Chrubasik S et al. |
Harpagophytum extracts. |
2002 |
Clin. Pharmacol. Ther. |
pmid:11823764
|
Bermejo BP et al. |
Sesquiterpenes from Jasonia glutinosa: in vitro anti-inflammatory activity. |
2002 |
Biol. Pharm. Bull. |
pmid:11824534
|
Shon YH et al. |
Effect of Astragali radix extract on lipopolysaccharide-induced inflammation in human amnion. |
2002 |
Biol. Pharm. Bull. |
pmid:11824562
|
Bäck M et al. |
Modulation of vascular tone and reactivity by nitric oxide in porcine pulmonary arteries and veins. |
2002 |
Acta Physiol. Scand. |
pmid:11851592
|
Küsters S et al. |
Effects of antihistamines on leukotriene and cytokine release from dispersed nasal polyp cells. |
2002 |
Arzneimittelforschung |
pmid:11878205
|
Iliás A et al. |
Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6). |
2002 |
J. Biol. Chem. |
pmid:11880368
|
Jedlitschky G and Keppler D |
Transport of leukotriene C4 and structurally related conjugates. |
2002 |
Vitam. Horm. |
pmid:11898391
|
Oliveira SH et al. |
Stem cell factor induces eosinophil activation and degranulation: mediator release and gene array analysis. |
2002 |
Blood |
pmid:12453875
|
Suzuki R and Freed AN |
Heparin inhibits hyperventilation-induced late-phase hyperreactivity in dogs. |
2002 |
Am. J. Respir. Crit. Care Med. |
pmid:11779726
|
Guo A et al. |
Delineating the contribution of secretory transporters in the efflux of etoposide using Madin-Darby canine kidney (MDCK) cells overexpressing P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1), and canalicular multispecific organic anion transporter (cMOAT). |
2002 |
Drug Metab. Dispos. |
pmid:11901101
|
Malaviya R and Uckun FM |
Role of STAT6 in IgE receptor/FcepsilonRI-mediated late phase allergic responses of mast cells. |
2002 |
J. Immunol. |
pmid:11751988
|
Miller DS et al. |
Xenobiotic efflux pumps in isolated fish brain capillaries. |
2002 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:11742838
|
Ohashi M et al. |
Effects of phalloidin on the biliary excretion of cholephilic compounds in rats. |
2002 |
Pharmacology |
pmid:12169763
|
Arango P and Kountakis SE |
Presence of cysteinyl leukotrienes in asthmatic patients with chronic sinusitis. |
2002 |
Laryngoscope |
pmid:12169896
|
Gibbs BF et al. |
Regulation of mediator secretion in human basophils by p38 mitogen-activated protein kinase: phosphorylation is sensitive to the effects of phosphatidylinositol 3-kinase inhibitors and calcium mobilization. |
2002 |
J. Leukoc. Biol. |
pmid:12149431
|
Hashizume K and Black KL |
Increased endothelial vesicular transport correlates with increased blood-tumor barrier permeability induced by bradykinin and leukotriene C4. |
2002 |
J. Neuropathol. Exp. Neurol. |
pmid:12152787
|
Haimeur A et al. |
Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity. |
2002 |
J. Biol. Chem. |
pmid:12186871
|
Norman BH et al. |
Tricyclic isoxazoles are novel inhibitors of the multidrug resistance protein (MRP1). |
2002 |
Bioorg. Med. Chem. Lett. |
pmid:11958985
|
Kolaczkowska E et al. |
Early vascular permeability in murine experimental peritonitis is co-mediated by resident peritoneal macrophages and mast cells: crucial involvement of macrophage-derived cysteinyl-leukotrienes. |
2002 |
Inflammation |
pmid:11989789
|
Ravasi S et al. |
Pharmacological differences among CysLT(1) receptor antagonists with respect to LTC(4) and LTD(4) in human lung parenchyma. |
2002 |
Biochem. Pharmacol. |
pmid:11996896
|
Bandeira-Melo C et al. |
IL-16 promotes leukotriene C(4) and IL-4 release from human eosinophils via CD4- and autocrine CCR3-chemokine-mediated signaling. |
2002 |
J. Immunol. |
pmid:11971026
