LTC4

Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.

Cross Reference

Introduction

To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with LTC4?

LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with LTC4

MeSH term MeSH ID Detail
Anaphylaxis D000707 35 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Peritonitis D010538 38 associated lipids
Arthritis D001168 41 associated lipids
Hypotension D007022 41 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Osteosarcoma D012516 50 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with LTC4

Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with LTC4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with LTC4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with LTC4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with LTC4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with LTC4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with LTC4

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Authors Title Published Journal PubMed Link
Brandenburg K et al. Conformation and fluidity of endotoxins as determinants of biological activity. 1995 Prog. Clin. Biol. Res. pmid:8524923
Willburger RE et al. Inhibition of eicosanoid release from synovial organ culture by incubation with tepoxalin and its acid metabolite. 1996 Prostaglandins pmid:8936587
Hisamatsu K et al. Effect of leukotriene C4 exposure on ciliated cells of the nasal mucosa. 1996 Prostaglandins pmid:8900445
Herman CA et al. Leukotriene C4-stimulated contractions in bullfrog lung are affected by cold acclimation and calcium antagonists. 1995 Prostaglandins pmid:7480797
Baker SR et al. The pharmacology of N-methyl LTC4; a metabolically stable LTC4-mimetic. 1990 Prostaglandins pmid:2255765
Ramondt J et al. Sensitivity of ovine myometrial tissue to various eicosanoids in vitro. 1995 Prostaglandins pmid:7792392
Kitaura K et al. Effects of organic anions and bile acid conjugates on biliary excretion of LTC4 in the rat. 1997 Prostaglandins pmid:9491205
Tanaka H et al. The effect of a novel leukotriene C4/D4 antagonist, BAY-x-7195, on experimental allergic reactions. 1995 Nov-Dec Prostaglandins pmid:8838238
Bandeira-Melo C and Weller PF Eosinophils and cysteinyl leukotrienes. 2003 Aug-Sep Prostaglandins Leukot. Essent. Fatty Acids pmid:12895596
Aktan AO et al. Does PGE2 act as a mediator for endothelin release? 1994 Prostaglandins Leukot. Essent. Fatty Acids pmid:7511821