| MeSH term | MeSH ID | Detail |
|---|---|---|
| Endotoxemia | D019446 | 27 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
| Carotid Stenosis | D016893 | 15 associated lipids |
| Bronchial Hyperreactivity | D016535 | 15 associated lipids |
| Nasal Obstruction | D015508 | 4 associated lipids |
| Leukemia, Lymphocytic, Chronic, B-Cell | D015451 | 25 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Inflammatory Bowel Diseases | D015212 | 9 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Sneezing | D012912 | 6 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Rhinitis | D012220 | 10 associated lipids |
| Respiratory Hypersensitivity | D012130 | 18 associated lipids |
| Peptic Ulcer Hemorrhage | D010438 | 4 associated lipids |
| Respirovirus Infections | D010253 | 3 associated lipids |
| Otitis Media with Effusion | D010034 | 9 associated lipids |
| Neuralgia | D009437 | 28 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Influenza, Human | D007251 | 11 associated lipids |
LTD4
Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Asthma, Pneumonia and Allergic asthma. The involved functions are known as inhibitors, Signal Transduction, Cell Survival, antagonists and Phosphorylation. Ltd4 often locates in Membrane, Tissue membrane, Protoplasm, Cytoplasmic matrix and membrane fraction. The associated genes with LTD4 are ALOX5 gene, UMOD gene, P4HTM gene, RAF1 gene and Homologous Gene. The related lipids are Lipopolysaccharides.
Cross Reference
Introduction
To understand associated biological information of LTD4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with LTD4?
LTD4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Allergic asthma, Virus Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with LTD4
PubChem Associated disorders and diseases
What pathways are associated with LTD4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTD4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with LTD4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with LTD4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with LTD4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with LTD4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with LTD4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with LTD4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ishikawa J et al. | Involvement of endogenous tachykinins in LTD4-induced airway responses. | 1996 | Eur. Respir. J. | pmid:8730008 |
| Bäck M et al. | The cysteinyl-leukotriene receptor antagonist BAY u9773 is a competitive antagonist of leukotriene C4 in the guinea-pig ileum. | 1996 | Eur. J. Pharmacol. | pmid:8982726 |
| Burghardt JS et al. | Lipid mediators in oxygen-induced airway remodeling and hyperresponsiveness in newborn rats. | 1996 | Am. J. Respir. Crit. Care Med. | pmid:8887572 |
| Fukai F et al. | Transcellular biosynthesis of cysteinyl leukotrienes by Kupffer cell-hepatocyte cooperation in rat liver. | 1996 | Cell Biol. Int. | pmid:8858827 |
| Abraham WM et al. | Effect of TYB-2285 on antigen-induced airway responses in sheep. | 1996 | Pulm Pharmacol | pmid:8843510 |
| Wensing G et al. | Pharmacodynamics and pharmacokinetics of BAY x 7195 aerosol, a new and selective receptor antagonist of cysteinyl-leukotrienes, in normal volunteers. | 1996 | Br J Clin Pharmacol | pmid:8864314 |
| Tai S et al. | Effect of leukotriene D4 on tracheal mucociliary transport velocity in quails. | 1996 | Jpn. J. Pharmacol. | pmid:8866758 |
| Martin CA et al. | In vitro pharmacological effects of S 12370 (2-[4-benzhydryloxypiperidinoethyl]isoxindole; an antibronchoconstrictor agent) in normal and sensitized tissue. | 1996 | Fundam Clin Pharmacol | pmid:8902549 |
| Omori C et al. | Eicosanoids modulate hyperpnea-induced bronchoconstriction in canine peripheral airways. | 1996 | J. Appl. Physiol. | pmid:8889761 |
| Chong K et al. | Drug substance manufacture process control: application of flow injection analysis and HPLC for monitoring an enantiospecific synthesis. | 1996 | J Pharm Biomed Anal | pmid:8895082 |
| Nakamura S et al. | Effects of 1-[3-(4-benzhydryl-1-piperazinyl)propyl]-3- (1H-imidazol-1-ylmethyl)-1H-indole-6-carboxylic acid with thromboxane A2 synthetase inhibitory and H1-blocking activities on anaphylactic bronchospasm. | 1996 | Arzneimittelforschung | pmid:8955866 |
| Garcia C et al. | Effects of synthetic peptido-leukotrienes on bone resorption in vitro. | 1996 | J. Bone Miner. Res. | pmid:8992883 |
| Hazel BA et al. | Induction of granulocytic differentiation in a mouse model by benzene and hydroquinone. | 1996 | Environ. Health Perspect. | pmid:9118902 |
| Tominaga M et al. | ONO-1078 antagonizes diarrhea-causing changes in ion transport and smooth muscle contraction induced by peptidoleukotrienes in rat and human colon in vitro. | 1996 | J. Pharmacol. Exp. Ther. | pmid:8819486 |
| Joki S et al. | Effect of leukotriene D4 on ciliary activity in human, guinea-pig and rat respiratory mucosa. | 1996 | Pulm Pharmacol | pmid:9160411 |
| Papayianni A et al. | Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells. | 1996 | J. Immunol. | pmid:8690917 |
| Kang BC et al. | Experimental asthma developed by room air contamination with cockroach allergen. | 1996 | Int. Arch. Allergy Immunol. | pmid:8917126 |
| Ganbo T et al. | Leukotriene C4 inhibits ciliary activity in the presence of gamma-glutamyl transpeptidase. | 1996 | Am. J. Physiol. | pmid:8770059 |
| Funayama T et al. | Role of Leukotriene-degrading enzymes in pulmonary response to antigen infusion in sensitized guinea pigs in vivo. | 1996 | Am. J. Respir. Cell Mol. Biol. | pmid:8703483 |
| Grönroos E et al. | Leukotriene D4-induced mobilization of intracellular Ca2+ in epithelial cells is critically dependent on activation of the small GTP-binding protein Rho. | 1996 | Biochem. J. | pmid:8645211 |