Hisamatsu K et al. |
Effect of leukotriene C4 exposure on ciliated cells of the nasal mucosa. |
1996 |
Prostaglandins |
pmid:8900445
|
Chong K et al. |
Drug substance manufacture process control: application of flow injection analysis and HPLC for monitoring an enantiospecific synthesis. |
1996 |
J Pharm Biomed Anal |
pmid:8895082
|
Omori C et al. |
Eicosanoids modulate hyperpnea-induced bronchoconstriction in canine peripheral airways. |
1996 |
J. Appl. Physiol. |
pmid:8889761
|
Underwood DC et al. |
Persistent airway eosinophilia after leukotriene (LT) D4 administration in the guinea pig: modulation by the LTD4 receptor antagonist, pranlukast, or an interleukin-5 monoclonal antibody. |
1996 |
Am. J. Respir. Crit. Care Med. |
pmid:8887574
|
Burghardt JS et al. |
Lipid mediators in oxygen-induced airway remodeling and hyperresponsiveness in newborn rats. |
1996 |
Am. J. Respir. Crit. Care Med. |
pmid:8887572
|
Tai S et al. |
Effect of leukotriene D4 on tracheal mucociliary transport velocity in quails. |
1996 |
Jpn. J. Pharmacol. |
pmid:8866758
|
Wensing G et al. |
Pharmacodynamics and pharmacokinetics of BAY x 7195 aerosol, a new and selective receptor antagonist of cysteinyl-leukotrienes, in normal volunteers. |
1996 |
Br J Clin Pharmacol |
pmid:8864314
|
Fukai F et al. |
Transcellular biosynthesis of cysteinyl leukotrienes by Kupffer cell-hepatocyte cooperation in rat liver. |
1996 |
Cell Biol. Int. |
pmid:8858827
|
Abraham WM et al. |
Effect of TYB-2285 on antigen-induced airway responses in sheep. |
1996 |
Pulm Pharmacol |
pmid:8843510
|
Ochsner M |
The action of the peptidoleukotriene LTD4 on intracellular calcium in rat mesangial cells. |
1996 |
Experientia |
pmid:8841513
|
Tanaka H et al. |
The effect of a novel leukotriene C4/D4 antagonist, BAY-x-7195, on experimental allergic reactions. |
1995 Nov-Dec |
Prostaglandins |
pmid:8838238
|
Patry C et al. |
Leukotriene receptors in HL-60 cells differentiated into eosinophils, monocytes and neutrophils. |
1996 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:8832765
|
Reiss TF et al. |
Effects of montelukast (MK-0476), a new potent cysteinyl leukotriene (LTD4) receptor antagonist, in patients with chronic asthma. |
1996 |
J. Allergy Clin. Immunol. |
pmid:8828530
|
Hendeles L and Marshik PL |
Zileuton: a new therapy for asthma or just the first of a new class of drugs. |
1996 Jul-Aug |
Ann Pharmacother |
pmid:8826576
|
Herron DK et al. |
Visualization and comparison of molecular dynamics simulations of leukotriene C4, leukotriene D4, and leukotriene E4. |
1995 |
J Mol Graph |
pmid:8820302
|
Tominaga M et al. |
ONO-1078 antagonizes diarrhea-causing changes in ion transport and smooth muscle contraction induced by peptidoleukotrienes in rat and human colon in vitro. |
1996 |
J. Pharmacol. Exp. Ther. |
pmid:8819486
|
Porreca E et al. |
Cysteinyl leukotriene D4 induced vascular smooth muscle cell proliferation: a possible role in myointimal hyperplasia. |
1996 |
Thromb. Haemost. |
pmid:8819260
|
Madsen F et al. |
Challenge interval determines tachyphylaxis to aerosolized LTD4. |
1995 |
Pulm Pharmacol |
pmid:8819178
|
Rajah R et al. |
Insulin-like growth factor binding protein (IGFBP) proteases: functional regulators of cell growth. |
1995 |
Prog. Growth Factor Res. |
pmid:8817670
|
Adolfsson JL et al. |
Leukotriene D4-induced activation and translocation of the G-protein alpha i3-subunit in human epithelial cells. |
1996 |
Biochem. Biophys. Res. Commun. |
pmid:8806649
|
Shikada K and Tanaka S |
