Wulff T et al. |
Co-expression of mCysLT1 receptors and IK channels in Xenopus laevis oocytes elicits LTD4-stimulated IK current, independent of an increase in [Ca2+]i. |
2004 |
Biochim. Biophys. Acta |
pmid:14757222
|
Mezhybovska M et al. |
Pro-inflammatory mediator leukotriene D4 induces transcriptional activity of potentially oncogenic genes. |
2005 |
Biochem. Soc. Trans. |
pmid:16042577
|
Ravasi S et al. |
Pharmacological differences among CysLT(1) receptor antagonists with respect to LTC(4) and LTD(4) in human lung parenchyma. |
2002 |
Biochem. Pharmacol. |
pmid:11996896
|
Martin V et al. |
Molecular cloning and functional characterization of murine cysteinyl-leukotriene 1 (CysLT(1)) receptors. |
2001 |
Biochem. Pharmacol. |
pmid:11705452
|
Capra V et al. |
CysLT1 signal transduction in differentiated U937 cells involves the activation of the small GTP-binding protein Ras. |
2004 |
Biochem. Pharmacol. |
pmid:15041474
|
Nieves D and Moreno JJ |
Role of 5-lipoxygenase pathway in the regulation of RAW 264.7 macrophage proliferation. |
2006 |
Biochem. Pharmacol. |
pmid:16934759
|
Wikström K et al. |
The anti-apoptotic effect of leukotriene D4 involves the prevention of caspase 8 activation and Bid cleavage. |
2003 |
Biochem. J. |
pmid:12482325
|
Grönroos E et al. |
Leukotriene D4-induced mobilization of intracellular Ca2+ in epithelial cells is critically dependent on activation of the small GTP-binding protein Rho. |
1996 |
Biochem. J. |
pmid:8645211
|
Thodeti CK et al. |
Leukotriene D4 induces association of active RhoA with phospholipase C-gamma1 in intestinal epithelial cells. |
2002 |
Biochem. J. |
pmid:12071848
|
Hirata F et al. |
IL-1 beta regulates the expression of the Gi2 alpha gene via lipid mediators in guinea pig tracheal muscle. |
1994 |
Biochem. Biophys. Res. Commun. |
pmid:7945342
|
Adolfsson JL et al. |
Leukotriene D4-induced activation and translocation of the G-protein alpha i3-subunit in human epithelial cells. |
1996 |
Biochem. Biophys. Res. Commun. |
pmid:8806649
|
Wang ML et al. |
Leukotriene D4 induces brain edema and enhances CysLT2 receptor-mediated aquaporin 4 expression. |
2006 |
Biochem. Biophys. Res. Commun. |
pmid:17010308
|
Tada N et al. |
Experimental otitis media with effusion induced by leukotriene D4. |
2002 |
Auris Nasus Larynx |
pmid:11893446
|
Chiba Y et al. |
Regional differences in vascular responsiveness of nasal mucosae isolated from naive guinea pigs. |
2007 |
Auris Nasus Larynx |
pmid:17056219
|
Bai CH et al. |
The inhibitory effect of the leukotriene receptor antagonist on leukotriene D4-induced MUC2/5AC gene expression and mucin secretion in human airway epithelial cells. |
2007 |
Auris Nasus Larynx |
pmid:17223000
|
Porreca E et al. |
Modulation of rat vascular smooth muscle cell (VSMC) proliferation by cysteinyl leukotriene D4: a role for mediation of interleukin 1. |
1995 |
Atherosclerosis |
pmid:7755646
|
Porreca E et al. |
Cysteinyl-leukotriene D4 induced IL-1 beta expression and release in rat vascular smooth muscle cells. |
1995 |
Atherosclerosis |
pmid:7661877
|
Kumasawa F et al. |
Mitogen-activated protein kinase (MAPK) regulates leukotriene D4-induced HB-EGF and ADAM12 expression in human airway smooth muscle cells. |
2013 |
Asian Pac. J. Allergy Immunol. |
pmid:23517395
|
Ganbo T et al. |
Effect of ibudilast on ciliary activity of human paranasal sinus mucosa in vitro. |
1995 |
Arzneimittelforschung |
pmid:7575753
|
Nakamura S et al. |
Effects of 1-[3-(4-benzhydryl-1-piperazinyl)propyl]-3- (1H-imidazol-1-ylmethyl)-1H-indole-6-carboxylic acid with thromboxane A2 synthetase inhibitory and H1-blocking activities on anaphylactic bronchospasm. |
