LTC4

Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.

Cross Reference

Introduction

To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with LTC4?

LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with LTC4

MeSH term MeSH ID Detail
Osteosarcoma D012516 50 associated lipids
Rhinitis, Allergic, Perennial D012221 6 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Pseudoxanthoma Elasticum D011561 2 associated lipids
Pneumococcal Infections D011008 7 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Phlebitis D010689 1 associated lipids
Peritonitis D010538 38 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Per page 10 20 50 100 | Total 75

PubChem Associated disorders and diseases

What pathways are associated with LTC4

Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with LTC4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with LTC4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with LTC4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with LTC4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with LTC4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with LTC4

Download all related citations
Per page 10 20 50 100 | Total 1173
Authors Title Published Journal PubMed Link
Gao YB et al. Low temperature inhibits pollen tube growth by disruption of both tip-localized reactive oxygen species and endocytosis in Pyrus bretschneideri Rehd. 2014 Plant Physiol. Biochem. pmid:24321875
Bukiya AN et al. Activation of calcium- and voltage-gated potassium channels of large conductance by leukotriene B4. 2014 J. Biol. Chem. pmid:25371198
Syslová K et al. Immunomagnetic molecular probe with UHPLC-MS/MS: a promising way for reliable bronchial asthma diagnostics based on quantification of cysteinyl leukotrienes. 2013 Jul-Aug J Pharm Biomed Anal pmid:23644905
Keum JH et al. The anti-inflammatory effect of Cheongseoikki-tang ethanol extract on allergic reactions mediated by bone marrow-derived mast cells. 2013 Chin J Integr Med pmid:23494327
Yoo JM et al. Inhibitory effect of N-Acyl dopamines on IgE-mediated allergic response in RBL-2H3 cells. 2013 Lipids pmid:23377981
Ahmad S et al. Catalytic characterization of human microsomal glutathione S-transferase 2: identification of rate-limiting steps. 2013 Biochemistry pmid:23409838
Hirata H et al. Leukotriene C4 aggravates bleomycin-induced pulmonary fibrosis in mice. 2013 Respirology pmid:23432979
Macglashan DW and Saini SS Omalizumab increases the intrinsic sensitivity of human basophils to IgE-mediated stimulation. 2013 J. Allergy Clin. Immunol. pmid:23791510
Quan GH et al. Anti-allergic flavones from Arthraxon hispidus. 2013 Chem. Pharm. Bull. pmid:23995356
Cummings HE et al. Cutting edge: Leukotriene C4 activates mouse platelets in plasma exclusively through the type 2 cysteinyl leukotriene receptor. 2013 J. Immunol. pmid:24244016