Effect of the K+ channel openers NIP-121 and cromakalim on melittin-induced relaxation of guinea-pig isolated trachea. |
1996 |
Prostaglandins |
pmid:8792445
|
Ganbo T et al. |
Leukotriene C4 inhibits ciliary activity in the presence of gamma-glutamyl transpeptidase. |
1996 |
Am. J. Physiol. |
pmid:8770059
|
Carlton RA et al. |
Preparation and characterization of polymorphs for an LTD4 antagonist, RG 12525. |
1996 |
J Pharm Sci |
pmid:8742935
|
Ishikawa J et al. |
Involvement of endogenous tachykinins in LTD4-induced airway responses. |
1996 |
Eur. Respir. J. |
pmid:8730008
|
Konno A et al. |
Role of substance P in the vascular response of nasal mucosa in nasal allergy. |
1996 |
Ann. Otol. Rhinol. Laryngol. |
pmid:8712637
|
Datta HK et al. |
Parathyroid hormone induces superoxide anion burst in the osteoclast: evidence for the direct instantaneous activation of the osteoclast by the hormone. |
1996 |
J. Endocrinol. |
pmid:8708538
|
Funayama T et al. |
Role of Leukotriene-degrading enzymes in pulmonary response to antigen infusion in sensitized guinea pigs in vivo. |
1996 |
Am. J. Respir. Cell Mol. Biol. |
pmid:8703483
|
Papayianni A et al. |
Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells. |
1996 |
J. Immunol. |
pmid:8690917
|
Sakurai S et al. |
Synthesis and thromboxane A2 antagonistic activity of [[1-aryl(or benzyl)-1-(benzenesulfonamido)methyl]phenyl]alkanoic acid derivatives. |
1996 |
Chem. Pharm. Bull. |
pmid:8681409
|
Dudek SM and Friedlander MJ |
Developmental down-regulation of LTD in cortical layer IV and its independence of modulation by inhibition. |
1996 |
Neuron |
pmid:8663986
|
Jorgensen NK et al. |
Role of LTD4 in the regulatory volume decrease response in Ehrlich ascites tumor cells. |
1996 |
J. Membr. Biol. |
pmid:8661498
|
Grönroos E et al. |
Leukotriene D4-induced mobilization of intracellular Ca2+ in epithelial cells is critically dependent on activation of the small GTP-binding protein Rho. |
1996 |
Biochem. J. |
pmid:8645211
|
Heimbürger M and Palmblad JE |
Effects of leukotriene C4 and D4, histamine and bradykinin on cytosolic calcium concentrations and adhesiveness of endothelial cells and neutrophils. |
1996 |
Clin. Exp. Immunol. |
pmid:8608646
|
Tudoric N et al. |
Effects of halothane and isoflurane on antigen- and leukotriene-D4-induced constriction of guinea pig trachea. |
1995 |
Acta Anaesthesiol Scand |
pmid:8607320
|
Weiss SR et al. |
Quenching: inhibition of development and expression of amygdala kindled seizures with low frequency stimulation. |
1995 |
Neuroreport |
pmid:8595196
|
Tasaka K et al. |
Effect of loratadine on immediate and delayed type hypersensitivity reactions. |
1995 |
Arzneimittelforschung |
pmid:8573225
|
Bonnefoi MS et al. |
Subchronic toxicity studies with the leukotriene D4 antagonist RG 12525. |
1995 |
Fundam Appl Toxicol |
pmid:8566477
|
McMillan JM and Jollow DJ |
Macrophage enhancement of galactosamine hepatotoxicity using a rat hepatocyte culture system. |
1995 |
Res. Commun. Mol. Pathol. Pharmacol. |
pmid:8564388
|
Ortiz JL et al. |
Leukotriene receptors on human pulmonary vascular endothelium. |
1995 |
Br. J. Pharmacol. |
pmid:8564195
|
Chen C et al. |
Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKC gamma mutant mice. |
1995 |
Cell |
pmid:8548809
|
Howell RE et al. |
Pulmonary pharmacology of WAY-126299A: a dual-acting 5-lipoxygenase inhibitor and leukotriene D4 antagonist. |
1995 |
Inflamm. Res. |
pmid:8548382
|
Conroy DM et al. |
