LTD4

Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Asthma, Pneumonia and Allergic asthma. The involved functions are known as inhibitors, Signal Transduction, Cell Survival, antagonists and Phosphorylation. Ltd4 often locates in Membrane, Tissue membrane, Protoplasm, Cytoplasmic matrix and membrane fraction. The associated genes with LTD4 are ALOX5 gene, UMOD gene, P4HTM gene, RAF1 gene and Homologous Gene. The related lipids are Lipopolysaccharides.

Cross Reference

Introduction

To understand associated biological information of LTD4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with LTD4?

LTD4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Allergic asthma, Virus Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with LTD4

MeSH term MeSH ID Detail
Endotoxemia D019446 27 associated lipids
Respirovirus Infections D010253 3 associated lipids
Neuralgia D009437 28 associated lipids
Sneezing D012912 6 associated lipids
Peptic Ulcer Hemorrhage D010438 4 associated lipids
Nasal Obstruction D015508 4 associated lipids
Respiratory Syncytial Virus Infections D018357 10 associated lipids
Asbestosis D001195 8 associated lipids
Aspergillosis, Allergic Bronchopulmonary D001229 2 associated lipids
Per page 10 20 50 | Total 39

PubChem Associated disorders and diseases

What pathways are associated with LTD4

Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTD4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with LTD4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with LTD4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with LTD4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with LTD4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with LTD4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with LTD4

Download all related citations
Per page 10 20 50 100 | Total 640
Authors Title Published Journal PubMed Link
Hisamatsu K et al. Effect of leukotriene C4 exposure on ciliated cells of the nasal mucosa. 1996 Prostaglandins pmid:8900445
Chong K et al. Drug substance manufacture process control: application of flow injection analysis and HPLC for monitoring an enantiospecific synthesis. 1996 J Pharm Biomed Anal pmid:8895082
Omori C et al. Eicosanoids modulate hyperpnea-induced bronchoconstriction in canine peripheral airways. 1996 J. Appl. Physiol. pmid:8889761
Underwood DC et al. Persistent airway eosinophilia after leukotriene (LT) D4 administration in the guinea pig: modulation by the LTD4 receptor antagonist, pranlukast, or an interleukin-5 monoclonal antibody. 1996 Am. J. Respir. Crit. Care Med. pmid:8887574
Burghardt JS et al. Lipid mediators in oxygen-induced airway remodeling and hyperresponsiveness in newborn rats. 1996 Am. J. Respir. Crit. Care Med. pmid:8887572
Tai S et al. Effect of leukotriene D4 on tracheal mucociliary transport velocity in quails. 1996 Jpn. J. Pharmacol. pmid:8866758
Wensing G et al. Pharmacodynamics and pharmacokinetics of BAY x 7195 aerosol, a new and selective receptor antagonist of cysteinyl-leukotrienes, in normal volunteers. 1996 Br J Clin Pharmacol pmid:8864314
Fukai F et al. Transcellular biosynthesis of cysteinyl leukotrienes by Kupffer cell-hepatocyte cooperation in rat liver. 1996 Cell Biol. Int. pmid:8858827
Abraham WM et al. Effect of TYB-2285 on antigen-induced airway responses in sheep. 1996 Pulm Pharmacol pmid:8843510
Ochsner M The action of the peptidoleukotriene LTD4 on intracellular calcium in rat mesangial cells. 1996 Experientia pmid:8841513