| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
Total
1
3-O-Methylquercetin
3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.
Cross Reference
Introduction
To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 3-O-Methylquercetin?
3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin
PubChem Associated disorders and diseases
What pathways are associated with 3-O-Methylquercetin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 3-O-Methylquercetin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 3-O-Methylquercetin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 3-O-Methylquercetin?
There are no associated biomedical information in the current reference collection.
What genes are associated with 3-O-Methylquercetin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 3-O-Methylquercetin?
Streptozotocin Diabetes
Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with 3-O-Methylquercetin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Morand C et al. | Plasma metabolites of quercetin and their antioxidant properties. | 1998 | Am. J. Physiol. | pmid:9688981 |
| da Silva EL et al. | Quercetin metabolites inhibit copper ion-induced lipid peroxidation in rat plasma. | 1998 | FEBS Lett. | pmid:9688581 |
| Yang F et al. | Multidimensional counter-current chromatographic system and its application. | 1998 | J Chromatogr A | pmid:9604337 |
| Boers F et al. | An improved synthesis of the anti-picornavirus flavone 3-O-methylquercetin. | 1997 | Arch. Pharm. (Weinheim) | pmid:9396391 |
| Lin CN et al. | Novel antiplatelet naphthalene from Rhamnus nakaharai. | 1995 | J. Nat. Prod. | pmid:8691213 |
| Czeczot H and Kusztelak J | A study of the genotoxic potential of flavonoids using short-term bacterial assays. | 1993 | Acta Biochim. Pol. | pmid:8140830 |
| Igarashi K and Ohmuma M | Effects of isorhamnetin, rhamnetin, and quercetin on the concentrations of cholesterol and lipoperoxide in the serum and liver and on the blood and liver antioxidative enzyme activities of rats. | 1995 | Biosci. Biotechnol. Biochem. | pmid:7772823 |
| Park JC et al. | Isorhamnetin sulphate from the leaves and stems of Oenanthe javanica in Korea. | 1995 | Planta Med. | pmid:7480193 |
| Goodwin RS et al. | Flavonoids from Brickellia glutinosa. | 1984 Jul-Aug | J. Nat. Prod. | pmid:6436442 |
| Khouri HE et al. | Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. III. Purification and kinetic analysis of S-adenosyl-L-methionine:3-methylquercetin 7-O-methyltransferase. | 1988 | Arch. Biochem. Biophys. | pmid:3415239 |
| Castrillo JL and Carrasco L | Adenovirus late protein synthesis is resistant to the inhibition of translation induced by poliovirus. | 1987 | J. Biol. Chem. | pmid:3034890 |
| Šarić Mustapić D et al. | The Inhibitory Effect of Flavonoid Aglycones on the Metabolic Activity of CYP3A4 Enzyme. | 2018 | Molecules | pmid:30301254 |
| Bonneau AM and Sonenberg N | Proteolysis of the p220 component of the cap-binding protein complex is not sufficient for complete inhibition of host cell protein synthesis after poliovirus infection. | 1987 | J. Virol. | pmid:3029432 |
| Vrijsen R et al. | The poliovirus-induced shut-off of cellular protein synthesis persists in the presence of 3-methylquercetin, a flavonoid which blocks viral protein and RNA synthesis. | 1987 | Antiviral Res. | pmid:3026245 |
| Rombaut B et al. | Comparison of arildone and 3-methylquercetin as stabilizers of poliovirus. | 1985 | Antiviral Res. | pmid:3002268 |
| Wu Q et al. | Differential Effects of Quercetin and Two of Its Derivatives, Isorhamnetin and Isorhamnetin-3-glucuronide, in Inhibiting the Proliferation of Human Breast-Cancer MCF-7 Cells. | 2018 | J. Agric. Food Chem. | pmid:29905475 |
| Zhu JX et al. | Quercetin, Kaempferol and Isorhamnetin in Elaeagnus pungens Thunb. Leaf: Pharmacological Activities and Quantitative Determination Studies. | 2018 | Chem. Biodivers. | pmid:29802806 |
| Zhao TT et al. | Isorhamnetin protects against hypoxia/reoxygenation-induced injure by attenuating apoptosis and oxidative stress in H9c2 cardiomyocytes. | 2018 | Gene | pmid:29730426 |
| Qi F et al. | Anti-inflammatory effects of isorhamnetin on LPS-stimulated human gingival fibroblasts by activating Nrf2 signaling pathway. | 2018 | Microb. Pathog. | pmid:29704670 |
| Lu X et al. | Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice. | 2018 | Biomed. Pharmacother. | pmid:29684859 |
| Quintero-Soto MF et al. | Phenolic profiles and their contribution to the antioxidant activity of selected chickpea genotypes from Mexico and ICRISAT collections. | 2018 | Plant Foods Hum Nutr | pmid:29516285 |
| Yamauchi K and Mitsunaga T | Methylquercetins stimulate melanin biosynthesis in a three-dimensional skin model. | 2018 | J Nat Med | pmid:29442220 |
