MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.
To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin
MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Justino GC et al. | Plasma quercetin metabolites: structure-antioxidant activity relationships. | 2004 | Arch. Biochem. Biophys. | pmid:15519302 |
Dubber MJ and Kanfer I | High-performance liquid chromatographic determination of selected flavonols in Ginkgo biloba solid oral dosage forms. | 2004 | J Pharm Pharm Sci | pmid:15576009 |
Hubbard GP et al. | Ingestion of quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in humans. | 2004 | J. Thromb. Haemost. | pmid:15613018 |
Ko WC et al. | Suppressive effects of 3-O-methylquercetin on ovalbumin-induced airway hyperresponsiveness. | 2004 | Planta Med. | pmid:15643544 |
Schulz HU et al. | Investigation of the bioavailability of hypericin, pseudohypericin, hyperforin and the flavonoids quercetin and isorhamnetin following single and multiple oral dosing of a hypericum extract containing tablet. | 2005 | Arzneimittelforschung | pmid:15727160 |
Oh HM et al. | Inhibitory activity of isorhamnetin from Persicaria thunbergii on Farnesyl Protein Transferase. | 2005 | Arch. Pharm. Res. | pmid:15789745 |
Bonaccorsi P et al. | Flavonol glucoside profile of southern Italian red onion (Allium cepa L.). | 2005 | J. Agric. Food Chem. | pmid:15796618 |
Lee YS et al. | Inhibitory effects of isorhamnetin-3-O-beta-D-glucoside from Salicornia herbacea on rat lens aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues. | 2005 | Biol. Pharm. Bull. | pmid:15863906 |
Wang Y et al. | Simultaneous determination of quercetin, kaempferol and isorhamnetin accumulated human breast cancer cells, by high-performance liquid chromatography. | 2005 | J Pharm Biomed Anal | pmid:15905060 |
Wang Y et al. | Involvement of P-glycoprotein in regulating cellular levels of Ginkgo flavonols: quercetin, kaempferol, and isorhamnetin. | 2005 | J. Pharm. Pharmacol. | pmid:15969930 |