1996 |
Arzneimittelforschung |
pmid:8955866
|
Tasaka K et al. |
Effect of loratadine on immediate and delayed type hypersensitivity reactions. |
1995 |
Arzneimittelforschung |
pmid:8573225
|
Fauler J et al. |
Enhanced synthesis of cysteinyl leukotrienes in juvenile rheumatoid arthritis. |
1994 |
Arthritis Rheum. |
pmid:8129769
|
Kawagishi Y et al. |
[Clinical significance of measurement of urinary leukotriene E4 in asthmatic patients without attack]. |
2001 |
Arerugi |
pmid:11761885
|
Marcelle R |
Leukotrienes antagonist-inhibitor and the bronchial response to inhaled antigen in actively sensitized guinea-pigs. |
1998 |
Arch. Physiol. Biochem. |
pmid:9711356
|
Abe M et al. |
A novel method for preserving human lungs using a super-cooling system. |
2006 |
Ann. Thorac. Surg. |
pmid:16928543
|
Hoopes C |
Invited commentary. |
2006 |
Ann. Thorac. Surg. |
pmid:16928544
|
Konno A et al. |
Role of substance P in the vascular response of nasal mucosa in nasal allergy. |
1996 |
Ann. Otol. Rhinol. Laryngol. |
pmid:8712637
|
Ganbo T et al. |
Inhibition of mucociliary clearance of the eustachian tube by leukotrienes C4 and D4. |
1995 |
Ann. Otol. Rhinol. Laryngol. |
pmid:7872607
|
Mayatepek E et al. |
A patient with neurological symptoms and abnormal leukotriene metabolism: a new defect in leukotriene biosynthesis. |
2005 |
Ann. Neurol. |
pmid:16315285
|
Sjölander A and Grönroos E |
Leukotriene D4-induced signal transduction. |
1994 |
Ann. N. Y. Acad. Sci. |
pmid:7825836
|
Krell RD et al. |
Preclinical exploration of the potential antiinflammatory properties of the peptide leukotriene antagonist ICI 204,219 (Accolate). |
1994 |
Ann. N. Y. Acad. Sci. |
pmid:7825851
|
Möhle R et al. |
Transendothelial migration of hematopoietic progenitor cells. Role of chemotactic factors. |
2001 |
Ann. N. Y. Acad. Sci. |
pmid:11458515
|
Kim SH et al. |
Regulation of monocyte chemoattractant protein 1 by cysteinyl leukotriene D4 in human lung epithelial A549 cells. |
2009 |
Ann. Allergy Asthma Immunol. |
pmid:19852204
|
Smith LJ et al. |
A single dose of zafirlukast reduces LTD4-induced bronchoconstriction in patients on maintenance inhaled corticosteroid therapy. |
1998 |
Ann. Allergy Asthma Immunol. |
pmid:9690572
|
Shirasaki H et al. |
Agonist- and T(H)2 cytokine-induced up-regulation of cysteinyl leukotriene receptor messenger RNA in human monocytes. |
2007 |
Ann. Allergy Asthma Immunol. |
pmid:17941281
|
Saito K et al. |
Leukotriene D4 and eosinophil transendothelial migration, superoxide generation, and degranulation via beta2 integrin. |
2004 |
Ann. Allergy Asthma Immunol. |
pmid:15609771
|
Simons FE et al. |
Suppression of the early and late cutaneous allergic responses using fexofenadine and montelukast. |
2001 |
Ann. Allergy Asthma Immunol. |
pmid:11206237
|
Hendeles L and Marshik PL |
Zileuton: a new therapy for asthma or just the first of a new class of drugs. |
1996 Jul-Aug |
Ann Pharmacother |
pmid:8826576
|
Welch MJ et al. |
Effect of RG 12525, a new leukotriene antagonist, on pulmonary function of asthmatic adults. |
1994 |
Ann Allergy |
pmid:8154635
|
White IJ et al. |
A continuous fluorometric assay for leukotriene D4 hydrolase. |
1999 |
Anal. Biochem. |
pmid:10075814
|
Manning PJ et al. |
Exercise-induced refractoriness in asthmatic subjects involves leukotriene and prostaglandin interdependent mechanisms. |
1993 |
Am. Rev. Respir. Dis. |
pmid:8214949
|
Venugopal CS et al. |
Comparative responses of bronchial rings to mediators of airway hyperreactivity in healthy horses and those affected with summer pasture-associated obstructive pulmonary disease. |
