3-O-Methylquercetin

3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.

Cross Reference

Introduction

To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 3-O-Methylquercetin?

3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin

MeSH term MeSH ID Detail
Cell Transformation, Neoplastic D002471 126 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with 3-O-Methylquercetin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 3-O-Methylquercetin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 3-O-Methylquercetin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 3-O-Methylquercetin?

There are no associated biomedical information in the current reference collection.

What genes are associated with 3-O-Methylquercetin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 3-O-Methylquercetin?

Streptozotocin Diabetes

Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with 3-O-Methylquercetin

Download all related citations
Per page 10 20 50 100 | Total 307
Authors Title Published Journal PubMed Link
Hoek-van den Hil EF et al. Interference of flavonoids with enzymatic assays for the determination of free fatty acid and triglyceride levels. 2012 Anal Bioanal Chem pmid:22119999
Li J et al. Quercetin-3-methyl ether suppresses proliferation of mouse epidermal JB6 P+ cells by targeting ERKs. 2012 Carcinogenesis pmid:22139441
Li YC et al. Luteolin Suppresses Inflammatory Mediator Expression by Blocking the Akt/NFκB Pathway in Acute Lung Injury Induced by Lipopolysaccharide in Mice. 2012 Evid Based Complement Alternat Med pmid:22203870
Cho JM et al. Effects of physiological quercetin metabolites on interleukin-1β-induced inducible NOS expression. 2012 J. Nutr. Biochem. pmid:22221676
Raja MK et al. A comprehensive review on Nymphaea stellata: A traditionally used bitter. 2010 J Adv Pharm Technol Res pmid:22247863
Schrader C et al. Genistein as a potential inducer of the anti-atherogenic enzyme paraoxonase-1: studies in cultured hepatocytes in vitro and in rat liver in vivo. 2012 J. Cell. Mol. Med. pmid:22304296
Talib WH et al. Antiproliferative, antimicrobial and apoptosis inducing effects of compounds isolated from Inula viscosa. 2012 Molecules pmid:22418930
Zhang XQ et al. In vitro antioxidant and in vivo anti-inflammatory activities of Ophioglossum thermale. 2012 Am. J. Chin. Med. pmid:22419423
Shi C et al. Cellular stress response in Eca-109 cells inhibits apoptosis during early exposure to isorhamnetin. 2012 Neoplasma pmid:22489690
Wang DM et al. A new isorhamnetin glycoside and other phenolic compounds from Callianthemum taipaicum. 2012 Molecules pmid:22510608
Shi ZH et al. Metabolism-based synthesis, biologic evaluation and SARs analysis of O-methylated analogs of quercetin as thrombin inhibitors. 2012 Eur J Med Chem pmid:22647223
Napolitano JG et al. Complete 1H NMR spectral analysis of ten chemical markers of Ginkgo biloba. 2012 Magn Reson Chem pmid:22730238
Zhao G et al. Effects of solid dispersion and self-emulsifying formulations on the solubility, dissolution, permeability and pharmacokinetics of isorhamnetin, quercetin and kaempferol in total flavones of Hippophae rhamnoides L. 2013 Drug Dev Ind Pharm pmid:22757776
Si YX et al. Effects of isorhamnetin on tyrosinase: inhibition kinetics and computational simulation. 2012 Biosci. Biotechnol. Biochem. pmid:22790928
Kim TH et al. Anti-inflammatory activities of isorhamnetin-3-O-galactoside against HMGB1-induced inflammatory responses in both HUVECs and CLP-induced septic mice. 2013 J. Cell. Biochem. pmid:22930571
Clericuzio M et al. Flavonoid oligoglycosides from Ophioglossum vulgatum L. having wound healing properties. 2012 Planta Med. pmid:22936389
Wang H et al. Effect of the Miaoyao Fanggan sachet-derived isorhamnetin on TLR2/4 and NKp46 expression in mice. 2012 J Ethnopharmacol pmid:22974546
Wang SD et al. Inhibitory effect of Ginkgo biloba extract on fatty liver: regulation of carnitine palmitoyltransferase 1a and fatty acid metabolism. 2012 J Dig Dis pmid:22988926
Ramachandran L et al. Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer. 2012 J. Biol. Chem. pmid:22992727
Granica S et al. Novel insight into qualitative standardization of Polygoni avicularis herba (Ph. Eur.). 2013 J Pharm Biomed Anal pmid:23021006
Farag MA et al. Metabolome classification of Brassica napus L. organs via UPLC-QTOF-PDA-MS and their anti-oxidant potential. 2013 May-Jun Phytochem Anal pmid:23055344
Wang J et al. Phenolic compounds from Halimodendron halodendron (Pall.) voss and their antimicrobial and antioxidant activities. 2012 Int J Mol Sci pmid:23109858
Guo Y et al. Dietary fat increases quercetin bioavailability in overweight adults. 2013 Mol Nutr Food Res pmid:23319447
