Germain AR et al. |
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells. |
2013 |
Bioorg. Med. Chem. Lett. |
pmid:23403082
|
Chambers RJ et al. |
Development of new chromanol antagonists of leukotriene D4. |
1998 |
Bioorg. Med. Chem. Lett. |
pmid:9873435
|
Macdonald D et al. |
Substituted 2,2-bisaryl-bicycloheptanes as novel and potent inhibitors of 5-lipoxygenase activating protein. |
2008 |
Bioorg. Med. Chem. Lett. |
pmid:18276139
|
Bouchelouche K et al. |
The action of cysteinyl-leukotrienes on intracellular calcium mobilization in human detrusor myocytes. |
2001 |
BJU Int. |
pmid:11350414
|
Lärfars G et al. |
Activation of nitric oxide release and oxidative metabolism by leukotrienes B4, C4, and D4 in human polymorphonuclear leukocytes. |
1999 |
Blood |
pmid:9949184
|
Dannull J et al. |
Leukotriene C4 induces migration of human monocyte-derived dendritic cells without loss of immunostimulatory function. |
2012 |
Blood |
pmid:22323449
|
Jiang Y et al. |
CysLT2 receptors interact with CysLT1 receptors and down-modulate cysteinyl leukotriene dependent mitogenic responses of mast cells. |
2007 |
Blood |
pmid:17693579
|
Bautz F et al. |
Chemotaxis and transendothelial migration of CD34(+) hematopoietic progenitor cells induced by the inflammatory mediator leukotriene D4 are mediated by the 7-transmembrane receptor CysLT1. |
2001 |
Blood |
pmid:11369634
|
Ito Y et al. |
Guinea pig cysteinyl leukotriene receptor 2 (gpCysLT2) mediates cell proliferation and intracellular calcium mobilization by LTC4 and LTD4. |
2008 |
BMB Rep |
pmid:18315950
|
Bellamkonda K et al. |
The eicosanoids leukotriene D4 and prostaglandin E2 promote the tumorigenicity of colon cancer-initiating cells in a xenograft mouse model. |
2016 |
BMC Cancer |
pmid:27388564
|
Linares Segovia B et al. |
Parameters of lung inflammation in asthmatic as compared to healthy children in a contaminated city. |
2014 |
BMC Pulm Med |
pmid:25000942
|
Schwartz JI et al. |
Oral pharmacokinetics and food interaction of the leukotriene D4 receptor antagonist verlukast. |
1993 |
Br J Clin Pharmacol |
pmid:12959296
|
Wensing G et al. |
Pharmacodynamics and pharmacokinetics of BAY x 7195 aerosol, a new and selective receptor antagonist of cysteinyl-leukotrienes, in normal volunteers. |
1996 |
Br J Clin Pharmacol |
pmid:8864314
|
Wood-Baker R et al. |
The reproducibility and effect on non-specific airway responsiveness of inhaled prostaglandin D2 and leukotriene D4 in asthmatic subjects. |
1995 |
Br J Clin Pharmacol |
pmid:7742148
|
Mezhybovska M et al. |
Beta-catenin is involved in alterations in mitochondrial activity in non-transformed intestinal epithelial and colon cancer cells. |
2009 |
Br. J. Cancer |
pmid:19826421
|
Taylor-Clark TE et al. |
Leukotriene D4 increases the excitability of capsaicin-sensitive nasal sensory nerves to electrical and chemical stimuli. |
2008 |
Br. J. Pharmacol. |
pmid:18500362
|
Murray J et al. |
Role of leukotrienes in the regulation of human granulocyte behaviour: dissociation between agonist-induced activation and retardation of apoptosis. |
2003 |
Br. J. Pharmacol. |
pmid:12770944
|
Mazzetti L et al. |
The ACh-induced contraction in rat aortas is mediated by the Cys Lt1 receptor via intracellular calcium mobilization in smooth muscle cells. |
2003 |
Br. J. Pharmacol. |
pmid:12598425
|
Francis HP et al. |
The effects of a novel sulphidopeptide leukotriene antagonist, BAY x7195, against elicited bronchoconstriction in the anaesthetized guinea-pig. |
1998 |
Br. J. Pharmacol. |
pmid:9484852
|
Capra V et al. |
Pharmacological characterization of the cysteinyl-leukotriene antagonists CGP 45715A (iralukast) and CGP 57698 in human airways in vitro. |
1998 |
Br. J. Pharmacol. |
pmid:9504401
|
Shahbazian A et al. |
Differential peristaltic motor effects of prostanoid (DP, EP, IP, TP) and leukotriene receptor agonists in the guinea-pig isolated small intestine. |
2002 |
Br. J. Pharmacol. |
pmid:12429577
|
Walch L et al. |
Pharmacological evidence for a novel cysteinyl-leukotriene receptor subtype in human pulmonary artery smooth muscle. |
2002 |
Br. J. Pharmacol. |
pmid:12466244
|
Bäck M et al. |
An alternative pathway for metabolism of leukotriene D(4): effects on contractions to cysteinyl-leukotrienes in the guinea-pig trachea. |
2001 |
Br. J. Pharmacol. |
pmid:11487525
|
Wunder F et al. |
Pharmacological characterization of the first potent and selective antagonist at the cysteinyl leukotriene 2 (CysLT(2)) receptor. |
2010 |
Br. J. Pharmacol. |
pmid:20423349
|
Tsang F et al. |
Effects of mitogen-activated protein kinase kinase inhibitor PD 098059 on antigen challenge of guinea-pig airways in vitro. |
