3-O-Methylquercetin

3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.

Cross Reference

Introduction

To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 3-O-Methylquercetin?

3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin

MeSH term MeSH ID Detail
Cell Transformation, Neoplastic D002471 126 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with 3-O-Methylquercetin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 3-O-Methylquercetin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 3-O-Methylquercetin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 3-O-Methylquercetin?

There are no associated biomedical information in the current reference collection.

What genes are associated with 3-O-Methylquercetin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 3-O-Methylquercetin?

Streptozotocin Diabetes

Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with 3-O-Methylquercetin

Download all related citations
Per page 10 20 50 100 | Total 307
Authors Title Published Journal PubMed Link
Gray D et al. Determination of flavonol aglycones in Ginkgo biloba dietary supplement crude materials and finished products by high-performance liquid chromatography: single laboratory validation. 2005 May-Jun J AOAC Int pmid:16001841
Jiang JS et al. Mechanisms of suppression of nitric oxide production by 3-O-methylquercetin in RAW 264.7 cells. 2006 J Ethnopharmacol pmid:16213685
Küpeli E et al. Effect of Cistus laurifolius L. leaf extracts and flavonoids on acetaminophen-induced hepatotoxicity in mice. 2006 J Ethnopharmacol pmid:16216454
Chang TK et al. Effect of Ginkgo biloba extract on procarcinogen-bioactivating human CYP1 enzymes: identification of isorhamnetin, kaempferol, and quercetin as potent inhibitors of CYP1B1. 2006 Toxicol. Appl. Pharmacol. pmid:16226778
Schulz HU et al. Investigation of pharmacokinetic data of hypericin, pseudohypericin, hyperforin and the flavonoids quercetin and isorhamnetin revealed from single and multiple oral dose studies with a hypericum extract containing tablet in healthy male volunteers. 2005 Arzneimittelforschung pmid:16294501
Kim BG et al. Multiple regiospecific methylations of a flavonoid by plant O-methyltransferases expressed in E. coli. 2005 Biotechnol. Lett. pmid:16328980
Dragoni S et al. Red wine alcohol promotes quercetin absorption and directs its metabolism towards isorhamnetin and tamarixetin in rat intestine in vitro. 2006 Br. J. Pharmacol. pmid:16444288
Romani A et al. HPLC-DAD/MS characterization of flavonoids and hydroxycinnamic derivatives in turnip tops (Brassica rapa L. Subsp. sylvestris L.). 2006 J. Agric. Food Chem. pmid:16478258
Zu Y et al. Simultaneous determination of catechin, rutin, quercetin kaempferol and isorhamnetin in the extract of sea buckthorn (Hippophae rhamnoides L.) leaves by RP-HPLC with DAD. 2006 J Pharm Biomed Anal pmid:16520013
Lall N et al. Antiviral and antituberculous activity of Helichrysum melanacme constituents. 2006 Fitoterapia pmid:16529879
Hyun SK et al. Isorhamnetin glycosides with free radical and ONOO-scavenging activities from the stamens of Nelumbo nucifera. 2006 Arch. Pharm. Res. pmid:16681033
Teng BS et al. In vitro anti-tumor activity of isorhamnetin isolated from Hippophae rhamnoides L. against BEL-7402 cells. 2006 Pharmacol. Res. pmid:16765054
Rochfort SJ et al. Characterization of flavonol conjugates in immature leaves of pak choi [Brassica rapa L. Ssp. chinensis L. (Hanelt.)] by HPLC-DAD and LC-MS/MS. 2006 J. Agric. Food Chem. pmid:16787039
Sadhu SK et al. Prostaglandin inhibitory and antioxidant components of Cistus laurifolius, a Turkish medicinal plant. 2006 J Ethnopharmacol pmid:16814498
Bao M and Lou Y Flavonoids from seabuckthorn protect endothelial cells (EA.hy926) from oxidized low-density lipoprotein induced injuries via regulation of LOX-1 and eNOS expression. 2006 J. Cardiovasc. Pharmacol. pmid:16891912
Phadungkit M and Luanratana O Anti-Salmonella activity of constituents of Ardisia elliptica Thunb. 2006 Nat. Prod. Res. pmid:16901814
Ding S et al. Quantitative determination of major active components in Ginkgo biloba dietary supplements by liquid chromatography/mass spectrometry. 2006 Rapid Commun. Mass Spectrom. pmid:16921563
Hubbard GP et al. Ingestion of onion soup high in quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in man: a pilot study. 2006 Br. J. Nutr. pmid:16925853
Shukla SK et al. Protection from radiation-induced mitochondrial and genomic DNA damage by an extract of Hippophae rhamnoides. 2006 Environ. Mol. Mutagen. pmid:16948057
Bao M and Lou Y Isorhamnetin prevent endothelial cell injuries from oxidized LDL via activation of p38MAPK. 2006 Eur. J. Pharmacol. pmid:16963021
Suomela JP et al. Absorption of flavonols derived from sea buckthorn (Hippophaë rhamnoides L.) and their effect on emerging risk factors for cardiovascular disease in humans. 2006 J. Agric. Food Chem. pmid:16968106
