| MeSH term | MeSH ID | Detail |
|---|---|---|
| Endotoxemia | D019446 | 27 associated lipids |
| Respirovirus Infections | D010253 | 3 associated lipids |
| Neuralgia | D009437 | 28 associated lipids |
| Sneezing | D012912 | 6 associated lipids |
| Peptic Ulcer Hemorrhage | D010438 | 4 associated lipids |
| Nasal Obstruction | D015508 | 4 associated lipids |
| Respiratory Syncytial Virus Infections | D018357 | 10 associated lipids |
| Asbestosis | D001195 | 8 associated lipids |
| Aspergillosis, Allergic Bronchopulmonary | D001229 | 2 associated lipids |
LTD4
Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Asthma, Pneumonia and Allergic asthma. The involved functions are known as inhibitors, Signal Transduction, Cell Survival, antagonists and Phosphorylation. Ltd4 often locates in Membrane, Tissue membrane, Protoplasm, Cytoplasmic matrix and membrane fraction. The associated genes with LTD4 are ALOX5 gene, UMOD gene, P4HTM gene, RAF1 gene and Homologous Gene. The related lipids are Lipopolysaccharides.
Cross Reference
Introduction
To understand associated biological information of LTD4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with LTD4?
LTD4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Allergic asthma, Virus Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with LTD4
PubChem Associated disorders and diseases
What pathways are associated with LTD4
Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTD4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with LTD4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with LTD4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with LTD4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with LTD4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with LTD4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with LTD4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tang SS et al. | Leukotriene D4 induces cognitive impairment through enhancement of CysLT₠R-mediated amyloid-β generation in mice. | 2013 | Neuropharmacology | pmid:22982445 |
| Jørgensen ST et al. | Double mutation at the putative protein kinase C phosphorylation sites Thr151 plus Thr323 in the mouse leukotrieneD4 receptor eliminates homologous desensitization. | 2013 | Cell. Physiol. Biochem. | pmid:23485744 |
| Germain AR et al. | Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23403082 |
| Zhang Z et al. | [Leukotriene D4 activates BV2 microglia in vitro]. | 2013 | Zhejiang Da Xue Xue Bao Yi Xue Ban | pmid:23801612 |
| Ramos-RamÃrez P et al. | Antigen-induced airway hyperresponsiveness in absence of broncho-obstruction in sensitized guinea pigs. | 2013 | Exp. Lung Res. | pmid:23527782 |
| Kouyama S et al. | A contraction assay system using primary cultured mouse bronchial smooth muscle cells. | 2013 | Int. Arch. Allergy Immunol. | pmid:23711859 |
| Guan WJ et al. | Impulse oscillometry for leukotriene D4 inhalation challenge in asthma. | 2013 | Respir Care | pmid:23716710 |
| Sharkey LC et al. | Differential cardiotoxicity in response to chronic doxorubicin treatment in male spontaneous hypertension-heart failure (SHHF), spontaneously hypertensive (SHR), and Wistar Kyoto (WKY) rats. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23993975 |
| Kanaoka Y et al. | Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligand. | 2013 | J. Biol. Chem. | pmid:23504326 |
| Cummings HE et al. | Cutting edge: Leukotriene C4 activates mouse platelets in plasma exclusively through the type 2 cysteinyl leukotriene receptor. | 2013 | J. Immunol. | pmid:24244016 |