1998 |
Br. J. Pharmacol. |
pmid:9776345
|
Liu YC et al. |
Effects of the cysteinyl leukotriene receptor antagonists pranlukast and zafirlukast on tracheal mucus secretion in ovalbumin-sensitized guinea-pigs in vitro. |
1998 |
Br. J. Pharmacol. |
pmid:9647482
|
Ishimura M et al. |
Effects of KP-496, a novel dual antagonist at the cysteinyl leukotriene receptor 1 and the thromboxane A(2) receptor, on airway obstruction in guinea pigs. |
2008 |
Br. J. Pharmacol. |
pmid:18037905
|
Arakawa H et al. |
Leukotriene D4- and prostaglandin F2 alpha-induced airflow obstruction and airway plasma exudation in guinea-pig: role of thromboxane and its receptor. |
1993 |
Br. J. Pharmacol. |
pmid:8220872
|
Fujimura M et al. |
A partial involvement of histamine in ultrasonically nebulized distilled water-induced bronchoconstriction in guinea-pigs. |
1998 |
Br. J. Pharmacol. |
pmid:9831931
|
Hele DJ et al. |
Mediator involvement in antigen-induced bronchospasm and microvascular leakage in the airways of ovalbumin sensitized Brown Norway rats. |
2001 |
Br. J. Pharmacol. |
pmid:11159698
|
Snetkov VA et al. |
Mechanisms of leukotriene D4-induced constriction in human small bronchioles. |
2001 |
Br. J. Pharmacol. |
pmid:11350860
|
Herd CM et al. |
Effect of a 5-lipoxygenase inhibitor and leukotriene antagonist (PF 5901) on antigen-induced airway responses in neonatally immunized rabbits. |
1994 |
Br. J. Pharmacol. |
pmid:8032653
|
Shikada K and Tanaka S |
Influence of epithelium on the inhibition of melittin-induced contraction of guinea-pig isolated trachea by the potassium channel opener NIP-121. |
1993 |
Br. J. Pharmacol. |
pmid:8401920
|
Ortiz JL et al. |
Leukotriene receptors on human pulmonary vascular endothelium. |
1995 |
Br. J. Pharmacol. |
pmid:8564195
|
Sermasi E et al. |
Long term depression is expressed during postnatal development in rat visual cortex: a role for visual experience. |
1999 |
Brain Res. Dev. Brain Res. |
pmid:10064875
|
Jones TR et al. |
Pharmacology of montelukast sodium (Singulair), a potent and selective leukotriene D4 receptor antagonist. |
1995 |
Can. J. Physiol. Pharmacol. |
pmid:7621356
|
Yamashita T and Kokubun S |
Nonselective cationic currents activated by acetylcholine in swine tracheal smooth muscle cells. |
1999 |
Can. J. Physiol. Pharmacol. |
pmid:10588484
|
Nagase T and Ludwig MS |
Antigen-induced responses in lung parenchymal strips during sinusoidal oscillation. |
1998 |
Can. J. Physiol. Pharmacol. |
pmid:9635157
|
Chan CC et al. |
Evaluation of bronchoconstriction induced by neurokinins and its inhibition by selective nonpeptide antagonists in conscious guinea pigs, using a double-chamber plethysmograph technique. |
1994 |
Can. J. Physiol. Pharmacol. |
pmid:8012892
|
Nagayama S et al. |
Increased sensitivity to vincristine of MDR cells by the leukotriene D4 receptor antagonist, ONO-1078. |
1998 |
Cancer Lett. |
pmid:9751271
|
Nielsen CK et al. |
A novel localization of the G-protein-coupled CysLT1 receptor in the nucleus of colorectal adenocarcinoma cells. |
2005 |
Cancer Res. |
pmid:15705869
|
Helvering LM et al. |
H-ras 61st codon activation in archival proliferative hepatic lesions isolated from female B6C3F1 mice exposed to the leukotriene D4-antagonist, LY171883. |
1994 |
Carcinogenesis |
pmid:8313527
|
Parhamifar L et al. |
Activation of cPLA2 is required for leukotriene D4-induced proliferation in colon cancer cells. |
2005 |
Carcinogenesis |
pmid:15975962
|
Zhou G et al. |
Atorvastatin reduces plaque vulnerability in an atherosclerotic rabbit model by altering the 5-lipoxygenase pathway. |
2010 |
Cardiology |
pmid:20234134
|
Finkensieper A et al. |
The 5-lipoxygenase pathway regulates vasculogenesis in differentiating mouse embryonic stem cells. |
2010 |
Cardiovasc. Res. |
pmid:19965960
|
Chen C et al. |
Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKC gamma mutant mice. |
1995 |
Cell |
pmid:8548809
|
Robbiani DF et al. |
The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes. |
2000 |
Cell |
pmid:11114332
|
Fukai F et al. |
Transcellular biosynthesis of cysteinyl leukotrienes by Kupffer cell-hepatocyte cooperation in rat liver. |
1996 |
Cell Biol. Int. |
pmid:8858827
|
Gorenne I et al. |
Antigen stimulation of human pulmonary smooth muscle: an in vitro model of inflammation. |
1996 |
Cell Biol. Toxicol. |
pmid:9034615
|
Grönroos E et al. |
Leukotriene D4 induces a rapid increase in cAMP in the human epithelial cell line, Int 407: a potential role for this signal in the regulation of calcium influx through the plasma membrane. |
1998 |
Cell Calcium |
pmid:9793684
|