| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pneumococcal Infections | D011008 | 7 associated lipids |
| Eosinophilia | D004802 | 4 associated lipids |
| Coronary Artery Disease | D003324 | 47 associated lipids |
| Cough | D003371 | 19 associated lipids |
| Dermatitis, Atopic | D003876 | 19 associated lipids |
| Status Asthmaticus | D013224 | 4 associated lipids |
| Pseudoxanthoma Elasticum | D011561 | 2 associated lipids |
| Rhinitis, Allergic, Perennial | D012221 | 6 associated lipids |
| Acute-Phase Reaction | D000210 | 12 associated lipids |
| Uveitis | D014605 | 14 associated lipids |
LTC4
Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.
Cross Reference
Introduction
To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with LTC4?
LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with LTC4
PubChem Associated disorders and diseases
What pathways are associated with LTC4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with LTC4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with LTC4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with LTC4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with LTC4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with LTC4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with LTC4
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|---|---|---|---|---|
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| Zuany-Amorim C et al. | Strain-dependency of leukotriene C4 generation from isolated lungs of immunized mice. | 1994 | Br. J. Pharmacol. | pmid:7524994 |
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| Teshigawara H and Moriya Y | The role of leukotriene C4 in biphasic release of histamine from mouse mastocytoma cell line (P-815). | 1994 | Gen. Pharmacol. | pmid:7530673 |
| Leff AR | Inflammatory mediation of airway hyperresponsiveness by peripheral blood granulocytes. The case for the eosinophil. | 1994 | Chest | pmid:7924496 |
| Leier I et al. | Characterization of the ATP-dependent leukotriene C4 export carrier in mastocytoma cells. | 1994 | Eur. J. Biochem. | pmid:8125120 |
| Büchler M et al. | Functional reconstitution of ATP-dependent transporters from the solubilized hepatocyte canalicular membrane. | 1994 | Eur. J. Biochem. | pmid:7925347 |
| O'Neil GS et al. | Effect of surgical preparation and arterialization on vasomotion of human saphenous vein. | 1994 | J. Thorac. Cardiovasc. Surg. | pmid:8127099 |
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| Anwar AR et al. | Adhesion to fibronectin primes eosinophils via alpha 4 beta 1 (VLA-4). | 1994 | Immunology | pmid:7927493 |
| Fujii R et al. | Adenosine triphosphate-dependent transport of leukotriene C4 by membrane vesicles prepared from cisplatin-resistant human epidermoid carcinoma tumor cells. | 1994 | J. Natl. Cancer Inst. | pmid:7966417 |
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| Büyükgebiz O et al. | Captopril increases endothelin serum concentrations and preserves intestinal mucosa after mesenteric ischemia-reperfusion injury. | 1994 | Res Exp Med (Berl) | pmid:7536337 |
| Petric R and Ford-Hutchinson AW | Elevated cysteinyl leukotriene excretion in experimental glomerulonephritis. | 1994 | Kidney Int. | pmid:7853790 |
| Leier I et al. | The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates. | 1994 | J. Biol. Chem. | pmid:7961706 |
| Miadonna A et al. | Modulation of allergen-induced nasal symptoms and mediator release by treatment with N-acetyl-aspartyl-glutamate (ZY15106). | 1994 | Eur. J. Clin. Pharmacol. | pmid:7518775 |
| Yamamura H et al. | Endothelin-1 induces release of histamine and leukotriene C4 from mouse bone marrow-derived mast cells. | 1994 | Eur. J. Pharmacol. | pmid:7522171 |
| Tsopanoglou NE et al. | Leukotrienes C4 and D4 promote angiogenesis via a receptor-mediated interaction. | 1994 | Eur. J. Pharmacol. | pmid:7523148 |
| Tedeschi A et al. | Nasal eosinophilia induced by PAF-acether is accompanied by the release of eosinophil cationic protein. | 1994 | Eur. Respir. J. | pmid:7525344 |
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| Matsumoto T et al. | Effects of diet on experimentally induced intestinal ulcers in rats: morphology and tissue leukotrienes. | 1994 | Gut | pmid:7926906 |
| Shimizu T et al. | Inhibitory effects of theophylline, terbutaline, and hydrocortisone on leukotriene B4 and C4 generation by human leukocytes in vitro. | 1994 | Pediatr. Pulmonol. | pmid:7800427 |
| Scadding GK et al. | Effect of short-term treatment with fluticasone propionate nasal spray on the response to nasal allergen challenge. | 1994 | Br J Clin Pharmacol | pmid:7893587 |
| Ishii K et al. | A useful method for differential evaluation of anti-inflammatory effects due to cyclooxygenase and 5-lipoxygenase inhibitions in mice. | 1994 | Jpn. J. Pharmacol. | pmid:7990266 |
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| Casellas F et al. | Abnormal leukotriene C4 released by unaffected jejunal mucosa in patients with inactive Crohn's disease. | 1994 | Gut | pmid:8174991 |
| Black KL et al. | Enzymatic barrier protects brain capillaries from leukotriene C4. | 1994 | J. Neurosurg. | pmid:7931622 |
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| Christie PE et al. | Increased urinary LTE4 excretion following inhalation of LTC4 and LTE4 in asthmatic subjects. | 1994 | Eur. Respir. J. | pmid:8050548 |
| Laviolette M et al. | Effects of inhaled steroids on blood eosinophils in moderate asthma. | 1994 | Ann. N. Y. Acad. Sci. | pmid:8031001 |
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| Bando T et al. | Inhibitory effect of aerosol administration of a sulfidopeptide leukotriene antagonist on bronchoconstriction induced by antigen inhalation in guinea pigs. | 1994 | Arzneimittelforschung | pmid:8053975 |
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| Böhme M et al. | Cholestasis caused by inhibition of the adenosine triphosphate-dependent bile salt transport in rat liver. | 1994 | Gastroenterology | pmid:8020669 |
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| Amon U et al. | Control function of protein kinase C isozymes on leukotriene generation from human basophils? | 1994 | Agents Actions | pmid:7976816 |
| Medina L et al. | Leukotriene C4 upregulates collagenase expression and synthesis in human lung fibroblasts. | 1994 | Biochim. Biophys. Acta | pmid:7981229 |