| MeSH term | MeSH ID | Detail |
|---|---|---|
| Rhinitis, Allergic, Seasonal | D006255 | 7 associated lipids |
| Hyperbilirubinemia | D006932 | 11 associated lipids |
| Hyperbilirubinemia, Hereditary | D006933 | 3 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Insect Bites and Stings | D007299 | 4 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
LTC4
Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.
Cross Reference
Introduction
To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with LTC4?
LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with LTC4
PubChem Associated disorders and diseases
What pathways are associated with LTC4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with LTC4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with LTC4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with LTC4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with LTC4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with LTC4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with LTC4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nilsen A et al. | Short-term exposure of rodents to diesel exhausts: usefulness for studies of genotoxic and immunotoxic effects. | 1999 | Chem. Biol. Interact. | pmid:10227576 |
| Hamasaki Y et al. | Magnolol inhibits leukotriene synthesis in rat basophilic leukemia-2H3 cells. | 1999 | Planta Med. | pmid:10232065 |
| Denizot Y et al. | Are lipid mediators implicated in the production of pro- and anti-inflammatory cytokines during cardiopulmonary bypass graft with extracorporeal circulation? | 1999 | Cytokine | pmid:10328869 |
| Niinuma K et al. | Primary active transport of organic anions on bile canalicular membrane in humans. | 1999 | Am. J. Physiol. | pmid:10330006 |
| Hipfner DR et al. | Monoclonal antibodies that inhibit the transport function of the 190-kDa multidrug resistance protein, MRP. Localization of their epitopes to the nucleotide-binding domains of the protein. | 1999 | J. Biol. Chem. | pmid:10336431 |
| Sano A et al. | Inhibition of cPLA2 translocation and leukotriene C4 secretion by fluticasone propionate in exogenously activated human eosinophils. | 1999 | Am. J. Respir. Crit. Care Med. | pmid:10351938 |
| Kita H et al. | Does IgE bind to and activate eosinophils from patients with allergy? | 1999 | J. Immunol. | pmid:10352312 |
| Chen ZS et al. | An enhanced active efflux of CPT-11 and SN-38 in cisplatin-resistant human KB carcinoma cells. | 1999 | Cancer Lett. | pmid:10378768 |
| Gibbs BF and Grabbe J | Inhibitors of PI 3-kinase and MEK kinase differentially affect mediator secretion from immunologically activated human basophils. | 1999 | J. Leukoc. Biol. | pmid:10380914 |
| Miadonna A et al. | Nasal response to a single antigen challenge in patients with allergic rhinitis - inflammatory cell recruitment persists up to 48 hours. | 1999 | Clin. Exp. Allergy | pmid:10383595 |
| Vellenga E et al. | Interleukin-6 production by activated human monocytic cells is enhanced by MK-571, a specific inhibitor of the multi-drug resistance protein-1. | 1999 | Br. J. Pharmacol. | pmid:10385244 |
| Lynch KR et al. | Characterization of the human cysteinyl leukotriene CysLT1 receptor. | 1999 | Nature | pmid:10391245 |
| Cordoba-Rodriguez R et al. | Calcium regulation of a slow post-spike hyperpolarization in vagal afferent neurons. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10393875 |
| Bischoff SC et al. | IL-4 enhances proliferation and mediator release in mature human mast cells. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10393951 |
| Clish CB et al. | Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10393980 |
| Irkeç MT et al. | Role of tear inflammatory mediators in contact lens-associated giant papillary conjunctivitis in soft contact lens wearers. | 1999 | Ocul. Immunol. Inflamm. | pmid:10410873 |
| Dantzig AH et al. | Selectivity of the multidrug resistance modulator, LY335979, for P-glycoprotein and effect on cytochrome P-450 activities. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10411602 |
| Rappa G et al. | New insights into the biology and pharmacology of the multidrug resistance protein (MRP) from gene knockout models. | 1999 | Biochem. Pharmacol. | pmid:10413292 |
| Kamisako T et al. | Transport of monoglucuronosyl and bisglucuronosyl bilirubin by recombinant human and rat multidrug resistance protein 2. | 1999 | Hepatology | pmid:10421658 |
| Stride BD et al. | Localization of a substrate specificity domain in the multidrug resistance protein. | 1999 | J. Biol. Chem. | pmid:10428874 |