| Shi H et al. | Isorhamnetin, the active constituent of a Chinese herb Hippophae rhamnoides L, is a potent suppressor of dendritic-cell maturation and trafficking. | 2018 | Int. Immunopharmacol. | pmid:29272818 |
| Bhattacharya D et al. | Antibacterial activity of polyphenolic fraction of Kombucha against Vibrio cholerae: targeting cell membrane. | 2018 | Lett. Appl. Microbiol. | pmid:29193174 |
| Wang JY et al. | Network pharmacological mechanisms of Vernonia anthelmintica (L.) in the treatment of vitiligo: Isorhamnetin induction of melanogenesis via up-regulation of melanin-biosynthetic genes. | 2017 | BMC Syst Biol | pmid:29145845 |
| Wang J et al. | Isorhamnetin prevents H2O2‑induced oxidative stress in human retinal pigment epithelial cells. | 2018 | Mol Med Rep | pmid:29115489 |
| Ressaissi A et al. | Isorhamnetin derivatives and piscidic acid for hypercholesterolemia: cholesterol permeability, HMG-CoA reductase inhibition, and docking studies. | 2017 | Arch. Pharm. Res. | pmid:28936788 |
| Antunes-Ricardo M et al. | Bioaccessibility, Intestinal Permeability and Plasma Stability of Isorhamnetin Glycosides from Opuntia ficus-indica (L.). | 2017 | Int J Mol Sci | pmid:28829356 |
| Olennikov DN et al. | Isorhamnetin and Quercetin Derivatives as Anti-Acetylcholinesterase Principles of Marigold (Calendula officinalis) Flowers and Preparations. | 2017 | Int J Mol Sci | pmid:28767066 |
| Li J et al. | Isorhamnetin inhibits IL‑1β‑induced expression of inflammatory mediators in human chondrocytes. | 2017 | Mol Med Rep | pmid:28731170 |
| Qiu L et al. | Protective effects of isorhamnetin on N2a cell against endoplasmic reticulum stress-induced injury is mediated by PKCε. | 2017 | Biomed. Pharmacother. | pmid:28715866 |
| Bouratoua A et al. | Chemical composition and antioxidant activity of aerial parts of Ferula longipes Coss. ex Bonnier and Maury. | 2018 | Nat. Prod. Res. | pmid:28714345 |
| Vrijsen R et al. | Antiviral activity of flavones and potentiation by ascorbate. | 1988 | J. Gen. Virol. | pmid:2839607 |
| Shi W et al. | Bioactive flavonoids from Flos Sophorae. | 2017 | J Nat Med | pmid:28357634 |
| Östlund J et al. | In vitro inhibition of human CYP2E1 and CYP3A by quercetin and myricetin in hepatic microsomes is not gender dependent. | 2017 | Toxicology | pmid:28232125 |
| Mikulic-Petkovsek M et al. | Bioactive Components and Antioxidant Capacity of Fruits from Nine Sorbus Genotypes. | 2017 | J. Food Sci. | pmid:28182841 |
| Gao L et al. | Isorhamnetin protects against cardiac hypertrophy through blocking PI3K-AKT pathway. | 2017 | Mol. Cell. Biochem. | pmid:28176246 |
| Van Hoof L et al. | Plant antiviral agents, VI. Isolation of antiviral phenolic glucosides from Populus cultivar Beaupre by droplet counter-current chromatography. | 1989 Jul-Aug | J. Nat. Prod. | pmid:2809612 |
| Guo R et al. | Comparative assessment of phytochemical profiles, antioxidant and antiproliferative activities of Sea buckthorn (Hippophaë rhamnoides L.) berries. | 2017 | Food Chem | pmid:27979305 |
| Neveux S et al. | Natural Compounds as Occult Ototoxins? Ginkgo biloba Flavonoids Moderately Damage Lateral Line Hair Cells. | 2017 | J. Assoc. Res. Otolaryngol. | pmid:27896487 |
| Tian Y et al. | Phenolic compounds extracted by acidic aqueous ethanol from berries and leaves of different berry plants. | 2017 | Food Chem | pmid:27855899 |
| Seo S et al. | Isorhamnetin Inhibits Reactive Oxygen Species-Dependent Hypoxia Inducible Factor (HIF)-1α Accumulation. | 2016 | Biol. Pharm. Bull. | pmid:27803454 |
| Van Puyvelde L et al. | Isolation of flavonoids and a chalcone from Helichrysum odoratissimum and synthesis of helichrysetin. | 1989 May-Jun | J. Nat. Prod. | pmid:2778452 |
| Mudrić SŽ et al. | The polyphenolics and carbohydrates as indicators of botanical and geographical origin of Serbian autochthonous clones of red spice paprika. | 2017 | Food Chem | pmid:27664689 |
| Ferreres F et al. | HPLC-DAD-ESI/MS(n) profiling of phenolic compounds from Lathyrus cicera L. seeds. | 2017 | Food Chem | pmid:27507525 |
| Mata A et al. | Contribution to the characterization of Opuntia spp. juices by LC-DAD-ESI-MS/MS. | 2016 | Food Chem | pmid:27211682 |
| Lee YG et al. | Change in Flavonoid Composition and Antioxidative Activity during Fermentation of Onion (Allium cepa L.) by Leuconostoc mesenteroides with Different Salt Concentrations. | 2016 | J. Food Sci. | pmid:27175820 |
| Zhao JJ et al. | Treatment with Isorhamnetin Protects the Brain Against Ischemic Injury in Mice. | 2016 | Neurochem. Res. | pmid:27161367 |
| Yang JH et al. | Isorhamnetin attenuates liver fibrosis by inhibiting TGF-β/Smad signaling and relieving oxidative stress. | 2016 | Eur. J. Pharmacol. | pmid:27151496 |
| Li Y et al. | Isorhamnetin ameliorates LPS-induced inflammatory response through downregulation of NF-κB signaling. | 2016 | Inflammation | pmid:27138362 |