Marie D et al. Constituents of Psiadia terebinthina A.J. Scott, an endemic Asteraceae from Mauritius. 2006 Nat. Prod. Res. pmid:17127504
Lan K et al. Quantitative determination of isorhamnetin, quercetin and kaempferol in rat plasma by liquid chromatography with electrospray ionization tandem mass spectrometry and its application to the pharmacokinetic study of isorhamnetin. 2007 Rapid Commun. Mass Spectrom. pmid:17154349
Ma G et al. The flavonoid component isorhamnetin in vitro inhibits proliferation and induces apoptosis in Eca-109 cells. 2007 Chem. Biol. Interact. pmid:17368593
Gray D et al. Evaluation of a method to determine flavonol aglycones in Ginkgo biloba dietary supplement crude materials and finished products by high-performance liquid chromatography: collaborative study. 2007 Jan-Feb J AOAC Int pmid:17373435
Sanchez M et al. Quercetin and isorhamnetin prevent endothelial dysfunction, superoxide production, and overexpression of p47phox induced by angiotensin II in rat aorta. 2007 J. Nutr. pmid:17374653
Chawla R et al. Radioprotective and antioxidant activity of fractionated extracts of berries of Hippophae rhamnoides. 2007 J Med Food pmid:17472473
Wang D et al. Preparation and characterization of solid lipid nanoparticles loaded with total flavones of Hippophae rhamnoides (TFH). 2007 Mar-Apr PDA J Pharm Sci Technol pmid:17479719
Park J et al. Onion flesh and onion peel enhance antioxidant status in aged rats. 2007 J. Nutr. Sci. Vitaminol. pmid:17484375
Küpeli E and Yesilada E Flavonoids with anti-inflammatory and antinociceptive activity from Cistus laurifolius L. leaves through bioassay-guided procedures. 2007 J Ethnopharmacol pmid:17540523
Fasolo D et al. Validation of an isocratic LC method for determination of quercetin and methylquercetin in topical nanoemulsions. 2007 J Pharm Biomed Anal pmid:17540529
Tundis R et al. Inhibitory effects on the digestive enzyme alpha-amylase of three Salsola species (Chenopodiaceae) in vitro. 2007 Pharmazie pmid:17663200
Suzuki H et al. Metabolic profiling of flavonoids in Lotus japonicus using liquid chromatography Fourier transform ion cyclotron resonance mass spectrometry. 2008 Phytochemistry pmid:17669449
Jiang JS et al. Potent suppressive effects of 3-O-methylquercetin 5,7,3',4'-O-tetraacetate on ovalbumin-induced airway hyperresponsiveness. 2007 Planta Med. pmid:17823872
Steffen Y et al. Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase. 2008 Arch. Biochem. Biophys. pmid:17996190
Tamura M et al. Effect of pectin enhancement on plasma quercetin and fecal flora in rutin-supplemented mice. 2007 J. Food Sci. pmid:18034749
Neznanov N et al. Quercetinase pirin makes poliovirus replication resistant to flavonoid quercetin. 2008 DNA Cell Biol. pmid:18067462
Kim JY et al. In vitro anti-inflammatory activity of 3-O-methyl-flavones isolated from Siegesbeckia glabrescens. 2008 Bioorg. Med. Chem. Lett. pmid:18178435
Holzschuh MH et al. Thermal and photo stability of phenolic constituents of an Achyrocline satureioides spray-dried powder. 2007 Pharmazie pmid:18214340
Hämäläinen M et al. Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages. 2007 Mediators Inflamm. pmid:18274639
Sobolev VS et al. Spermidine and flavonoid conjugates from peanut (Arachis hypogaea) flowers. 2008 J. Agric. Food Chem. pmid:18412366
Romero M et al. Quercetin inhibits vascular superoxide production induced by endothelin-1: Role of NADPH oxidase, uncoupled eNOS and PKC. 2009 Atherosclerosis pmid:18436224
Paulke A et al. St. John's wort flavonoids and their metabolites show antidepressant activity and accumulate in brain after multiple oral doses. 2008 Pharmazie pmid:18468390
Winterbone MS et al. Physiologically relevant metabolites of quercetin have no effect on adhesion molecule or chemokine expression in human vascular smooth muscle cells. 2009 Atherosclerosis pmid:18489909
Vukics V et al. Analysis of heartsease (Viola tricolor L.) flavonoid glycosides by micro-liquid chromatography coupled to multistage mass spectrometry. 2008 J Chromatogr A pmid:18514209
Wang XM et al. Two new flavonol glycosides from Sarcopyramis bodinieri var. delicate. 2008 Molecules pmid:18596665
Papiez MA et al. The changes of antioxidant defense system caused by quercetin administration do not lead to DNA damage and apoptosis in the spleen and bone marrow cells of rats. 2008 Food Chem. Toxicol. pmid:18602965
Lee HJ et al. Mitochondria-cytochrome C-caspase-9 cascade mediates isorhamnetin-induced apoptosis. 2008 Cancer Lett. pmid:18617322
Olszewska M Separation of quercetin, sexangularetin, kaempferol and isorhamnetin for simultaneous HPLC determination of flavonoid aglycones in inflorescences, leaves and fruits of three Sorbus species. 2008 J Pharm Biomed Anal pmid:18635332
Bieger J et al. Tissue distribution of quercetin in pigs after long-term dietary supplementation. 2008 J. Nutr. pmid:18641184