2001 |
Am. J. Vet. Res. |
pmid:11212036
|
Lavoie JP et al. |
Comparison of effects of dexamethasone and the leukotriene D4 receptor antagonist L-708,738 on lung function and airway cytologic findings in horses with recurrent airway obstruction. |
2002 |
Am. J. Vet. Res. |
pmid:11939323
|
Suzuki R and Freed AN |
Heparin inhibits hyperventilation-induced late-phase hyperreactivity in dogs. |
2002 |
Am. J. Respir. Crit. Care Med. |
pmid:11779726
|
Ichinose M et al. |
Antigen-induced airway responses are inhibited by a potassium channel opener. |
1994 |
Am. J. Respir. Crit. Care Med. |
pmid:7519521
|
Nagase T et al. |
In vitro airway and tissue response to antigen in sensitized rats. Role of serotonin and leukotriene D4. |
1995 |
Am. J. Respir. Crit. Care Med. |
pmid:7599867
|
Macfarlane AJ et al. |
Sputum cysteinyl leukotrienes increase 24 hours after allergen inhalation in atopic asthmatics. |
2000 |
Am. J. Respir. Crit. Care Med. |
pmid:10806153
|
Burghardt JS et al. |
Lipid mediators in oxygen-induced airway remodeling and hyperresponsiveness in newborn rats. |
1996 |
Am. J. Respir. Crit. Care Med. |
pmid:8887572
|
Underwood DC et al. |
Persistent airway eosinophilia after leukotriene (LT) D4 administration in the guinea pig: modulation by the LTD4 receptor antagonist, pranlukast, or an interleukin-5 monoclonal antibody. |
1996 |
Am. J. Respir. Crit. Care Med. |
pmid:8887574
|
Fukuyama S et al. |
Effect of eotaxin and platelet-activating factor on airway inflammation and hyperresponsiveness in guinea pigs in vivo. |
2000 |
Am. J. Respir. Crit. Care Med. |
pmid:10852755
|
Diamant Z et al. |
The effect of inhaled leukotriene D4 and methacholine on sputum cell differentials in asthma. |
1997 |
Am. J. Respir. Crit. Care Med. |
pmid:9105062
|
Sloniewsky DE et al. |
Leukotriene D4 activates alveolar epithelial Na,K-ATPase and increases alveolar fluid clearance. |
2004 |
Am. J. Respir. Crit. Care Med. |
pmid:14578215
|
Nagase T et al. |
Roles of calcitonin gene-related peptide (CGRP) in hyperpnea-induced constriction in guinea pigs. |
1996 |
Am. J. Respir. Crit. Care Med. |
pmid:8912779
|
Dahlén B et al. |
Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics. |
1998 |
Am. J. Respir. Crit. Care Med. |
pmid:9563738
|
Donnelly AL et al. |
The leukotriene D4-receptor antagonist, ICI 204,219, relieves symptoms of acute seasonal allergic rhinitis. |
1995 |
Am. J. Respir. Crit. Care Med. |
pmid:7767514
|
Mulder A et al. |
Effect of inhaled leukotriene D4 on airway eosinophilia and airway hyperresponsiveness in asthmatic subjects. |
1999 |
Am. J. Respir. Crit. Care Med. |
pmid:10228127
|
Gauvreau GM et al. |
Inhaled leukotriene E(4), but not leukotriene D(4), increased airway inflammatory cells in subjects with atopic asthma. |
2001 |
Am. J. Respir. Crit. Care Med. |
pmid:11704602
|
Dandurand RJ et al. |
In vitro allergic bronchoconstriction in the brown Norway rat. |
1994 |
Am. J. Respir. Crit. Care Med. |
pmid:8004305
|
Muñoz NM et al. |
Eosinophil chemotaxis inhibited by 5-lipoxygenase blockade and leukotriene receptor antagonism. |
1997 |
Am. J. Respir. Crit. Care Med. |
pmid:9105085
|
Ellis JL and Undem BJ |
Role of cysteinyl-leukotrienes and histamine in mediating intrinsic tone in isolated human bronchi. |
1994 |
Am. J. Respir. Crit. Care Med. |
pmid:8111568
|
Echazarreta AL et al. |
Pulmonary gas exchange and sputum cellular responses to inhaled leukotriene D(4) in asthma. |
2001 |
Am. J. Respir. Crit. Care Med. |
pmid:11463588
|
Hasday JD et al. |
