3-O-Methylquercetin

3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.

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Introduction

To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 3-O-Methylquercetin?

3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin

MeSH term MeSH ID Detail
Cell Transformation, Neoplastic D002471 126 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with 3-O-Methylquercetin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 3-O-Methylquercetin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 3-O-Methylquercetin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 3-O-Methylquercetin?

There are no associated biomedical information in the current reference collection.

What genes are associated with 3-O-Methylquercetin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 3-O-Methylquercetin?

Streptozotocin Diabetes

Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with 3-O-Methylquercetin

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Authors Title Published Journal PubMed Link
Egert S et al. Daily quercetin supplementation dose-dependently increases plasma quercetin concentrations in healthy humans. 2008 J. Nutr. pmid:18716159
Lee SU et al. Flavonoid content in fresh, home-processed, and light-exposed onions and in dehydrated commercial onion products. 2008 J. Agric. Food Chem. pmid:18759442
Lodi F et al. Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta. 2009 Atherosclerosis pmid:18801486
Liu AL et al. Study of the electrochemical behavior of isorhamnetin on a glassy carbon electrode and its application. 2008 Talanta pmid:18804639
Lee J et al. Isorhamnetin represses adipogenesis in 3T3-L1 cells. 2009 Obesity (Silver Spring) pmid:18948972
Lan K et al. Intra-herb pharmacokinetics interaction between quercetin and isorhamentin. 2008 Acta Pharmacol. Sin. pmid:18954533
Boesch-Saadatmandi C et al. Effect of apoE genotype and dietary quercetin on blood lipids and TNF-alpha levels in apoE3 and apoE4 targeted gene replacement mice. 2009 Br. J. Nutr. pmid:18986596
Kawai Y et al. Different profiles of quercetin metabolites in rat plasma: comparison of two administration methods. 2009 Biosci. Biotechnol. Biochem. pmid:19270373
Okoko T and Oruambo IF Inhibitory activity of quercetin and its metabolite on lipopolysaccharide-induced activation of macrophage U937 cells. 2009 Food Chem. Toxicol. pmid:19271315
Krenn L et al. Contribution of methylated exudate flavonoids to the anti-inflammatory activity of Grindelia robusta. 2009 Fitoterapia pmid:19278665
Larmo PS et al. Effect of a low dose of sea buckthorn berries on circulating concentrations of cholesterol, triacylglycerols, and flavonols in healthy adults. 2009 Eur J Nutr pmid:19288149
Wang Z et al. Simultaneous determination of six herbal components in intestinal perfusate by high-performance liquid chromatography. 2009 Biomed. Chromatogr. pmid:19309764
Pengfei L et al. Antioxidant properties of isolated isorhamnetin from the sea buckthorn marc. 2009 Plant Foods Hum Nutr pmid:19444611
Li L et al. Identification and bioactivities of resveratrol oligomers and flavonoids from Carex folliculata seeds. 2009 J. Agric. Food Chem. pmid:19627089
Hölscher D et al. Matrix-free UV-laser desorption/ionization (LDI) mass spectrometric imaging at the single-cell level: distribution of secondary metabolites of Arabidopsis thaliana and Hypericum species. 2009 Plant J. pmid:19732382
Cao J et al. The relationship between fasting plasma concentrations of selected flavonoids and their ordinary dietary intake. 2010 Br. J. Nutr. pmid:19747418
Søltoft M et al. Pressurised liquid extraction of flavonoids in onions. Method development and validation. 2009 Talanta pmid:19782226
Matsukawa N et al. Nondigestible saccharides suppress the bacterial degradation of quercetin aglycone in the large intestine and enhance the bioavailability of quercetin glucoside in rats. 2009 J. Agric. Food Chem. pmid:19807098
Zhang N et al. Isorhamnetin protects rat ventricular myocytes from ischemia and reperfusion injury. 2011 Exp. Toxicol. Pathol. pmid:19815400
Lee J et al. Isorhamnetin-induced anti-adipogenesis is mediated by stabilization of beta-catenin protein. 2010 Life Sci. pmid:20097210
Fasolo D et al. Development of topical nanoemulsions containing quercetin and 3-O-methylquercetin. 2009 Pharmazie pmid:20099516
Olsson ME et al. Quercetin and isorhamnetin in sweet and red cultivars of onion (Allium cepa L.) at harvest, after field curing, heat treatment, and storage. 2010 J. Agric. Food Chem. pmid:20099844
An D et al. Changes of metabolic profiles in urine after oral administration of quercetin in rats. 2010 Food Chem. Toxicol. pmid:20304023
Rupasinghe HP et al. Absorption and tissue distribution of dietary quercetin and quercetin glycosides of apple skin in broiler chickens. 2010 J. Sci. Food Agric. pmid:20393998
