDP-glucuronosyltransferase (UGT) 1A9-overexpressing HeLa cells is an appropriate tool to delineate the kinetic interplay between breast cancer resistance protein (BRCP) and UGT and to rapidly identify the glucuronide substrates of BCRP. |
2012 |
Drug Metab. Dispos. |
pmid:22071170
|
Kim SJ et al. |
Manassantin A isolated from Saururus chinensis inhibits 5-lipoxygenase-dependent leukotriene C4 generation by blocking mitogen-activated protein kinase activation in mast cells. |
2011 |
Biol. Pharm. Bull. |
pmid:22040894
|
Jin M et al. |
Anti-inflammatory activity of 6-hydroxy-2,7-dimethoxy-1,4-henanthraquinone from tuberous roots of yam (Dioscorea batatas) through inhibition of prostaglandin Dâ‚‚ and leukotriene Câ‚„ production in mouse bone marrow-derived mast cells. |
2011 |
Arch. Pharm. Res. |
pmid:21975811
|
Shaari K et al. |
Bioassay-guided identification of an anti-inflammatory prenylated acylphloroglucinol from Melicope ptelefolia and molecular insights into its interaction with 5-lipoxygenase. |
2011 |
Bioorg. Med. Chem. |
pmid:21958738
|
Lu Y et al. |
Emodin, a naturally occurring anthraquinone derivative, suppresses IgE-mediated anaphylactic reaction and mast cell activation. |
2011 |
Biochem. Pharmacol. |
pmid:21907188
|
Alvarez C et al. |
Leukotriene C(4) prevents the complete maturation of murine dendritic cells and modifies interleukin-12/interleukin-23 balance. |
2011 |
Immunology |
pmid:21896013
|
Furukawa M et al. |
Terpenoids and phenethyl glucosides from Hyssopus cuspidatus (Labiatae). |
2011 |
Phytochemistry |
pmid:21893325
|
Chae HS and Chin YW |
Anti-allergic effect of lambertianic acid from Thuja orientalis in mouse bone marrow-derived mast cells. |
2012 |
Immunopharmacol Immunotoxicol |
pmid:21854102
|
Szabó Z et al. |
ABCC6 does not transport adenosine - relevance to pathomechanism of pseudoxanthoma elasticum. |
2011 |
Mol. Genet. Metab. |
pmid:21813308
|
Wang JL et al. |
[The mechanism of airway inflammation in eosinophilic bronchitis and cough variant asthma]. |
2011 |
Zhonghua Jie He He Hu Xi Za Zhi |
pmid:21781515
|
Carnini C et al. |
Synthesis of cysteinyl leukotrienes in human endothelial cells: subcellular localization and autocrine signaling through the CysLT2 receptor. |
2011 |
FASEB J. |
pmid:21753081
|
Jin M et al. |
Luteolin-7-O-glucoside suppresses leukotriene C(4) production and degranulation by inhibiting the phosphorylation of mitogen activated protein kinases and phospholipase Cγ1 in activated mouse bone marrow-derived mast cells. |
2011 |
Biol. Pharm. Bull. |
pmid:21720009
|
Megaraj V et al. |
Functional analysis of nonsynonymous single nucleotide polymorphisms of multidrug resistance-associated protein 2 (ABCC2). |
2011 |
Pharmacogenet. Genomics |
pmid:21691255
|
Al-Amran FG et al. |
Leukotriene biosynthesis inhibition ameliorates acute lung injury following hemorrhagic shock in rats. |
2011 |
J Cardiothorac Surg |
pmid:21649921
|
Saino H et al. |
The catalytic architecture of leukotriene C4 synthase with two arginine residues. |
2011 |
J. Biol. Chem. |
pmid:21454538
|
Wickham S et al. |
Gamma-glutamyl compounds: substrate specificity of gamma-glutamyl transpeptidase enzymes. |
2011 |
Anal. Biochem. |
pmid:21447318
|
Hirata H et al. |
Over-expression of the LTC4 synthase gene in mice reproduces human aspirin-induced asthma. |
2011 |
Clin. Exp. Allergy |
pmid:21429049
|
Mackay GA and Stewart AG |
R2D(2) for C(4)Eo: an 'alliance' of PGD(2) receptors is required for LTC(4) production by human eosinophils. |
2011 |
Br. J. Pharmacol. |
pmid:21426314
|
Nagy E et al. |
Upregulation of the 5-lipoxygenase pathway in human aortic valves correlates with severity of stenosis and leads to leukotriene-induced effects on valvular myofibroblasts. |
2011 |
Circulation |
pmid:21403093
|
Huang SC |
Leukotriene-induced contraction is mediated by cysteinyl leukotriene receptor CysLT1 in guinea pig fundus but by CysLT1 and CysLT2 in antrum. |
2011 |
Life Sci. |
pmid:21396378
|
Dartt DA et al. |
Conjunctival goblet cell secretion stimulated by leukotrienes is reduced by resolvins D1 and E1 to promote resolution of inflammation. |
2011 |
J. Immunol. |
pmid:21357260
|