LTC4

Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.

Cross Reference

Introduction

To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with LTC4?

LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with LTC4

MeSH term MeSH ID Detail
Bronchial Hyperreactivity D016535 15 associated lipids
Ulcer D014456 16 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Leukemia, Myelogenous, Chronic, BCR-ABL Positive D015464 17 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Cough D003371 19 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Carcinoma, Small Cell D018288 21 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with LTC4

Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with LTC4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with LTC4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with LTC4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with LTC4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with LTC4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with LTC4

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Authors Title Published Journal PubMed Link
Sabbah A et al. [Anaphylactic or anaphylactoid reactions to paracetamol. Report of 3 cases]. 1997 Allerg Immunol (Paris) pmid:9221011
Sabbah A et al. [Testing basophil activation by flow cytometry in the diagnosis of allergy to hymenopteran venom]. 1998 Allerg Immunol (Paris) pmid:9559061
Sainte-Laudy J et al. [Importance of the leukotriene C4 liberation test for the diagnosis of drug allergy (preliminary results)]. 1996 Allerg Immunol (Paris) pmid:8703308
Collin N et al. [Search for a threshold to distinguish between locoregional and systemic reactions using the histamine liberation value and the LTC4 level]. 1999 Allerg Immunol (Paris) pmid:10070593
Venière A et al. [Importance of blood tests for the diagnosis of drug allergies]. 2000 Allerg Immunol (Paris) pmid:10971854
Karaman O et al. The comparison of the efficacy of fluticasone propionate with cetirizine in perennial allergic rhinitis. 2001 Mar-Apr Allergol Immunopathol (Madr) pmid:11420028
Pereira-Vega A et al. Premenstrual asthma and leukotriene variations in the menstrual cycle. 2012 Nov-Dec Allergol Immunopathol (Madr) pmid:22115570
Horak F et al. Effect of continuous allergen challenge on clinical symptoms and mediator release in dust-mite-allergic patients. 1998 Allergy pmid:9491231
Zuberbier T et al. Histamine releasability of basophils and skin mast cells in chronic urticaria. 1996 Allergy pmid:8721524
Taskila K et al. Histamine and LTC4 in stinging nettle-induced urticaria. 2000 Allergy pmid:10921474