|
Zhang DW et al. |
Determinants of the substrate specificity of multidrug resistance protein 1: role of amino acid residues with hydrogen bonding potential in predicted transmembrane helix 17. |
2002 |
J. Biol. Chem. |
pmid:11925441
|
Maekawa A et al. |
Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses. |
2002 |
J. Biol. Chem. |
pmid:11932261
|
Ahamed J and Ali H |
Distinct roles of receptor phosphorylation, G protein usage, and mitogen-activated protein kinase activation on platelet activating factor-induced leukotriene C(4) generation and chemokine production. |
2002 |
J. Biol. Chem. |
pmid:11934880
|
Kingham PJ et al. |
Adhesion-dependent interactions between eosinophils and cholinergic nerves. |
2002 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12003778
|
Sawatzky DA et al. |
Eosinophil adhesion to cholinergic nerves via ICAM-1 and VCAM-1 and associated eosinophil degranulation. |
2002 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12003784
|
Thomas LL et al. |
Immobilized lactoferrin is a stimulus for eosinophil activation. |
2002 |
J. Immunol. |
pmid:12097406
|
Mao Q et al. |
GSH-dependent photolabeling of multidrug resistance protein MRP1 (ABCC1) by [125I]LY475776. Evidence of a major binding site in the COOH-proximal membrane spanning domain. |
2002 |
J. Biol. Chem. |
pmid:12034727
|
Conrad S et al. |
A naturally occurring mutation in MRP1 results in a selective decrease in organic anion transport and in increased doxorubicin resistance. |
2002 |
Pharmacogenetics |
pmid:12042670
|
Fernández SB et al. |
Role of the N-terminal transmembrane region of the multidrug resistance protein MRP2 in routing to the apical membrane in MDCKII cells. |
2002 |
J. Biol. Chem. |
pmid:12060660
|
Oliveira SH et al. |
Increased responsiveness of murine eosinophils to MIP-1beta (CCL4) and TCA-3 (CCL1) is mediated by their specific receptors, CCR5 and CCR8. |
2002 |
J. Leukoc. Biol. |
pmid:12050188
|
Nobata K et al. |
Alpha(1L)-, but not alpha(1H)-, adrenoceptor antagonist prevents allergic bronchoconstriction in guinea pigs in vivo. |
2002 |
Eur. J. Pharmacol. |
pmid:12323390
|
Koike K et al. |
Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1. |
2002 |
J. Biol. Chem. |
pmid:12388549
|
Yang Y et al. |
Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1. |
2002 |
J. Biol. Chem. |
pmid:12235150
|
Bandeira-Melo C et al. |
Intracrine cysteinyl leukotriene receptor-mediated signaling of eosinophil vesicular transport-mediated interleukin-4 secretion. |
2002 |
J. Exp. Med. |
pmid:12235216
|
Bäck M et al. |
The contraction of the human pulmonary artery by LTC4 is resistant to cysLT1 antagonists and counteracted by prostacyclin release. |
2002 |
Adv. Exp. Med. Biol. |
pmid:12664603
|
Gebhardt T et al. |
Cultured human intestinal mast cells express functional IL-3 receptors and respond to IL-3 by enhancing growth and IgE receptor-dependent mediator release. |
2002 |
Eur. J. Immunol. |
pmid:12209644
|
Mastalerz L et al. |
Clinical and genetic features underlying the response of patients with bronchial asthma to treatment with a leukotriene receptor antagonist. |
2002 |
Eur. J. Clin. Invest. |
pmid:12534456
|
Walch L et al. |
Pharmacological evidence for a novel cysteinyl-leukotriene receptor subtype in human pulmonary artery smooth muscle. |
2002 |
Br. J. Pharmacol. |
pmid:12466244
|
Yang SH et al. |
The stimulatory effects of nasal discharge from patients with perennial allergic rhinitis on normal human neutrophils are normalized after treatment with a new mixed formula of Chinese herbs. |
2002 |
Int. Immunopharmacol. |
pmid:12469937
|
Neu IS et al. |
