MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.
To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin
MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Qi F et al. | Anti-inflammatory effects of isorhamnetin on LPS-stimulated human gingival fibroblasts by activating Nrf2 signaling pathway. | 2018 | Microb. Pathog. | pmid:29704670 |
Lu X et al. | Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice. | 2018 | Biomed. Pharmacother. | pmid:29684859 |
Ressaissi A et al. | Isorhamnetin derivatives and piscidic acid for hypercholesterolemia: cholesterol permeability, HMG-CoA reductase inhibition, and docking studies. | 2017 | Arch. Pharm. Res. | pmid:28936788 |
Shi W et al. | Bioactive flavonoids from Flos Sophorae. | 2017 | J Nat Med | pmid:28357634 |
Burak C et al. | Higher plasma quercetin levels following oral administration of an onion skin extract compared with pure quercetin dihydrate in humans. | 2017 | Eur J Nutr | pmid:26482244 |
Mikulic-Petkovsek M et al. | Bioactive Components and Antioxidant Capacity of Fruits from Nine Sorbus Genotypes. | 2017 | J. Food Sci. | pmid:28182841 |
Östlund J et al. | In vitro inhibition of human CYP2E1 and CYP3A by quercetin and myricetin in hepatic microsomes is not gender dependent. | 2017 | Toxicology | pmid:28232125 |
Wang JY et al. | Network pharmacological mechanisms of Vernonia anthelmintica (L.) in the treatment of vitiligo: Isorhamnetin induction of melanogenesis via up-regulation of melanin-biosynthetic genes. | 2017 | BMC Syst Biol | pmid:29145845 |
Antunes-Ricardo M et al. | Bioaccessibility, Intestinal Permeability and Plasma Stability of Isorhamnetin Glycosides from Opuntia ficus-indica (L.). | 2017 | Int J Mol Sci | pmid:28829356 |
Li J et al. | Isorhamnetin inhibits IL‑1β‑induced expression of inflammatory mediators in human chondrocytes. | 2017 | Mol Med Rep | pmid:28731170 |