LTC4

Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.

Cross Reference

Introduction

To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with LTC4?

LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with LTC4

MeSH term MeSH ID Detail
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Nasal Polyps D009298 26 associated lipids
Gastritis D005756 27 associated lipids
Angina Pectoris D000787 27 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Drug Eruptions D003875 30 associated lipids
Burns D002056 34 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Glomerulonephritis D005921 35 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with LTC4

Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with LTC4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with LTC4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with LTC4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with LTC4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with LTC4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with LTC4

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Authors Title Published Journal PubMed Link
Le Poole IC et al. Organotypic culture of human skin to study melanocyte migration. 1994 Pigment Cell Res. pmid:8072944
Shimizu T et al. Effects of pancreatic and snake venom phospholipase A2 on the generation of leukotriene B4 and C4 by human leukocytes in vitro. 1994 Pancreas pmid:8108369
Schuil PJ et al. Histamine and leukotriene C4 effects on in vitro ciliary beat frequency of human upper respiratory cilia. 1994 Eur Arch Otorhinolaryngol pmid:7848641
Currie S et al. Phosphorylation and activation of Ca(2+)-sensitive cytosolic phospholipase A2 in MCII mast cells mediated by high-affinity Fc receptor for IgE. 1994 Biochem. J. pmid:7818499
Teshigawara H and Moriya Y The role of leukotriene C4 in biphasic release of histamine from mouse mastocytoma cell line (P-815). 1994 Gen. Pharmacol. pmid:7530673
Chen CR et al. Platelet-activating factor potentiates protamine-induced lung edema. Role of eicosanoids. 1994 Am. J. Respir. Crit. Care Med. pmid:8111595
Büyükgebiz O et al. Captopril increases endothelin serum concentrations and preserves intestinal mucosa after mesenteric ischemia-reperfusion injury. 1994 Res Exp Med (Berl) pmid:7536337
Ramis I et al. Application of totally automated on-line sample clean up system for extraction and high-performance liquid chromatography separation of peptide leukotrienes. 1993 Nov-Dec J Pharm Biomed Anal pmid:8123725
Sichletidis L et al. Comparative efficacy of salbutamol and salmeterol in exercise-induced asthma. 1993 Mar-Apr J. Int. Med. Res. pmid:8243793
Casolaro V et al. Nimesulide, a sulfonanilide nonsteroidal anti-inflammatory drug, inhibits mediator release from human basophils and mast cells. 1993 J. Pharmacol. Exp. Ther. pmid:7505332