| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pulmonary Disease, Chronic Obstructive | D029424 | 16 associated lipids |
| Asthma, Exercise-Induced | D001250 | 10 associated lipids |
| Ventricular Remodeling | D020257 | 28 associated lipids |
| Wounds, Nonpenetrating | D014949 | 4 associated lipids |
| Cholestasis, Extrahepatic | D001651 | 7 associated lipids |
| Insect Bites and Stings | D007299 | 4 associated lipids |
| Carotid Artery Injuries | D020212 | 8 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
| Common Bile Duct Diseases | D003137 | 3 associated lipids |
| Cestode Infections | D002590 | 3 associated lipids |
| Neointima | D058426 | 3 associated lipids |
| Asbestosis | D001195 | 8 associated lipids |
| Phlebitis | D010689 | 1 associated lipids |
| Picornaviridae Infections | D010850 | 4 associated lipids |
| Eosinophilic Esophagitis | D057765 | 3 associated lipids |
LTC4
Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.
Cross Reference
Introduction
To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with LTC4?
LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with LTC4
PubChem Associated disorders and diseases
What pathways are associated with LTC4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with LTC4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with LTC4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with LTC4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with LTC4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with LTC4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with LTC4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Medrala W et al. | [Efficacy and safety of specific immunotherapy of upper airways allergic diseases caused by allergy to mites]. | 2006 | Pol. Merkur. Lekarski | pmid:16875150 |
| Leynadier F | [Drug allergies: value of the leucotriene C4 release test?]. | 1997 | Presse Med | pmid:9180883 |
| Mandal AK et al. | The membrane organization of leukotriene synthesis. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15084748 |
| Paul S et al. | ATP-dependent uptake of natural product cytotoxic drugs by membrane vesicles establishes MRP as a broad specificity transporter. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8692921 |
| Goulet JL et al. | Altered inflammatory responses in leukotriene-deficient mice. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7809134 |
| Müller M et al. | Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7809167 |
| Bischoff SC et al. | IL-4 enhances proliferation and mediator release in mature human mast cells. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10393951 |
| Clish CB et al. | Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10393980 |
| Lam BK et al. | Expression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8052639 |
| Janssen-Timmen U et al. | Expression of 5-lipoxygenase in differentiating human skin keratinocytes. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7624354 |