| MeSH term | MeSH ID | Detail |
|---|---|---|
| Rhinitis | D012220 | 10 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Glomerulonephritis | D005921 | 35 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Hypersensitivity, Immediate | D006969 | 14 associated lipids |
LTD4
Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Asthma, Pneumonia and Allergic asthma. The involved functions are known as inhibitors, Signal Transduction, Cell Survival, antagonists and Phosphorylation. Ltd4 often locates in Membrane, Tissue membrane, Protoplasm, Cytoplasmic matrix and membrane fraction. The associated genes with LTD4 are ALOX5 gene, UMOD gene, P4HTM gene, RAF1 gene and Homologous Gene. The related lipids are Lipopolysaccharides.
Cross Reference
Introduction
To understand associated biological information of LTD4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with LTD4?
LTD4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Allergic asthma, Virus Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with LTD4
PubChem Associated disorders and diseases
What pathways are associated with LTD4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTD4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with LTD4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with LTD4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with LTD4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with LTD4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with LTD4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with LTD4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Guan W et al. | Leukotriene D4 and methacholine bronchial provocation tests for identifying leukotriene-responsiveness subtypes. | 2013 | J. Allergy Clin. Immunol. | pmid:23040886 |
| RodrÃguez-Lagunas MJ et al. | 5-Hydroxyeicosatetraenoic acid and leukotriene D4 increase intestinal epithelial paracellular permeability. | 2013 | Int. J. Biochem. Cell Biol. | pmid:23583294 |
| Kumasawa F et al. | Mitogen-activated protein kinase (MAPK) regulates leukotriene D4-induced HB-EGF and ADAM12 expression in human airway smooth muscle cells. | 2013 | Asian Pac. J. Allergy Immunol. | pmid:23517395 |
| Ahmed T et al. | Inhibition of allergic airway responses by heparin derived oligosaccharides: identification of a tetrasaccharide sequence. | 2012 | Respir. Res. | pmid:22269021 |
| Provost V et al. | Leukotriene D4 and interleukin-13 cooperate to increase the release of eotaxin-3 by airway epithelial cells. | 2012 | PLoS ONE | pmid:22952702 |
| Dahlén B et al. | Salbutamol but not ipratropium abolishes leukotriene D4-induced gas exchange abnormalities in asthma. | 2012 | Eur. J. Clin. Pharmacol. | pmid:22457014 |
| Huang XQ et al. | Transforming growth factor β1-induced astrocyte migration is mediated in part by activating 5-lipoxygenase and cysteinyl leukotriene receptor 1. | 2012 | J Neuroinflammation | pmid:22734808 |
| Dannull J et al. | Leukotriene C4 induces migration of human monocyte-derived dendritic cells without loss of immunostimulatory function. | 2012 | Blood | pmid:22323449 |
| Pelclová D et al. | Leukotrienes B4, C4, D4 and E4 in the exhaled breath condensate (EBC), blood and urine in patients with pneumoconiosis. | 2012 | Ind Health | pmid:22785421 |
| Drost AC et al. | The G protein-coupled receptor CysLT1 mediates chemokine-like effects and prolongs survival in chronic lymphocytic leukemia. | 2012 | Leuk. Lymphoma | pmid:21936770 |