| MeSH term | MeSH ID | Detail |
|---|---|---|
| Angina Pectoris | D000787 | 27 associated lipids |
| Anaphylaxis | D000707 | 35 associated lipids |
| Airway Obstruction | D000402 | 13 associated lipids |
| Acute-Phase Reaction | D000210 | 12 associated lipids |
| Abnormalities, Multiple | D000015 | 13 associated lipids |
LTC4
Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.
Cross Reference
Introduction
To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with LTC4?
LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with LTC4
PubChem Associated disorders and diseases
What pathways are associated with LTC4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with LTC4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with LTC4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with LTC4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with LTC4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with LTC4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with LTC4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Herman CA et al. | Synthesis and action of eicosanoids in warm and cold-acclimated amphibians. | 1997 | Adv. Exp. Med. Biol. | pmid:9561172 |
| Sporn PH et al. | Keratinocyte growth factor increases LTC4 synthesis and expression of flap in cultured rat alveolar type II cells. | 1997 | Adv. Exp. Med. Biol. | pmid:9561179 |
| Kalayci O et al. | LTC4 production by eosinophils in asthmatic subjects with alternative forms of ALOX-5 core promoter. | 2003 | Adv. Exp. Med. Biol. | pmid:12751728 |
| Schweitzer P et al. | Cannabinoid modulation of neuronal activity in adult rat hippocampus. | 1999 | Adv. Exp. Med. Biol. | pmid:10667381 |
| Herman CA and Luczy-Bachman G | Eicosanoids in the brain of warm- and cold-acclimated bullfrogs. | 1999 | Adv. Exp. Med. Biol. | pmid:10667397 |
| Schroeder JT et al. | Human basophils: mediator release and cytokine production. | 2001 | Adv. Immunol. | pmid:11293121 |
| Busse WW and Sedgwick JB | Eosinophil eicosanoid relations in allergic inflammation of the airways. | 1994 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:7771338 |
| Gardiner PJ et al. | Leukotriene receptors and their selective antagonists. | 1994 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:7771349 |
| Keppler D et al. | Transport and metabolism of leukotrienes. | 1994 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:7771352 |
| Lam BK et al. | Expression cloning of human LTC4 synthase. | 1995 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:7732869 |