| MeSH term | MeSH ID | Detail |
|---|---|---|
| Airway Obstruction | D000402 | 13 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pulmonary Fibrosis | D011658 | 24 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
LTC4
Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.
Cross Reference
Introduction
To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with LTC4?
LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with LTC4
PubChem Associated disorders and diseases
What pathways are associated with LTC4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with LTC4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with LTC4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with LTC4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with LTC4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with LTC4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with LTC4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Marquardt DL et al. | Mast cell desensitization to IgE fails to induce a parallel adenosine receptor desensitization. | 1993 | Agents Actions | pmid:8147265 |
| Sirois MG et al. | Platelet activating factor modulates peptidoleukotriene effects on the permeability of bovine aortic endothelial cell to albumin. | 1993 | Agents Actions | pmid:8273559 |
| Rainsford KD | Leukotrienes in the pathogenesis of NSAID-induced gastric and intestinal mucosal damage. | 1993 | Agents Actions | pmid:8273575 |
| Butenko IG et al. | Anti-inflammatory properties and inhibition of leukotriene C4 biosynthesis in vitro by flavonoid baicalein from Scutellaria baicalensis georgy roots. | 1993 | Agents Actions | pmid:8273583 |
| Ramachers U et al. | Direct effects of second-generation H1-receptor antagonists on the activation of human basophils. | 1994 | Agents Actions | pmid:7526656 |
| Amon U et al. | Control function of protein kinase C isozymes on leukotriene generation from human basophils? | 1994 | Agents Actions | pmid:7976816 |
| Florio G et al. | The immunoglobulin superantigen-binding site of HIV-1 gp120 activates human basophils. | 2000 | AIDS | pmid:10853974 |
| Sabbah A et al. | [Allergy to mosquitoes and use of new immunobiological parameters]. | 1997 | Allerg Immunol (Paris) | pmid:9254117 |
| Sainte-Laudy J et al. | [Bioclinical interest in the assay of leukotrienes in four cases of sensitization to trophallergens]. | 1997 | Allerg Immunol (Paris) | pmid:9254120 |
| Sabbah A et al. | [Anaphylactic or anaphylactoid reactions to paracetamol. Report of 3 cases]. | 1997 | Allerg Immunol (Paris) | pmid:9221011 |
| Sabbah A et al. | [Testing basophil activation by flow cytometry in the diagnosis of allergy to hymenopteran venom]. | 1998 | Allerg Immunol (Paris) | pmid:9559061 |
| Sainte-Laudy J et al. | [Importance of the leukotriene C4 liberation test for the diagnosis of drug allergy (preliminary results)]. | 1996 | Allerg Immunol (Paris) | pmid:8703308 |
| Sainte-Laudy J et al. | [Demonstration of sulfite-group-specific IgE in patients with intolerance to preservatives]. | 1994 | Allerg Immunol (Paris) | pmid:7518236 |
| Collin N et al. | [Search for a threshold to distinguish between locoregional and systemic reactions using the histamine liberation value and the LTC4 level]. | 1999 | Allerg Immunol (Paris) | pmid:10070593 |
| Venière A et al. | [Importance of blood tests for the diagnosis of drug allergies]. | 2000 | Allerg Immunol (Paris) | pmid:10971854 |
| Karaman O et al. | The comparison of the efficacy of fluticasone propionate with cetirizine in perennial allergic rhinitis. | 2001 Mar-Apr | Allergol Immunopathol (Madr) | pmid:11420028 |
| Pereira-Vega A et al. | Premenstrual asthma and leukotriene variations in the menstrual cycle. | 2012 Nov-Dec | Allergol Immunopathol (Madr) | pmid:22115570 |
| Piette V et al. | Sinus CT scans and mediator release in nasal secretions after nasal challenge with cypress pollens. | 2004 | Allergy | pmid:15230820 |
| Zuberbier T et al. | Histamine releasability of basophils and skin mast cells in chronic urticaria. | 1996 | Allergy | pmid:8721524 |
| Gurzeler U et al. | In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8. | 2013 | Allergy | pmid:23590216 |