Relaxant effects of pituitary adenylate cyclase activating polypeptide (PACAP) on epithelium-intact and -denuded guinea-pig trachea: a comparison with vasoactive intestinal peptide (VIP). |
1995 |
Neuropeptides |
pmid:8538872
|
Diener M and Scharrer E |
The leukotriene D4 receptor blocker, SK&F 104353, inhibits volume regulation in isolated crypts from the rat distal colon. |
1993 |
Eur. J. Pharmacol. |
pmid:8405093
|
Shikada K and Tanaka S |
Influence of epithelium on the inhibition of melittin-induced contraction of guinea-pig isolated trachea by the potassium channel opener NIP-121. |
1993 |
Br. J. Pharmacol. |
pmid:8401920
|
Metters KM and Zamboni RJ |
Photoaffinity labeling of the leukotriene D4 receptor in guinea pig lung. |
1993 |
J. Biol. Chem. |
pmid:8384212
|
Helvering LM et al. |
H-ras 61st codon activation in archival proliferative hepatic lesions isolated from female B6C3F1 mice exposed to the leukotriene D4-antagonist, LY171883. |
1994 |
Carcinogenesis |
pmid:8313527
|
Nathan RA et al. |
Inhaled ICI 204,219 blocks antigen-induced bronchoconstriction in subjects with bronchial asthma. |
1994 |
Chest |
pmid:8306751
|
Dahlén B et al. |
Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects. |
1993 |
Thorax |
pmid:8303624
|
Lee TH and Christie PE |
Leukotrienes and aspirin induced asthma. |
1993 |
Thorax |
pmid:8303620
|
Howell RE et al. |
Leukotrienes mediate antigen-induced airway hyper-reactivity in guinea pigs. |
1994 |
J. Pharmacol. Exp. Ther. |
pmid:8301576
|
Oliva D et al. |
Correlation between leukotriene D4-induced contraction and cytosolic calcium elevation: a quantitative and simultaneous evaluation in smooth muscle. |
1994 |
J. Pharmacol. Exp. Ther. |
pmid:8301553
|
Krauss AH et al. |
Determination of leukotriene effects on human neutrophil chemotaxis in vitro by differential assessment of cell motility and polarity. |
1994 |
J. Leukoc. Biol. |
pmid:8301217
|
Spada CS et al. |
Comparison of leukotriene B4 and D4 effects on human eosinophil and neutrophil motility in vitro. |
1994 |
J. Leukoc. Biol. |
pmid:8301215
|
Mastrocola T et al. |
Volume regulation in human fibroblasts: role of Ca2+ and 5-lipoxygenase products in the activation of the Cl- efflux. |
1993 |
J. Membr. Biol. |
pmid:8271272
|
Krauss AH and Woodward DF |
Polymorphonuclear leukocyte infiltration into the subretinal choroid and optic nerve in response to leukotrienes. |
1993 |
Invest. Ophthalmol. Vis. Sci. |
pmid:8258528
|
Yoshikawa S et al. |
Modulation of acetylcholine release from the myenteric plexus of guinea-pig ileum by 5-lipoxygenase metabolites of arachidonic acid. |
1993 |
Eur. J. Pharmacol. |
pmid:8223906
|
Smith LJ et al. |
Inhibition of leukotriene D4-induced bronchoconstriction in subjects with asthma: a concentration-effect study of ICI 204,219. |
1993 |
Clin. Pharmacol. Ther. |
pmid:8222486
|
Arakawa H et al. |
Leukotriene D4- and prostaglandin F2 alpha-induced airflow obstruction and airway plasma exudation in guinea-pig: role of thromboxane and its receptor. |
1993 |
Br. J. Pharmacol. |
pmid:8220872
|
Manning PJ et al. |
Exercise-induced refractoriness in asthmatic subjects involves leukotriene and prostaglandin interdependent mechanisms. |
1993 |
Am. Rev. Respir. Dis. |
pmid:8214949
|
Pawloski JR and Chapnick BM |
Antagonism of LTD4-evoked relaxation in canine renal artery and vein. |
1993 |
Am. J. Physiol. |
pmid:8214135
|
Hyun CS and Binder HJ |
Mechanism of leukotriene D4 stimulation of Cl- secretion in rat distal colon in vitro. |
1993 |
Am. J. Physiol. |
pmid:8214069
|
