LTC4

Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.

Cross Reference

Introduction

To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with LTC4?

LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with LTC4

MeSH term MeSH ID Detail
Autoimmune Diseases D001327 27 associated lipids
Angina Pectoris D000787 27 associated lipids
Gastritis D005756 27 associated lipids
Nasal Polyps D009298 26 associated lipids
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Carcinoma, Small Cell D018288 21 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Cough D003371 19 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with LTC4

Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with LTC4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with LTC4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with LTC4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with LTC4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with LTC4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with LTC4

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Authors Title Published Journal PubMed Link
Renić M et al. The effect of interleukin 1 alpha on acetaminophen-induced hepatotoxicity. 1993 Cytokine pmid:8218930
Kohrogi H et al. Release of tachykinins and its metabolism in the airway. 1993 Regul. Pept. pmid:8210488
Devalia JL et al. Human bronchial epithelial cell dysfunction following in vitro exposure to nitrogen dioxide. 1993 Eur. Respir. J. pmid:8287947
MacGlashan DW and Hubbard WC IL-3 alters free arachidonic acid generation in C5a-stimulated human basophils. 1993 J. Immunol. pmid:8245471
Mita H et al. Purification of human blood basophils and leukotriene C4 generation following calcium ionophore stimulation. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:7505057
Mifune T et al. Chemical mediator and cellular reaction in the bronchoalveolar lavage fluid of patients with steroid-dependent intractable asthma (SDIA). 1993 Acta Med. Okayama pmid:7505996
Marone G et al. Anti-inflammatory effects of glucocorticoids and cyclosporin A on human basophils. 1993 Eur. J. Clin. Pharmacol. pmid:7508864
Lee TH and Christie PE Leukotrienes and aspirin induced asthma. 1993 Thorax pmid:8303620
Dahlén B et al. Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects. 1993 Thorax pmid:8303624
Westcott JY et al. Inactivation of peptidoleukotrienes in the isolated perfused rat lung. 1993 Arch. Biochem. Biophys. pmid:7692821