Leukotrienes in patients with clinically active multiple sclerosis. |
2002 |
Acta Neurol. Scand. |
pmid:11903112
|
Ren XQ et al. |
A positively charged amino acid proximal to the C-terminus of TM17 of MRP1 is indispensable for GSH-dependent binding of substrates and for transport of LTC4. |
2002 |
Biochemistry |
pmid:12450376
|
Ma L et al. |
Identification and characterization of the canine multidrug resistance-associated protein. |
2002 |
Mol. Cancer Ther. |
pmid:12516967
|
Wiklund CU et al. |
Interactions of volatile anesthetics with cholinergic, tachykinin, and leukotriene mechanisms in isolated Guinea pig bronchial smooth muscle. |
2002 |
Anesth. Analg. |
pmid:12456432
|
Tsuruoka S et al. |
Functional analysis of ABCA8, a new drug transporter. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12379217
|
Sakata K and Bäck M |
Receptor preferences of cysteinyl-leukotrienes in the guinea pig lung parenchyma. |
2002 |
Eur. J. Pharmacol. |
pmid:11834255
|
Suzuki Y et al. |
Silver activates calcium signals in rat basophilic leukemia-2H3 mast cells by a mechanism that differs from the Fc epsilon RI-activated response. |
2002 |
J. Immunol. |
pmid:12244196
|
Bandeira-Melo C et al. |
Cysteinyl leukotrienes induce IL-4 release from cord blood-derived human eosinophils. |
2002 |
J. Allergy Clin. Immunol. |
pmid:12063527
|
Christmas P et al. |
Membrane localization and topology of leukotriene C4 synthase. |
2002 |
J. Biol. Chem. |
pmid:12023288
|
ten Hove T et al. |
Differential susceptibility of multidrug resistance protein-1 deficient mice to DSS and TNBS-induced colitis. |
2002 |
Dig. Dis. Sci. |
pmid:12353855
|
Vargaftig BB and Singer M |
Leukotrienes mediate part of Ova-induced lung effects in mice via EGFR. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12794006
|
Vargaftig BB and Singer M |
Leukotrienes mediate murine bronchopulmonary hyperreactivity, inflammation, and part of mucosal metaplasia and tissue injury induced by recombinant murine interleukin-13. |
2003 |
Am. J. Respir. Cell Mol. Biol. |
pmid:12654629
|
Zhu X et al. |
Structural determinants of blockade of eosinophil activation, adhesion and secretion by synthetic analogs of phomactin. |
2003 |
Life Sci. |
pmid:14519449
|
Westlake CJ et al. |
Identification of the structural and functional boundaries of the multidrug resistance protein 1 cytoplasmic loop 3. |
2003 |
Biochemistry |
pmid:14640677
|
Shon YH and Nam KS |
Protective effect of Astragali radix extract on interleukin 1beta-induced in fl ammation in human amnion. |
2003 |
Phytother Res |
pmid:14595579
|
Myou S et al. |
Activation of group IV cytosolic phospholipase A2 in human eosinophils by phosphoinositide 3-kinase through a mitogen-activated protein kinase-independent pathway. |
2003 |
J. Immunol. |
pmid:14530366
|
Gentile DA et al. |
Elevations of local leukotriene C4 levels during viral upper respiratory tract infections. |
2003 |
Ann. Allergy Asthma Immunol. |
pmid:14533659
|
Krasnowska M and Medrala W |
[Effect of IFN-gamma on IGE dependent leukotriene generation by peripheral blood leukocytes in patients with chronic allergic rhinitis in vitro]. |
2003 |
Pneumonol Alergol Pol |
pmid:14587429
|
Chen YH et al. |
IFN-alpha inhibits IL-3 priming of human basophil cytokine secretion but not leukotriene C4 and histamine release. |
2003 |
J. Allergy Clin. Immunol. |
pmid:14610485
|
Deng YM et al. |
Coincidental increase of leukotriene B4 between cerebral cortex and lung tissue of sensitized rats. |
2003 |
Acta Pharmacol. Sin. |
pmid:14531949
|
Lee SH and Altenberg GA |
Transport of leukotriene C4 by a cysteine-less multidrug resistance protein 1 (MRP1). |