Anti-inflammatory effects of zileuton in a subpopulation of allergic asthmatics. |
2000 |
Am. J. Respir. Crit. Care Med. |
pmid:10764316
|
Powell WS et al. |
Effects of dexamethasone on leukotriene synthesis and airway responses to antigen and leukotriene D4 in rats. |
1995 |
Am. J. Respir. Crit. Care Med. |
pmid:7697244
|
Accomazzo MR et al. |
Leukotriene D4-induced activation of smooth-muscle cells from human bronchi is partly Ca2+-independent. |
2001 |
Am. J. Respir. Crit. Care Med. |
pmid:11208655
|
Aharony D |
Pharmacology of leukotriene receptor antagonists |
1998 |
Am. J. Respir. Crit. Care Med. |
pmid:9620942
|
Allakhverdi Z et al. |
Inhibition of antigen-induced eosinophilia and airway hyperresponsiveness by antisense oligonucleotides directed against the common beta chain of IL-3, IL-5, GM-CSF receptors in a rat model of allergic asthma. |
2002 |
Am. J. Respir. Crit. Care Med. |
pmid:11934731
|
Nag S et al. |
Interleukin-2-induced increased airway responsiveness and lung Th2 cytokine expression occur after antigen challenge through the leukotriene pathway. |
2002 |
Am. J. Respir. Crit. Care Med. |
pmid:12045130
|
Vargaftig BB and Singer M |
Leukotrienes mediate murine bronchopulmonary hyperreactivity, inflammation, and part of mucosal metaplasia and tissue injury induced by recombinant murine interleukin-13. |
2003 |
Am. J. Respir. Cell Mol. Biol. |
pmid:12654629
|
Potter-Perigo S et al. |
Regulation of proteoglycan synthesis by leukotriene d4 and epidermal growth factor in bronchial smooth muscle cells. |
2004 |
Am. J. Respir. Cell Mol. Biol. |
pmid:12855404
|
Undem BJ et al. |
Recombinant stem cell factor-induced mast cell activation and smooth muscle contraction in human bronchi. |
1994 |
Am. J. Respir. Cell Mol. Biol. |
pmid:7524570
|
Ménard G and Bissonnette EY |
Priming of alveolar macrophages by leukotriene D(4): potentiation of inflammation. |
2000 |
Am. J. Respir. Cell Mol. Biol. |
pmid:11017925
|
Panettieri RA et al. |
Effects of LTD4 on human airway smooth muscle cell proliferation, matrix expression, and contraction In vitro: differential sensitivity to cysteinyl leukotriene receptor antagonists. |
1998 |
Am. J. Respir. Cell Mol. Biol. |
pmid:9730873
|
Thompson C et al. |
Leukotriene D4 up-regulates furin expression through CysLT1 receptor signaling. |
2008 |
Am. J. Respir. Cell Mol. Biol. |
pmid:18323532
|
Funayama T et al. |
Role of Leukotriene-degrading enzymes in pulmonary response to antigen infusion in sensitized guinea pigs in vivo. |
1996 |
Am. J. Respir. Cell Mol. Biol. |
pmid:8703483
|
Thompson C et al. |
CysLT1 receptor engagement induces activator protein-1- and NF-kappaB-dependent IL-8 expression. |
2006 |
Am. J. Respir. Cell Mol. Biol. |
pmid:16809637
|
Pugliese AM et al. |
Functional characterization of two isoforms of the P2Y-like receptor GPR17: [35S]GTPgammaS binding and electrophysiological studies in 1321N1 cells. |
2009 |
Am. J. Physiol., Cell Physiol. |
pmid:19625605
|
Arthur S and Sundaram U |
Protein kinase C-mediated phosphorylation of RKIP regulates inhibition of Na-alanine cotransport by leukotriene D(4) in intestinal epithelial cells. |
2014 |
Am. J. Physiol., Cell Physiol. |
pmid:25231108
|
Minobe E et al. |
A new phosphorylation site in cardiac L-type Ca2+ channels (Cav1.2) responsible for its cAMP-mediated modulation. |
2014 |
Am. J. Physiol., Cell Physiol. |
pmid:25209265
|
Vargaftig BB and Singer M |
Leukotrienes mediate part of Ova-induced lung effects in mice via EGFR. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12794006
|
Carbajal V et al. |
LTD4 induces hyperresponsiveness to histamine in bovine airway smooth muscle: role of SR-ATPase Ca2+ pump and tyrosine kinase. |
