Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.
To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with LTC4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Jordan TR et al. | An approach of immunoneurological aspects in nasal allergic late phase. | 2005 Sep-Oct | Allergy Asthma Proc | pmid:16450573 |
Wang D et al. | An approach to the understanding of the nasal early-phase reaction induced by nasal allergen challenge. | 1997 | Allergy | pmid:9105520 |
Piette V et al. | Sinus CT scans and mediator release in nasal secretions after nasal challenge with cypress pollens. | 2004 | Allergy | pmid:15230820 |
Crampette L et al. | Inhibition of mediator and cytokine release from dispersed nasal polyp cells by terfenadine. | 1996 | Allergy | pmid:8836342 |
Zuberbier T et al. | Histamine releasability of basophils and skin mast cells in chronic urticaria. | 1996 | Allergy | pmid:8721524 |
Gurzeler U et al. | In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8. | 2013 | Allergy | pmid:23590216 |
Wang DY et al. | The upper and lower airway responses to nasal challenge with house-dust mite Blomia tropicalis. | 2003 | Allergy | pmid:12580812 |
Takafuji S et al. | Release of granule proteins from human eosinophils stimulated with mast-cell mediators. | 1998 | Allergy | pmid:9821474 |
Schauer U et al. | Blood eosinophils, eosinophil-derived proteins, and leukotriene C4 generation in relation to bronchial hyperreactivity in children with atopic dermatitis. | 1995 | Allergy | pmid:7604934 |
Taskila K et al. | Histamine and LTC4 in stinging nettle-induced urticaria. | 2000 | Allergy | pmid:10921474 |