LTC4

Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.

Cross Reference

Introduction

To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with LTC4?

LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with LTC4

MeSH term MeSH ID Detail
Phlebitis D010689 1 associated lipids
Pseudoxanthoma Elasticum D011561 2 associated lipids
Eosinophilic Esophagitis D057765 3 associated lipids
Common Bile Duct Diseases D003137 3 associated lipids
Cestode Infections D002590 3 associated lipids
Hyperbilirubinemia, Hereditary D006933 3 associated lipids
Neointima D058426 3 associated lipids
Insect Bites and Stings D007299 4 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Mesenteric Vascular Occlusion D008641 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with LTC4

Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with LTC4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with LTC4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with LTC4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with LTC4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with LTC4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with LTC4

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Authors Title Published Journal PubMed Link
Shimizu T et al. Effects of pancreatic and snake venom phospholipase A2 on the generation of leukotriene B4 and C4 by human leukocytes in vitro. 1994 Pancreas pmid:8108369
Currie S et al. Phosphorylation and activation of Ca(2+)-sensitive cytosolic phospholipase A2 in MCII mast cells mediated by high-affinity Fc receptor for IgE. 1994 Biochem. J. pmid:7818499
Teshigawara H and Moriya Y The role of leukotriene C4 in biphasic release of histamine from mouse mastocytoma cell line (P-815). 1994 Gen. Pharmacol. pmid:7530673
Leier I et al. Characterization of the ATP-dependent leukotriene C4 export carrier in mastocytoma cells. 1994 Eur. J. Biochem. pmid:8125120
Yamamura H et al. Endothelin-1 induces release of histamine and leukotriene C4 from mouse bone marrow-derived mast cells. 1994 Eur. J. Pharmacol. pmid:7522171
Tsopanoglou NE et al. Leukotrienes C4 and D4 promote angiogenesis via a receptor-mediated interaction. 1994 Eur. J. Pharmacol. pmid:7523148
Tedeschi A et al. Nasal eosinophilia induced by PAF-acether is accompanied by the release of eosinophil cationic protein. 1994 Eur. Respir. J. pmid:7525344
Scadding GK et al. Effect of short-term treatment with fluticasone propionate nasal spray on the response to nasal allergen challenge. 1994 Br J Clin Pharmacol pmid:7893587
Laviolette M et al. Effects of inhaled steroids on blood eosinophils in moderate asthma. 1994 Ann. N. Y. Acad. Sci. pmid:8031001
Cotti E and Torabinejad M Detection of leukotriene C4 in human periradicular lesions. 1994 Int Endod J pmid:8034369