2003 |
Biochem. J. |
pmid:12398766
|
Llupià J et al. |
Comparative antiallergic effects of second-generation H1-antihistamines ebastine, cetirizine and loratadine in preclinical models. |
2003 |
Arzneimittelforschung |
pmid:12642964
|
Triggiani M et al. |
Secretory phospholipases A2 activate selective functions in human eosinophils. |
2003 |
J. Immunol. |
pmid:12626587
|
Yang R et al. |
ATP binding to the first nucleotide binding domain of multidrug resistance-associated protein plays a regulatory role at low nucleotide concentration, whereas ATP hydrolysis at the second plays a dominant role in ATP-dependent leukotriene C4 transport. |
2003 |
J. Biol. Chem. |
pmid:12783859
|
Muñoz NM et al. |
Human group V phospholipase A2 induces group IVA phospholipase A2-independent cysteinyl leukotriene synthesis in human eosinophils. |
2003 |
J. Biol. Chem. |
pmid:12796497
|
Dallaire MJ et al. |
Endothelial cells modulate eosinophil surface markers and mediator release. |
2003 |
Eur. Respir. J. |
pmid:12797482
|
Cai Y et al. |
Bronchial mast cells are the dominating LTC4S-expressing cells in aspirin-tolerant asthma. |
2003 |
Am. J. Respir. Cell Mol. Biol. |
pmid:12816731
|
Miller LA et al. |
Glutathione, S-substituted glutathiones, and leukotriene C4 as substrates for peptidylglycine alpha-amidating monooxygenase. |
2003 |
Arch. Biochem. Biophys. |
pmid:12646261
|
Strait RT et al. |
IL-4 exacerbates anaphylaxis. |
2003 |
J. Immunol. |
pmid:12646651
|
Fujisaki T et al. |
Bestatin selectively suppresses the growth of leukemic stem/progenitor cells with BCR/ABL mRNA transcript in patients with chronic myelogeneous leukemia. |
2003 |
Int. Immunopharmacol. |
pmid:12781706
|
Arumugam TV et al. |
Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonist. |
2003 |
Br. J. Pharmacol. |
pmid:12967936
|
Zhang DW et al. |
Functional importance of polar and charged amino acid residues in transmembrane helix 14 of multidrug resistance protein 1 (MRP1/ABCC1): identification of an aspartate residue critical for conversion from a high to low affinity substrate binding state. |
2003 |
J. Biol. Chem. |
pmid:12954620
|
Kowalski ML et al. |
Differential effects of aspirin and misoprostol on 15-hydroxyeicosatetraenoic acid generation by leukocytes from aspirin-sensitive asthmatic patients. |
2003 |
J. Allergy Clin. Immunol. |
pmid:13679808
|
Godinot N et al. |
Cloning and functional characterization of the multidrug resistance-associated protein (MRP1/ABCC1) from the cynomolgus monkey. |
2003 |
Mol. Cancer Ther. |
pmid:12657726
|
Soberman RJ and Christmas P |
The organization and consequences of eicosanoid signaling. |
2003 |
J. Clin. Invest. |
pmid:12697726
|
Reddanna P et al. |
Carboxypeptidase A-catalyzed direct conversion of leukotriene C4 to leukotriene F4. |
2003 |
Arch. Biochem. Biophys. |
pmid:12729612
|
Konno T et al. |
Identification of domains participating in the substrate specificity and subcellular localization of the multidrug resistance proteins MRP1 and MRP2. |
2003 |
J. Biol. Chem. |
pmid:12682044
|
Chibana K et al. |
Up-regulation of cysteinyl leukotriene 1 receptor by IL-13 enables human lung fibroblasts to respond to leukotriene C4 and produce eotaxin. |
2003 |
J. Immunol. |
pmid:12682264
|
Leslie EM et al. |
Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1). |
2003 |
Biochemistry |
pmid:12731862
|
Lee TK et al. |
N-glycosylation controls functional activity of Oatp1, an organic anion transporter. |
2003 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:12702494
|
Venkatachalam TK et al. |
Inhibition of mast cell leukotriene release by thiourea derivatives. |