Paulke A et al. Isoquercitrin provides better bioavailability than quercetin: comparison of quercetin metabolites in body tissue and brain sections after six days administration of isoquercitrin and quercetin. 2012 Pharmazie pmid:23346761
Ku SK et al. Anticoagulant activities of persicarin and isorhamnetin. 2013 Vascul. Pharmacol. pmid:23391847
Gohlke A et al. Bioavailability of quercetin from its aglycone and its glucorhamnoside rutin in lactating dairy cows after intraduodenal administration. 2013 J. Dairy Sci. pmid:23403185
Jin JY et al. Isorhamnetin inhibits Prevotella intermedia lipopolysaccharide-induced production of interleukin-6 in murine macrophages via anti-inflammatory heme oxygenase-1 induction and inhibition of nuclear factor-κB and signal transducer and activator of transcription 1 activation. 2013 J. Periodont. Res. pmid:23441850
Fang R et al. Enhanced profiling of flavonol glycosides in the fruits of sea buckthorn (Hippophae rhamnoides). 2013 J. Agric. Food Chem. pmid:23517173
Ferreres F et al. Phenolic compounds from Jacaranda caroba (Vell.) A. DC.: approaches to neurodegenerative disorders. 2013 Food Chem. Toxicol. pmid:23524314
Sun J et al. Isorhamnetin protects against doxorubicin-induced cardiotoxicity in vivo and in vitro. 2013 PLoS ONE pmid:23724057
Yang JH et al. O-Methylated flavonol isorhamnetin prevents acute inflammation through blocking of NF-κB activation. 2013 Food Chem. Toxicol. pmid:23774260
Ge YB et al. Two new flavonol glycosides from the leaves of Elaeagnus pungens. 2013 J Asian Nat Prod Res pmid:23822169
Saud SM et al. Chemopreventive activity of plant flavonoid isorhamnetin in colorectal cancer is mediated by oncogenic Src and β-catenin. 2013 Cancer Res. pmid:23824743
He J et al. A sensitive LC-MS/MS method for simultaneous determination of six flavonoids in rat plasma: application to a pharmacokinetic study of total flavonoids from mulberry leaves. 2013 J Pharm Biomed Anal pmid:23850933
Kim JH et al. Enzyme-assisted extraction of cactus bioactive molecules under high hydrostatic pressure. 2014 J. Sci. Food Agric. pmid:23893871
Sabini MC et al. Evaluation of the cytotoxicity, genotoxicity and apoptotic induction of an aqueous extract of Achyrocline satureioides (Lam.) DC. 2013 Food Chem. Toxicol. pmid:23948353
Granica S et al. Antioxidant and anti-inflammatory flavonol glucuronides from Polygonum aviculare L. 2013 Fitoterapia pmid:24028968
Bakır T et al. Antioxidant/prooxidant effects of α-tocopherol, quercetin and isorhamnetin on linoleic acid peroxidation induced by Cu(II) and H2O2. 2014 Int J Food Sci Nutr pmid:24152374
Yang JH et al. Isorhamnetin protects against oxidative stress by activating Nrf2 and inducing the expression of its target genes. 2014 Toxicol. Appl. Pharmacol. pmid:24211276
Xu SL et al. Flavonoids induce the expression of synaptic proteins, synaptotagmin, and postsynaptic density protein-95 in cultured rat cortical neuron. 2013 Planta Med. pmid:24243544
Seo K et al. The antioxidant effects of isorhamnetin contribute to inhibit COX-2 expression in response to inflammation: a potential role of HO-1. 2014 Inflammation pmid:24337631
Li C et al. Isorhamnetin suppresses colon cancer cell growth through the PI3K‑Akt‑mTOR pathway. 2014 Mol Med Rep pmid:24398569
Castrillo JL and Carrasco L Action of 3-methylquercetin on poliovirus RNA replication. 1987 J. Virol. pmid:2442414
Xie Y et al. Phytic acid enhances the oral absorption of isorhamnetin, quercetin, and kaempferol in total flavones of Hippophae rhamnoides L. 2014 Fitoterapia pmid:24462958
Kawasaki T et al. Components of foods inhibit a drug exporter, human multidrug and toxin extrusion transporter 1. 2014 Biol. Pharm. Bull. pmid:24492725
Duan J et al. Transport characteristics of isorhamnetin across intestinal Caco-2 cell monolayers and the effects of transporters on it. 2014 Food Chem. Toxicol. pmid:24525098
Jayashankar B et al. Supercritical extract of Seabuckthorn Leaves (SCE200ET) inhibited endotoxemia by reducing inflammatory cytokines and nitric oxide synthase 2 expression. 2014 Int. Immunopharmacol. pmid:24594274
Bidone J et al. Simultaneous quantification of flavonoids from Achyrocline satureioides by a polar-reversed phase LC method--application to skin permeation/retention studies. 2014 Pharmazie pmid:24601216
Kim B et al. Eruca sativa and its flavonoid components, quercetin and isorhamnetin, improve skin barrier function by activation of peroxisome proliferator-activated receptor (PPAR)-α and suppression of inflammatory cytokines. 2014 Phytother Res pmid:24610745
Dou W et al. Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway. 2014 J. Nutr. Biochem. pmid:24913217