Ozgen U et al. A new sulfated alpha-ionone glycoside from Sonchus erzincanicus Matthews. 2010 Molecules pmid:20428066
Xia F et al. Simultaneous determination of copper, lead, and cadmium at hexagonal mesoporous silica immobilized quercetin modified carbon paste electrode. 2010 J Autom Methods Manag Chem pmid:20445747
Rangel-Ordóñez L et al. Plasma levels and distribution of flavonoids in rat brain after single and repeated doses of standardized Ginkgo biloba extract EGb 761®. 2010 Planta Med. pmid:20486074
Park S and Choi J Inhibition of beta-catenin/Tcf signaling by flavonoids. 2010 J. Cell. Biochem. pmid:20564233
Qu L et al. Protective effects of flavonoids against oxidative stress induced by simulated microgravity in SH-SY5Y cells. 2010 Neurochem. Res. pmid:20571914
Boesch-Saadatmandi C et al. Effect of quercetin and its metabolites isorhamnetin and quercetin-3-glucuronide on inflammatory gene expression: role of miR-155. 2011 J. Nutr. Biochem. pmid:20579867
Chen ZP et al. Comparative pharmacokinetics and bioavailability studies of quercetin, kaempferol and isorhamnetin after oral administration of Ginkgo biloba extracts, Ginkgo biloba extract phospholipid complexes and Ginkgo biloba extract solid dispersions in rats. 2010 Fitoterapia pmid:20603197
Choi KC et al. Inhibitory effects of quercetin on aflatoxin B1-induced hepatic damage in mice. 2010 Food Chem. Toxicol. pmid:20621152
Garrido I et al. Targeted analysis of conjugated and microbial-derived phenolic metabolites in human urine after consumption of an almond skin phenolic extract. 2010 J. Nutr. pmid:20739450
Fernández-López JA et al. Determination of antioxidant constituents in cactus pear fruits. 2010 Plant Foods Hum Nutr pmid:20811778
Wang J et al. Preparative separation of phenolic compounds from Halimodendron halodendron by high-speed counter-current chromatography. 2010 Molecules pmid:20877205
Jaramillo S et al. The flavonol isorhamnetin exhibits cytotoxic effects on human colon cancer cells. 2010 J. Agric. Food Chem. pmid:20923189
Holzschuh MH et al. Identification and stability of a new bichalcone in Achyrocline satureioides spray dried powder. 2010 Pharmazie pmid:21038841
Lee J and Mitchell AE Quercetin and isorhamnetin glycosides in onion (Allium cepa L.): varietal comparison, physical distribution, coproduct evaluation, and long-term storage stability. 2011 J. Agric. Food Chem. pmid:21244009
Wei Y et al. Separation of patuletin-3-O-glucoside, astragalin, quercetin, kaempferol and isorhamnetin from Flaveria bidentis (L.) Kuntze by elution-pump-out high-performance counter-current chromatography. 2011 J Chromatogr A pmid:21329934
Kim JE et al. Isorhamnetin suppresses skin cancer through direct inhibition of MEK1 and PI3-K. 2011 Cancer Prev Res (Phila) pmid:21330379
Lee SH et al. Persicaria hydropiper (L.) spach and its flavonoid components, isoquercitrin and isorhamnetin, activate the Wnt/β-catenin pathway and inhibit adipocyte differentiation of 3T3-L1 cells. 2011 Phytother Res pmid:21413092
Vitalini S et al. Primula spectabilis Tratt. aerial parts: morphology, volatile compounds and flavonoids. 2011 Phytochemistry pmid:21612805
Rajbhandari R et al. Determination of cranberry phenolic metabolites in rats by liquid chromatography-tandem mass spectrometry. 2011 J. Agric. Food Chem. pmid:21634376
Egert S et al. Enriched cereal bars are more effective in increasing plasma quercetin compared with quercetin from powder-filled hard capsules. 2012 Br. J. Nutr. pmid:21774840
Surco-Laos F et al. Effects of O-methylated metabolites of quercetin on oxidative stress, thermotolerance, lifespan and bioavailability on Caenorhabditis elegans. 2011 Food Funct pmid:21776484
Sun B et al. Isorhamnetin inhibits Hâ‚‚Oâ‚‚-induced activation of the intrinsic apoptotic pathway in H9c2 cardiomyocytes through scavenging reactive oxygen species and ERK inactivation. 2012 J. Cell. Biochem. pmid:21948481
Yang ZG et al. Inhibitory effects of constituents from Euphorbia lunulata on differentiation of 3T3-L1 cells and nitric oxide production in RAW264.7 cells. 2011 Molecules pmid:21959301
Li G et al. Pharmacokinetic properties of isorhamnetin, kaempferol and quercetin after oral gavage of total flavones of Hippophae rhamnoides L. in rats using a UPLC-MS method. 2012 Fitoterapia pmid:22056665
Xie Q et al. Separation and purification of isorhamnetin 3-sulphate from Flaveria bidentis (L.) Kuntze by counter-current chromatography comparing two kinds of solvent systems. 2012 J Sep Sci pmid:22084024
Moalin M et al. A planar conformation and the hydroxyl groups in the B and C rings play a pivotal role in the antioxidant capacity of quercetin and quercetin derivatives. 2011 Molecules pmid:22105713