| MeSH term | MeSH ID | Detail |
|---|---|---|
| Respiratory Hypersensitivity | D012130 | 18 associated lipids |
| Leukemia, Lymphocytic, Chronic, B-Cell | D015451 | 25 associated lipids |
| Otitis Media with Effusion | D010034 | 9 associated lipids |
| Coronary Artery Disease | D003324 | 47 associated lipids |
| Cough | D003371 | 19 associated lipids |
| Enteritis | D004751 | 8 associated lipids |
| Bronchial Hyperreactivity | D016535 | 15 associated lipids |
| Carotid Stenosis | D016893 | 15 associated lipids |
| Influenza, Human | D007251 | 11 associated lipids |
| Asthma, Exercise-Induced | D001250 | 10 associated lipids |
LTD4
Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Asthma, Pneumonia and Allergic asthma. The involved functions are known as inhibitors, Signal Transduction, Cell Survival, antagonists and Phosphorylation. Ltd4 often locates in Membrane, Tissue membrane, Protoplasm, Cytoplasmic matrix and membrane fraction. The associated genes with LTD4 are ALOX5 gene, UMOD gene, P4HTM gene, RAF1 gene and Homologous Gene. The related lipids are Lipopolysaccharides.
Cross Reference
Introduction
To understand associated biological information of LTD4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with LTD4?
LTD4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Allergic asthma, Virus Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with LTD4
PubChem Associated disorders and diseases
What pathways are associated with LTD4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTD4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with LTD4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with LTD4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with LTD4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with LTD4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with LTD4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with LTD4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Spada CS et al. | Comparison of leukotriene B4 and D4 effects on human eosinophil and neutrophil motility in vitro. | 1994 | J. Leukoc. Biol. | pmid:8301215 |
| Krauss AH et al. | Determination of leukotriene effects on human neutrophil chemotaxis in vitro by differential assessment of cell motility and polarity. | 1994 | J. Leukoc. Biol. | pmid:8301217 |
| Ibe BO et al. | Plasma and urinary leukotrienes in sickle cell disease: possible role in the inflammatory process. | 1994 | Eur. J. Clin. Invest. | pmid:8187808 |
| Kargman S et al. | Protein kinase C-dependent regulation of sulfidopeptide leukotriene biosynthesis and leukotriene C4 synthase in neutrophilic HL-60 cells. | 1994 | Mol. Pharmacol. | pmid:8190095 |
| Petric R and Ford-Hutchinson AW | Elevated cysteinyl leukotriene excretion in experimental glomerulonephritis. | 1994 | Kidney Int. | pmid:7853790 |
| Leier I et al. | The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates. | 1994 | J. Biol. Chem. | pmid:7961706 |
| An S et al. | Molecular cloning of sheep lung dipeptidase: a glycosyl phosphatidylinositol-anchored ectoenzyme that converts leukotriene D4 to leukotriene E4. | 1994 | Biochim. Biophys. Acta | pmid:8054366 |
| Tsopanoglou NE et al. | Leukotrienes C4 and D4 promote angiogenesis via a receptor-mediated interaction. | 1994 | Eur. J. Pharmacol. | pmid:7523148 |
| Kelley M et al. | Induction of peroxisomal enzymes by a tetrazole-substituted 2-quinolinylmethoxy leukotriene D4 antagonist. | 1994 | Fundam Appl Toxicol | pmid:7982537 |
| Ellis JL and Undem BJ | Role of cysteinyl-leukotrienes and histamine in mediating intrinsic tone in isolated human bronchi. | 1994 | Am. J. Respir. Crit. Care Med. | pmid:8111568 |
| Welch MJ et al. | Effect of RG 12525, a new leukotriene antagonist, on pulmonary function of asthmatic adults. | 1994 | Ann Allergy | pmid:8154635 |
| Dahlén B et al. | The leukotriene-antagonist ICI-204,219 inhibits the early airway reaction to cumulative bronchial challenge with allergen in atopic asthmatics. | 1994 | Eur. Respir. J. | pmid:8162986 |
| Han H et al. | Effects of LTD4 and its specific antagonist L-660,711 in isolated rat hearts with chronic myocardial infarction. | 1994 | Am. J. Physiol. | pmid:8203604 |
| Abela A and Daniel EE | Neural and myogenic effects of leukotrienes C4, D4, and E4 on canine bronchial smooth muscle. | 1994 | Am. J. Physiol. | pmid:8179018 |
| Kurosawa M et al. | Inhibition by a novel peptide leukotriene receptor antagonist ONO-1078 of airway wall thickening and airway hyperresponsiveness to histamine induced by leukotriene C4 or leukotriene D4 in guinea-pigs. | 1994 | Clin. Exp. Allergy | pmid:7842366 |
| Oliva D et al. | Correlation between leukotriene D4-induced contraction and cytosolic calcium elevation: a quantitative and simultaneous evaluation in smooth muscle. | 1994 | J. Pharmacol. Exp. Ther. | pmid:8301553 |
| Herd CM et al. | Effect of a 5-lipoxygenase inhibitor and leukotriene antagonist (PF 5901) on antigen-induced airway responses in neonatally immunized rabbits. | 1994 | Br. J. Pharmacol. | pmid:8032653 |
| Thioudellet C et al. | Molecular and functional characterization of recombinant human gamma-glutamyltransferase. Coupling of its activity to glutathione levels in V79 cells. | 1994 | Eur. J. Biochem. | pmid:7913033 |
| Mion F et al. | Short term effects of indomethacin on rat small intestinal permeability. Role of eicosanoids and platelet activating factor. | 1994 | Gut | pmid:8174986 |
| Salari H et al. | Involvement of immunologic mechanisms in a guinea pig model of western red cedar asthma. | 1994 | J. Allergy Clin. Immunol. | pmid:8182231 |