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Use of zafirlucast, cysteine-containing leukotriene antagonist, in epinephrine-induced heart injury. |
2002 |
Bull. Exp. Biol. Med. |
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Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6). |
2002 |
J. Biol. Chem. |
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2002 |
Vitam. Horm. |
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Delineating the contribution of secretory transporters in the efflux of etoposide using Madin-Darby canine kidney (MDCK) cells overexpressing P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1), and canalicular multispecific organic anion transporter (cMOAT). |
2002 |
Drug Metab. Dispos. |
pmid:11901101
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Malaviya R and Uckun FM |
Role of STAT6 in IgE receptor/FcepsilonRI-mediated late phase allergic responses of mast cells. |
2002 |
J. Immunol. |
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Miller DS et al. |
Xenobiotic efflux pumps in isolated fish brain capillaries. |
2002 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
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Pharmacological differences among CysLT(1) receptor antagonists with respect to LTC(4) and LTD(4) in human lung parenchyma. |
2002 |
Biochem. Pharmacol. |
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IL-16 promotes leukotriene C(4) and IL-4 release from human eosinophils via CD4- and autocrine CCR3-chemokine-mediated signaling. |
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J. Immunol. |
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Determinants of the substrate specificity of multidrug resistance protein 1: role of amino acid residues with hydrogen bonding potential in predicted transmembrane helix 17. |
2002 |
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Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses. |
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Distinct roles of receptor phosphorylation, G protein usage, and mitogen-activated protein kinase activation on platelet activating factor-induced leukotriene C(4) generation and chemokine production. |
2002 |
J. Biol. Chem. |
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Adhesion-dependent interactions between eosinophils and cholinergic nerves. |
2002 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
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Am. J. Physiol. Lung Cell Mol. Physiol. |
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2002 |
J. Immunol. |
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GSH-dependent photolabeling of multidrug resistance protein MRP1 (ABCC1) by [125I]LY475776. Evidence of a major binding site in the COOH-proximal membrane spanning domain. |
2002 |
J. Biol. Chem. |
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A naturally occurring mutation in MRP1 results in a selective decrease in organic anion transport and in increased doxorubicin resistance. |
2002 |
Pharmacogenetics |
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Role of the N-terminal transmembrane region of the multidrug resistance protein MRP2 in routing to the apical membrane in MDCKII cells. |
2002 |
J. Biol. Chem. |
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Increased responsiveness of murine eosinophils to MIP-1beta (CCL4) and TCA-3 (CCL1) is mediated by their specific receptors, CCR5 and CCR8. |
2002 |
J. Leukoc. Biol. |
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Nobata K et al. |
Alpha(1L)-, but not alpha(1H)-, adrenoceptor antagonist prevents allergic bronchoconstriction in guinea pigs in vivo. |
2002 |
Eur. J. Pharmacol. |
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Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1. |
2002 |
J. Biol. Chem. |
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Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1. |
2002 |
J. Biol. Chem. |
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2002 |
J. Exp. Med. |
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A high-throughput assay for measurement of multidrug resistance protein-mediated transport of leukotriene C4 into membrane vesicles. |
2002 |
Anal. Biochem. |
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Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6). |
2002 |
Cancer Res. |
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The contraction of the human pulmonary artery by LTC4 is resistant to cysLT1 antagonists and counteracted by prostacyclin release. |
2002 |
Adv. Exp. Med. Biol. |
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Cultured human intestinal mast cells express functional IL-3 receptors and respond to IL-3 by enhancing growth and IgE receptor-dependent mediator release. |
2002 |
Eur. J. Immunol. |
