LTC4

Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.

Cross Reference

Introduction

To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with LTC4?

LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with LTC4

MeSH term MeSH ID Detail
Neointima D058426 3 associated lipids
Asbestosis D001195 8 associated lipids
Phlebitis D010689 1 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Eosinophilic Esophagitis D057765 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with LTC4

Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with LTC4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with LTC4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with LTC4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with LTC4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with LTC4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with LTC4

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Authors Title Published Journal PubMed Link
Keum JH et al. The anti-inflammatory effect of Cheongseoikki-tang ethanol extract on allergic reactions mediated by bone marrow-derived mast cells. 2013 Chin J Integr Med pmid:23494327
Yoo JM et al. Inhibitory effect of N-Acyl dopamines on IgE-mediated allergic response in RBL-2H3 cells. 2013 Lipids pmid:23377981
Ahmad S et al. Catalytic characterization of human microsomal glutathione S-transferase 2: identification of rate-limiting steps. 2013 Biochemistry pmid:23409838
Hirata H et al. Leukotriene C4 aggravates bleomycin-induced pulmonary fibrosis in mice. 2013 Respirology pmid:23432979
Quan GH et al. Anti-allergic flavones from Arthraxon hispidus. 2013 Chem. Pharm. Bull. pmid:23995356
Dong X et al. Urotensin II promotes the production of LTC4 in rat aortic adventitial fibroblasts through NF-κB-5-LO pathway by p38 MAPK and ERK activations. 2013 Heart Vessels pmid:23053343
Cummings HE et al. Cutting edge: Leukotriene C4 activates mouse platelets in plasma exclusively through the type 2 cysteinyl leukotriene receptor. 2013 J. Immunol. pmid:24244016
Pereira-Vega A et al. Premenstrual asthma and leukotriene variations in the menstrual cycle. 2012 Nov-Dec Allergol Immunopathol (Madr) pmid:22115570
Hanjalic-Beck A et al. Chlormadinone acetate suppresses prostaglandin biosynthesis in human endometrial explants. 2012 Fertil. Steril. pmid:22769735
Song HH et al. Anti-inflammatory and anti-allergic effect of Agaricus blazei extract in bone marrow-derived mast cells. 2012 Am. J. Chin. Med. pmid:22928836