Han H et al. |
Effects of LTD4 and its specific antagonist L-660,711 in isolated rat hearts with chronic myocardial infarction. |
1994 |
Am. J. Physiol. |
pmid:8203604
|
Kargman S et al. |
Protein kinase C-dependent regulation of sulfidopeptide leukotriene biosynthesis and leukotriene C4 synthase in neutrophilic HL-60 cells. |
1994 |
Mol. Pharmacol. |
pmid:8190095
|
Ibe BO et al. |
Plasma and urinary leukotrienes in sickle cell disease: possible role in the inflammatory process. |
1994 |
Eur. J. Clin. Invest. |
pmid:8187808
|
Salari H et al. |
Involvement of immunologic mechanisms in a guinea pig model of western red cedar asthma. |
1994 |
J. Allergy Clin. Immunol. |
pmid:8182231
|
Abela A and Daniel EE |
Neural and myogenic effects of leukotrienes C4, D4, and E4 on canine bronchial smooth muscle. |
1994 |
Am. J. Physiol. |
pmid:8179018
|
Mion F et al. |
Short term effects of indomethacin on rat small intestinal permeability. Role of eicosanoids and platelet activating factor. |
1994 |
Gut |
pmid:8174986
|
Inamura T et al. |
Differential tissue expression of immunoreactive dehydropeptidase I, a peptidyl leukotriene metabolizing enzyme. |
1994 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:8171072
|
Dahlén B et al. |
The leukotriene-antagonist ICI-204,219 inhibits the early airway reaction to cumulative bronchial challenge with allergen in atopic asthmatics. |
1994 |
Eur. Respir. J. |
pmid:8162986
|
Welch MJ et al. |
Effect of RG 12525, a new leukotriene antagonist, on pulmonary function of asthmatic adults. |
1994 |
Ann Allergy |
pmid:8154635
|
Fauler J et al. |
Enhanced synthesis of cysteinyl leukotrienes in juvenile rheumatoid arthritis. |
1994 |
Arthritis Rheum. |
pmid:8129769
|
Ramis I et al. |
Application of totally automated on-line sample clean up system for extraction and high-performance liquid chromatography separation of peptide leukotrienes. |
1993 Nov-Dec |
J Pharm Biomed Anal |
pmid:8123725
|
Weide I et al. |
Intravascular cysteinyl-leukotriene formation by clotting whole human blood. Evidence from clamped umbilical vein segments and thrombus specimens. |
1993 |
Thromb. Res. |
pmid:8122190
|
Ellis JL and Undem BJ |
Role of cysteinyl-leukotrienes and histamine in mediating intrinsic tone in isolated human bronchi. |
1994 |
Am. J. Respir. Crit. Care Med. |
pmid:8111568
|
Tudorić N et al. |
Phosphoramidon augments contraction of guinea pig tracheal smooth muscle induced by histamine and leukotriene-D4. |
1994 |
Int. Arch. Allergy Immunol. |
pmid:8111247
|
Nakazawa T et al. |
Leukotriene D4-induced mucosal damage during long observation periods in vitro. |
1994 |
Prostaglandins |
pmid:8066186
|
An S et al. |
Molecular cloning of sheep lung dipeptidase: a glycosyl phosphatidylinositol-anchored ectoenzyme that converts leukotriene D4 to leukotriene E4. |
1994 |
Biochim. Biophys. Acta |
pmid:8054366
|
Diener M and Scharrer E |
The effect of short-chain fatty acids on Cl- and K+ conductance in rat colonic crypts. |
1994 |
Pflugers Arch. |
pmid:8052516
|
Metters KM et al. |
Characterization of specific binding sites for cysteinyl leukotrienes in sheep lung. |
1994 |
J. Pharmacol. Exp. Ther. |
pmid:8035338
|
Underwood DC et al. |
Comparison of phosphodiesterase III, IV and dual III/IV inhibitors on bronchospasm and pulmonary eosinophil influx in guinea pigs. |
1994 |
J. Pharmacol. Exp. Ther. |
pmid:8035322
|
Herd CM et al. |
Effect of a 5-lipoxygenase inhibitor and leukotriene antagonist (PF 5901) on antigen-induced airway responses in neonatally immunized rabbits. |
