Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.
To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with LTC4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Taichman RS et al. | Human osteosarcomas inhibit hematopoietic colony formation: partial reversal by antibody to transforming growth factor-beta 1. | 1997 | Bone | pmid:9315339 |
Mullol J et al. | [Eosinophil activation by epithelial cells of the respiratory mucosa. Comparative study of normal mucosa and inflammatory mucosa]. | 1997 | Med Clin (Barc) | pmid:9303983 |
Jakobsson PJ et al. | Characterization of microsomal GST-II by western blot and identification of a novel LTC4 isomer. | 1997 | J Lipid Mediat Cell Signal | pmid:9302651 |
Hamasaki Y et al. | Post-transcriptional regulation of LTC4 synthase activity by retinoic acid in rat basophilic leukemia cells. | 1997 | Biochim. Biophys. Acta | pmid:9295165 |
Stride BD et al. | Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells. | 1997 | Mol. Pharmacol. | pmid:9281595 |
Cunningham FM et al. | Pharmacology of the 5-lipoxygenase inhibitors BAY Y 1015 and BAY X 1005 in the horse. | 1997 | J. Vet. Pharmacol. Ther. | pmid:9280370 |
Sainte-Laudy J et al. | [Bioclinical interest in the assay of leukotrienes in four cases of sensitization to trophallergens]. | 1997 | Allerg Immunol (Paris) | pmid:9254120 |
Sabbah A et al. | [Allergy to mosquitoes and use of new immunobiological parameters]. | 1997 | Allerg Immunol (Paris) | pmid:9254117 |
Ibe BO et al. | Leukotriene synthesis by isolated perinatal ovine intrapulmonary vessels correlates with age-related changes in 5-lipoxygenase protein. | 1997 | Biochem. Mol. Med. | pmid:9232199 |
Bacha EA et al. | Gastric antigen challenge releases gastrin and eicosanoids and protects against ethanol. | 1997 | J. Surg. Res. | pmid:9228931 |
Sabbah A et al. | [Anaphylactic or anaphylactoid reactions to paracetamol. Report of 3 cases]. | 1997 | Allerg Immunol (Paris) | pmid:9221011 |
Patella V et al. | Heterogeneous effects of protamine on human mast cells and basophils. | 1997 | Br J Anaesth | pmid:9215027 |
Chavis C et al. | Leukotriene E4 plasma levels in adult asthmatic patients with variable disease severity. | 1997 | Allergy | pmid:9201374 |
Forssmann U et al. | Eotaxin-2, a novel CC chemokine that is selective for the chemokine receptor CCR3, and acts like eotaxin on human eosinophil and basophil leukocytes. | 1997 | J. Exp. Med. | pmid:9182688 |
Leynadier F | [Drug allergies: value of the leucotriene C4 release test?]. | 1997 | Presse Med | pmid:9180883 |
Genovese A et al. | Loratadine and desethoxylcarbonyl-loratadine inhibit the immunological release of mediators from human Fc epsilon RI+ cells. | 1997 | Clin. Exp. Allergy | pmid:9179431 |
Akagi M et al. | Anti-allergic effect of tea-leaf saponin (TLS) from tea leaves (Camellia sinensis var. sinensis). | 1997 | Biol. Pharm. Bull. | pmid:9178940 |
Hamasaki Y et al. | The Chinese herbal medicine, shinpi-to, inhibits IgE-mediated leukotriene synthesis in rat basophilic leukemia-2H3 cells. | 1997 | J Ethnopharmacol | pmid:9174973 |
Planquois JM et al. | Differential inhibition by selective phosphodiesterase inhibitors of antigen, LTC4 and histamine-induced contraction of guinea-pig isolated trachea. | 1996 | Pulm Pharmacol | pmid:9160414 |
Abe T et al. | [Multidrug resistance protein (MRP)]. | 1997 | Nippon Rinsho | pmid:9155156 |