| MeSH term | MeSH ID | Detail |
|---|---|---|
| Phlebitis | D010689 | 1 associated lipids |
| Pseudoxanthoma Elasticum | D011561 | 2 associated lipids |
| Eosinophilic Esophagitis | D057765 | 3 associated lipids |
| Common Bile Duct Diseases | D003137 | 3 associated lipids |
| Cestode Infections | D002590 | 3 associated lipids |
| Hyperbilirubinemia, Hereditary | D006933 | 3 associated lipids |
| Neointima | D058426 | 3 associated lipids |
| Mesenteric Vascular Occlusion | D008641 | 4 associated lipids |
| Eosinophilia | D004802 | 4 associated lipids |
| Insect Bites and Stings | D007299 | 4 associated lipids |
LTC4
Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.
Cross Reference
Introduction
To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with LTC4?
LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with LTC4
PubChem Associated disorders and diseases
What pathways are associated with LTC4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with LTC4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with LTC4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with LTC4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with LTC4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with LTC4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with LTC4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sabbah A et al. | [Allergy to mosquitoes and use of new immunobiological parameters]. | 1997 | Allerg Immunol (Paris) | pmid:9254117 |
| Sainte-Laudy J et al. | [Bioclinical interest in the assay of leukotrienes in four cases of sensitization to trophallergens]. | 1997 | Allerg Immunol (Paris) | pmid:9254120 |
| Akagi M et al. | Anti-allergic effect of tea-leaf saponin (TLS) from tea leaves (Camellia sinensis var. sinensis). | 1997 | Biol. Pharm. Bull. | pmid:9178940 |
| Stride BD et al. | Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells. | 1997 | Mol. Pharmacol. | pmid:9281595 |
| Patella V et al. | Heterogeneous effects of protamine on human mast cells and basophils. | 1997 | Br J Anaesth | pmid:9215027 |
| Hamasaki Y et al. | Post-transcriptional regulation of LTC4 synthase activity by retinoic acid in rat basophilic leukemia cells. | 1997 | Biochim. Biophys. Acta | pmid:9295165 |
| Jakobsson PJ et al. | Characterization of microsomal GST-II by western blot and identification of a novel LTC4 isomer. | 1997 | J Lipid Mediat Cell Signal | pmid:9302651 |
| Fujita M et al. | Cysteinyl leukotrienes induce nasal symptoms of allergic rhinitis via a receptor-mediated mechanism in guinea pigs. | 1997 | Jpn. J. Pharmacol. | pmid:9469641 |
| Schuligoi R et al. | Release of calcitonin gene-related peptide in cardiac anaphylaxis. | 1997 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:9050016 |
| Chavis C et al. | Leukotriene E4 plasma levels in adult asthmatic patients with variable disease severity. | 1997 | Allergy | pmid:9201374 |
| Gissurarson SR et al. | Effect of lobaric acid on cysteinyl-leukotriene formation and contractile activity of guinea pig taenia coli. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9023290 |
| Wijnholds J et al. | Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein. | 1997 | Nat. Med. | pmid:9359705 |
| Mullol J et al. | [Eosinophil activation by epithelial cells of the respiratory mucosa. Comparative study of normal mucosa and inflammatory mucosa]. | 1997 | Med Clin (Barc) | pmid:9303983 |
| Gomi A et al. | Transient induction of the MRP/GS-X pump and gamma-glutamylcysteine synthetase by 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3- nitrosourea in human glioma cells. | 1997 | Cancer Res. | pmid:9393752 |
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| Templeton AG et al. | Effects of S-salbutamol on human isolated bronchus. | 1998 | Pulm Pharmacol Ther | pmid:9802957 |
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| Kobayashi H et al. | Urinary trypsin inhibitor reduces the release of histamine from rat peritoneal mast cells. | 1998 | J. Lab. Clin. Med. | pmid:9579392 |
| Capra V et al. | Identification and characterization of two cysteinyl-leukotriene high affinity binding sites with receptor characteristics in human lung parenchyma. | 1998 | Mol. Pharmacol. | pmid:9547367 |
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