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Clinical and genetic features underlying the response of patients with bronchial asthma to treatment with a leukotriene receptor antagonist. |
2002 |
Eur. J. Clin. Invest. |
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Functional analysis of ABCA8, a new drug transporter. |
2002 |
Biochem. Biophys. Res. Commun. |
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Suzuki Y et al. |
Silver activates calcium signals in rat basophilic leukemia-2H3 mast cells by a mechanism that differs from the Fc epsilon RI-activated response. |
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J. Immunol. |
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Membrane localization and topology of leukotriene C4 synthase. |
2002 |
J. Biol. Chem. |
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Malaviya R and Uckun FM |
Leflunomide metabolite analogue alpha-cyano-beta-hydroxy-beta-methyl-N-[3-(trifluoromethyl)phenyl]propenamide inhibits IgE/FcepsilonRI receptor-mediated mast cell leukotriene release and allergic asthma in mice. |
2001 Sep-Oct |
Am J Ther |
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Tirofiban administration attenuates platelet and platelet-neutrophil conjugation but not neutrophil degranulation during in vitro VAD circulation. |
2001 May-Jun |
ASAIO J. |
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The comparison of the efficacy of fluticasone propionate with cetirizine in perennial allergic rhinitis. |
2001 Mar-Apr |
Allergol Immunopathol (Madr) |
pmid:11420028
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Abeywardena MY et al. |
Dietary n-3 and n-6 polyunsaturated oils and airway contractility. |
2001 Apr-May |
Prostaglandins Leukot. Essent. Fatty Acids |
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Changes of gut barrier function during anesthesia and cardiac surgery. |
2001 |
Angiology |
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Effects of furocoumarins from Cachrys trifida on some macrophage functions. |
2001 |
J. Pharm. Pharmacol. |
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Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity. |
2001 |
J. Biol. Chem. |
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Inhibitory effects of helenalin and related compounds on 5-lipoxygenase and leukotriene C(4) synthase in human blood cells. |
2001 |
Biochem. Pharmacol. |
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Localizing a control region in the pathway to leukotriene C(4) secretion following stimulation of human basophils with anti-IgE antibody. |
2001 |
J. Immunol. |
pmid:11739523
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Gurish MF and Austen KF |
The diverse roles of mast cells. |
2001 |
J. Exp. Med. |
pmid:11435478
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Effects of six diterpenes on macrophage eicosanoid biosynthesis. |
2001 |
Life Sci. |
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Cysteinyl leukotriene receptor assays. |
2001 |
Curr Protoc Pharmacol |
pmid:22293965
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Molecular cloning and functional characterization of murine cysteinyl-leukotriene 1 (CysLT(1)) receptors. |
2001 |
Biochem. Pharmacol. |
pmid:11705452
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Fukuishi N et al. |
Antiallergic effect of ardisiaquinone A, a potent 5-lipoxygenase inhibitor. |
2001 |
Phytomedicine |
pmid:11824521
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Role of chemical mediators in airway hyperresponsiveness in an asthmatic model. |
2001 |
Respiration |
pmid:11223734
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Setoguchi H et al. |
Leukotriene C(4) enhances the contraction of porcine tracheal smooth muscle through the activation of Y-27632, a rho kinase inhibitor, sensitive pathway. |
2001 |
Br. J. Pharmacol. |
pmid:11156567
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Amann R et al. |
Effects of COX-1 and COX-2 inhibitors on eicosanoid biosynthesis and the release of substance P from the guinea-pig isolated perfused lung. |
2001 |
Inflamm. Res. |
pmid:11235022
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Selectivity of recombinant human leukotriene D(4), leukotriene B(4), and lipoxin A(4) receptors with aspirin-triggered 15-epi-LXA(4) and regulation of vascular and inflammatory responses. |
2001 |
Am. J. Pathol. |
pmid:11141472
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Picado C and Valero A |
COX-1 sparing drugs in aspirin-sensitive asthma. |
2001 |
Clin. Exp. Allergy |
pmid:11251618
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Terlouw SA et al. |
Role of multidrug resistance protein 2 (MRP2) in glutathione-bimane efflux from Caco-2 and rat renal proximal tubule cells. |
2001 |
Br. J. Pharmacol. |
pmid:11682439
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