1994 |
Br. J. Pharmacol. |
pmid:8032653
|
Hoheisel U and Mense S |
Leukotriene D4 depresses the mechanosensitivity of group III and IV muscle receptors in the rat. |
1994 |
Neuroreport |
pmid:8025261
|
Chan CC et al. |
Leukotriene D4-induced increases in cytosolic calcium in THP-1 cells: dependence on extracellular calcium and inhibition with selective leukotriene D4 receptor antagonists. |
1994 |
J. Pharmacol. Exp. Ther. |
pmid:8014876
|
Diamant Z et al. |
Effect of an inhaled neutral endopeptidase inhibitor, thiorphan, on airway responsiveness to leukotriene D4 in normal and asthmatic subjects. |
1994 |
Eur. Respir. J. |
pmid:8013602
|
Chan CC et al. |
Evaluation of bronchoconstriction induced by neurokinins and its inhibition by selective nonpeptide antagonists in conscious guinea pigs, using a double-chamber plethysmograph technique. |
1994 |
Can. J. Physiol. Pharmacol. |
pmid:8012892
|
Dandurand RJ et al. |
In vitro allergic bronchoconstriction in the brown Norway rat. |
1994 |
Am. J. Respir. Crit. Care Med. |
pmid:8004305
|
Callaghan DH et al. |
Respiratory tract eicosanoid measurement using microdialysis sampling and GC/MS detection. |
1994 |
Pulm Pharmacol |
pmid:8003850
|
Kelley M et al. |
Induction of peroxisomal enzymes by a tetrazole-substituted 2-quinolinylmethoxy leukotriene D4 antagonist. |
1994 |
Fundam Appl Toxicol |
pmid:7982537
|
Arakawa H et al. |
Effect of maturation on airway plasma exudation induced by eicosanoids in guinea pig. |
1994 |
Eur. J. Pharmacol. |
pmid:7982451
|
Furukawa K et al. |
Simplified sulfidoleukotriene ELISA using LTD4-conjugated phosphatase for the study of allergen-induced leukotriene generation by isolated mononuclear cells and diluted whole blood. |
1994 May-Jun |
J Investig Allergol Clin Immunol |
pmid:7981880
|
Nishida T et al. |
Effects of leukotriene D4 on myocardial blood flow and high energy phosphate concentration in anesthetized dogs. |
1994 |
Jpn. Circ. J. |
pmid:7967000
|
Leier I et al. |
The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates. |
1994 |
J. Biol. Chem. |
pmid:7961706
|
Hirata F et al. |
IL-1 beta regulates the expression of the Gi2 alpha gene via lipid mediators in guinea pig tracheal muscle. |
1994 |
Biochem. Biophys. Res. Commun. |
pmid:7945342
|
Thioudellet C et al. |
Molecular and functional characterization of recombinant human gamma-glutamyltransferase. Coupling of its activity to glutathione levels in V79 cells. |
1994 |
Eur. J. Biochem. |
pmid:7913033
|
Sparatore A and Sparatore F |
Preparation and pharmacological activities of 10-homolupinanoyl-2-R-phenothiazines. |
1994 |
Farmaco |
pmid:7910463
|
Tanaka T et al. |
Protective effect of peptide leukotriene antagonist on renal failure induced by a tourniquet in rabbits. |
1995 |
Forensic Sci. Int. |
pmid:7875619
|
Ganbo T et al. |
Inhibition of mucociliary clearance of the eustachian tube by leukotrienes C4 and D4. |
1995 |
Ann. Otol. Rhinol. Laryngol. |
pmid:7872607
|
Wensing G et al. |
Effect of BAY x 7195, an oral receptor antagonist of cysteinyl-leukotrienes, on leukotriene D4-induced bronchoconstriction in normal volunteers. |
1994 |
Eur. J. Clin. Pharmacol. |
pmid:7867675
|
Patel JP et al. |
Beneficial effects of combined thromboxane and leukotriene receptor antagonism in hemorrhagic shock. |
1995 |
Crit. Care Med. |
pmid:7867347
|
Petric R and Ford-Hutchinson AW |
Elevated cysteinyl leukotriene excretion in experimental glomerulonephritis. |
1994 |
Kidney Int. |
pmid:7853790
|