2003 |
Bioorg. Med. Chem. Lett. |
pmid:12565956
|
Kwak WJ et al. |
Papyriflavonol A from Broussonetia papyrifera inhibits the passive cutaneous anaphylaxis reaction and has a secretory phospholipase A2-inhibitory activity. |
2003 |
Biol. Pharm. Bull. |
pmid:12612436
|
Plath KE et al. |
Calcineurin antagonists differentially affect mediator secretion, p38 mitogen-activated protein kinase and extracellular signal-regulated kinases from immunologically activated human basophils. |
2003 |
Clin. Exp. Allergy |
pmid:12614449
|
Venkatachalam TK et al. |
Substituted heterocyclic thiourea compounds as a new class of anti-allergic agents inhibiting IgE/Fc epsilon RI receptor mediated mast cell leukotriene release. |
2003 |
Bioorg. Med. Chem. |
pmid:12614897
|
Hattori T et al. |
Effects of H2O2 on membrane potential of smooth muscle cells in rabbit mesenteric resistance artery. |
2003 |
Eur. J. Pharmacol. |
pmid:12620501
|
Söderström M et al. |
Expression of leukotriene C4 synthase mRNA by the choroid plexus in mouse brain suggests novel neurohormone functions of cysteinyl leukotrienes. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12878209
|
Zaitsu M et al. |
Dexamethasone accelerates catabolism of leukotriene C4 in bronchial epithelial cells. |
2003 |
Eur. Respir. J. |
pmid:12882448
|
Meliton AY et al. |
Blockade of LTC4 synthesis caused by additive inhibition of gIV-PLA2 phosphorylation: Effect of salmeterol and PDE4 inhibition in human eosinophils. |
2003 |
J. Allergy Clin. Immunol. |
pmid:12897749
|
Chen X et al. |
[Preventive effects of montelukast on hypoxic pulmonary hypertension in rats]. |
2003 |
Sichuan Da Xue Xue Bao Yi Xue Ban |
pmid:12910720
|
Lie WJ et al. |
Regulation and kinetics of platelet-activating factor and leukotriene C4 synthesis by activated human basophils. |
2003 |
Clin. Exp. Allergy |
pmid:12911788
|
Moloney ED et al. |
Release of inflammatory mediators from eosinophils following a hyperosmolar stimulus. |
2003 |
Respir Med |
pmid:12924520
|
Zhang DW et al. |
Characterization of the role of polar amino acid residues within predicted transmembrane helix 17 in determining the substrate specificity of multidrug resistance protein 3. |
2003 |
Biochemistry |
pmid:12924948
|
Payen LF et al. |
Role of carboxylate residues adjacent to the conserved core Walker B motifs in the catalytic cycle of multidrug resistance protein 1 (ABCC1). |
2003 |
J. Biol. Chem. |
pmid:12882957
|
Nunoya K et al. |
Molecular cloning and pharmacological characterization of rat multidrug resistance protein 1 (mrp1). |
2003 |
Drug Metab. Dispos. |
pmid:12867490
|
Tanaka H et al. |
Biliary excretion of phenolphthalein sulfate in rats. |
2003 |
Pharmacology |
pmid:12837971
|
Ichiyama T et al. |
Pranlukast inhibits NF-kappa B activation in human monocytes/macrophages and T cells. |
2003 |
Clin. Exp. Allergy |
pmid:12801316
|
Mizutani N |
[Studies on the experimental allergic rhinitis induced by Japanese cedar pollen--role of cysteinyl leukotrienes in nasal allergic symptoms]. |
2003 |
Yakugaku Zasshi |
pmid:12607939
|
Bouchelouche K et al. |
The cysteinyl-leukotriene D4 induces cytosolic Ca2+ elevation and contraction of the human detrusor muscle. |
2003 |
J. Urol. |
pmid:12853847
|
Nagase T et al. |
A potent inhibitor of cytosolic phospholipase A2, arachidonyl trifluoromethyl ketone, attenuates LPS-induced lung injury in mice. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12505870
|
Vargaftig BB and Singer M |
Leukotrienes, IL-13, and chemokines cooperate to induce BHR and mucus in allergic mouse lungs. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12388339
|