| MeSH term | MeSH ID | Detail |
|---|---|---|
| Periapical Periodontitis | D010485 | 6 associated lipids |
| Bronchial Hyperreactivity | D016535 | 15 associated lipids |
| Angina Pectoris | D000787 | 27 associated lipids |
| Hyperbilirubinemia, Hereditary | D006933 | 3 associated lipids |
| Rhinitis, Allergic, Seasonal | D006255 | 7 associated lipids |
| Drug Eruptions | D003875 | 30 associated lipids |
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
| Mesenteric Vascular Occlusion | D008641 | 4 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Leukemia-Lymphoma, Adult T-Cell | D015459 | 25 associated lipids |
LTC4
Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.
Cross Reference
Introduction
To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with LTC4?
LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with LTC4
PubChem Associated disorders and diseases
What pathways are associated with LTC4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with LTC4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with LTC4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with LTC4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with LTC4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with LTC4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with LTC4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Huang SC | Leukotriene-induced contraction is mediated by cysteinyl leukotriene receptor CysLT1 in guinea pig fundus but by CysLT1 and CysLT2 in antrum. | 2011 | Life Sci. | pmid:21396378 |
| Hung ND et al. | Oral administration of 2-docosahexaenoyl lysophosphatidylcholine displayed anti-inflammatory effects on zymosan A-induced peritonitis. | 2011 | Inflammation | pmid:20490641 |
| Mesquita-Santos FP et al. | Co-operative signalling through DP(1) and DP(2) prostanoid receptors is required to enhance leukotriene C(4) synthesis induced by prostaglandin D(2) in eosinophils. | 2011 | Br. J. Pharmacol. | pmid:20973774 |
| He P et al. | Oxidative stress suppresses cysteinyl leukotriene generation by mouse bone marrow-derived mast cells. | 2011 | J. Biol. Chem. | pmid:21233206 |
| Aung G et al. | Catestatin, a neuroendocrine antimicrobial peptide, induces human mast cell migration, degranulation and production of cytokines and chemokines. | 2011 | Immunology | pmid:21214543 |
| Oh YC et al. | Anti-allergic effects of sinomenine by inhibition of prostaglandin Dâ‚‚ and leukotriene Câ‚„ in mouse bone marrow-derived mast cells. | 2011 | Immunopharmacol Immunotoxicol | pmid:21080779 |
| Hung ND et al. | Mechanisms for anti-inflammatory effects of 1-[15(S)-hydroxyeicosapentaenoyl] lysophosphatidylcholine, administered intraperitoneally, in zymosan A-induced peritonitis. | 2011 | Br. J. Pharmacol. | pmid:21091644 |
| Dartt DA et al. | Conjunctival goblet cell secretion stimulated by leukotrienes is reduced by resolvins D1 and E1 to promote resolution of inflammation. | 2011 | J. Immunol. | pmid:21357260 |
| Borrelli I et al. | Benzene metabolites inhibit the release of proinflammatory mediators and cytokines from human basophils. | 2010 Jul-Sep | Int J Immunopathol Pharmacol | pmid:20943043 |
| Lin TY and London CA | Characterization and modulation of canine mast cell derived eicosanoids. | 2010 | Vet. Immunol. Immunopathol. | pmid:20036014 |
| Korzekwa A et al. | Leukotrienes are auto-/paracrine factors in the bovine corpus luteum: an in vitro study. | 2010 | Reprod. Domest. Anim. | pmid:19645858 |
| Silva RC et al. | Leukotrienes produced in allergic lung inflammation activate alveolar macrophages. | 2010 | Cell. Physiol. Biochem. | pmid:20798516 |
| Quan Z et al. | Ethanol extracts of Saururus chinensis suppress ovalbumin-sensitization airway inflammation. | 2010 | J Ethnopharmacol | pmid:20699114 |
| Lee SJ et al. | 4-Hydroxynonenal enhances MMP-9 production in murine macrophages via 5-lipoxygenase-mediated activation of ERK and p38 MAPK. | 2010 | Toxicol. Appl. Pharmacol. | pmid:19837106 |
| Chebolu S et al. | Pranlukast prevents cysteinyl leukotriene-induced emesis in the least shrew (Cryptotis parva). | 2010 | Eur. J. Pharmacol. | pmid:19941848 |
| Zhang T et al. | Pharmacology and immunological actions of a herbal medicine ASHMI on allergic asthma. | 2010 | Phytother Res | pmid:19998324 |
| Kawamura F et al. | Effects of menadione, a reactive oxygen generator, on leukotriene secretion from RBL-2H3 cells. | 2010 | Biol. Pharm. Bull. | pmid:20460770 |
| Oh YC et al. | Anti-allergic activity of a platycodon root ethanol extract. | 2010 | Int J Mol Sci | pmid:20717534 |
| Korzekwa AJ et al. | Leukotrienes modulate secretion of progesterone and prostaglandins during the estrous cycle and early pregnancy in cattle: an in vivo study. | 2010 | Reproduction | pmid:20813877 |
| Black AT et al. | Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide. | 2010 | Toxicol. Appl. Pharmacol. | pmid:20840853 |