2005 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:15377496
|
Yang G et al. |
Transgenic smooth muscle expression of the human CysLT1 receptor induces enhanced responsiveness of murine airways to leukotriene D4. |
2004 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:15064240
|
McGovern T et al. |
LTDâ‚„ induces HB-EGF-dependent CXCL8 release through EGFR activation in human bronchial epithelial cells. |
2010 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:20889674
|
Oliveira SH et al. |
SCF-induced airway hyperreactivity is dependent on leukotriene production. |
2001 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:11350804
|
Nagase T et al. |
A potent inhibitor of cytosolic phospholipase A2, arachidonyl trifluoromethyl ketone, attenuates LPS-induced lung injury in mice. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12505870
|
Liu P et al. |
Cysteinyl leukotriene-dependent [Ca2+]i responses to angiotensin II in cardiomyocytes. |
2003 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:12531730
|
Talukder JR et al. |
Mechanism of leukotriene D4 inhibition of Na-alanine cotransport in intestinal epithelial cells. |
2008 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:18436626
|
Cohen P et al. |
Leukotriene D4 facilitates airway smooth muscle cell proliferation via modulation of the IGF axis. |
1995 |
Am. J. Physiol. |
pmid:7544535
|
Goldhill J et al. |
Interleukin-4 modulates cholinergic neural control of mouse small intestinal longitudinal muscle. |
1997 |
Am. J. Physiol. |
pmid:9176223
|
Rajah R et al. |
Leukotriene D4 induces MMP-1, which functions as an IGFBP protease in human airway smooth muscle cells. |
1996 |
Am. J. Physiol. |
pmid:8997273
|
Olszewski MA et al. |
Mediators of anaphylaxis but not activated neutrophils augment cholinergic responses of equine small airways. |
1999 |
Am. J. Physiol. |
pmid:10070118
|
Olszewski MA et al. |
Pre- and postjunctional effects of inflammatory mediators in horse airways. |
1999 |
Am. J. Physiol. |
pmid:10444527
|
Hyun CS and Binder HJ |
Mechanism of leukotriene D4 stimulation of Cl- secretion in rat distal colon in vitro. |
1993 |
Am. J. Physiol. |
pmid:8214069
|
Pawloski JR and Chapnick BM |
Antagonism of LTD4-evoked relaxation in canine renal artery and vein. |
1993 |
Am. J. Physiol. |
pmid:8214135
|
Fiorucci S et al. |
Effect of NSAIDs on pepsinogen secretion and calcium mobilization in isolated chief cells. |
1995 |
Am. J. Physiol. |
pmid:7611418
|
Sato E et al. |
Acetylcholine stimulates alveolar macrophages to release inflammatory cell chemotactic activity. |
1998 |
Am. J. Physiol. |
pmid:9609736
|
Han H et al. |
Effects of LTD4 and its specific antagonist L-660,711 in isolated rat hearts with chronic myocardial infarction. |
1994 |
Am. J. Physiol. |
pmid:8203604
|
Abela A and Daniel EE |
Neural and myogenic effects of leukotrienes C4, D4, and E4 on canine bronchial smooth muscle. |
1994 |
Am. J. Physiol. |
pmid:8179018
|
Ganbo T et al. |
Leukotriene C4 inhibits ciliary activity in the presence of gamma-glutamyl transpeptidase. |
1996 |
Am. J. Physiol. |
pmid:8770059
|
Han B et al. |
Gamma-glutamyl leukotrienase, a novel endothelial membrane protein, is specifically responsible for leukotriene D(4) formation in vivo. |
2002 |
Am. J. Pathol. |
pmid:12163373
|
Gronert K et al. |
Selectivity of recombinant human leukotriene D(4), leukotriene B(4), and lipoxin A(4) receptors with aspirin-triggered 15-epi-LXA(4) and regulation of vascular and inflammatory responses. |
2001 |
Am. J. Pathol. |
pmid:11141472
|