3-O-Methylquercetin

3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.

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Introduction

To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 3-O-Methylquercetin?

3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin

MeSH term MeSH ID Detail
Cell Transformation, Neoplastic D002471 126 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with 3-O-Methylquercetin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 3-O-Methylquercetin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 3-O-Methylquercetin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 3-O-Methylquercetin?

There are no associated biomedical information in the current reference collection.

What genes are associated with 3-O-Methylquercetin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 3-O-Methylquercetin?

Streptozotocin Diabetes

Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with 3-O-Methylquercetin

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Authors Title Published Journal PubMed Link
pmid:
Czeczot H The effect of flavonoids on the mutagenic activity of aromatic amines. 1992 Acta Biochim. Pol. pmid:1441824
Czeczot H and Kusztelak J A study of the genotoxic potential of flavonoids using short-term bacterial assays. 1993 Acta Biochim. Pol. pmid:8140830
Lan K et al. Intra-herb pharmacokinetics interaction between quercetin and isorhamentin. 2008 Acta Pharmacol. Sin. pmid:18954533
Smolarz HD Comparative study on the free flavonoid aglycones in herbs of different species of Polygonum L. 2002 Mar-Apr Acta Pol Pharm pmid:12365607
Nazaruk J and Gudej J Qualitative and quantitative chromatographic investigation of flavonoids in Bellis perennis L. 2001 Sep-Oct Acta Pol Pharm pmid:11876448
Sikorska M and Matławska I Kaempferol, isorhamnetin and their glycosides in the flowers of Asclepias syriaca L. 2001 Jul-Aug Acta Pol Pharm pmid:11693731
Zhang XQ et al. In vitro antioxidant and in vivo anti-inflammatory activities of Ophioglossum thermale. 2012 Am. J. Chin. Med. pmid:22419423
Morand C et al. Plasma metabolites of quercetin and their antioxidant properties. 1998 Am. J. Physiol. pmid:9688981
Hoek-van den Hil EF et al. Interference of flavonoids with enzymatic assays for the determination of free fatty acid and triglyceride levels. 2012 Anal Bioanal Chem pmid:22119999
Robin V et al. Antipoliovirus flavonoids from Psiadia dentata. 2001 Antivir. Chem. Chemother. pmid:11900347
Lopez Pila JM et al. Lack of evidence for strand-specific inhibition of poliovirus RNA synthesis by 3-methylquercetin. 1989 Antiviral Res. pmid:2540709
Vrijsen R et al. The poliovirus-induced shut-off of cellular protein synthesis persists in the presence of 3-methylquercetin, a flavonoid which blocks viral protein and RNA synthesis. 1987 Antiviral Res. pmid:3026245
Rombaut B et al. Comparison of arildone and 3-methylquercetin as stabilizers of poliovirus. 1985 Antiviral Res. pmid:3002268
Khouri HE et al. Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. III. Purification and kinetic analysis of S-adenosyl-L-methionine:3-methylquercetin 7-O-methyltransferase. 1988 Arch. Biochem. Biophys. pmid:3415239
Murota K et al. Efficiency of absorption and metabolic conversion of quercetin and its glucosides in human intestinal cell line Caco-2. 2000 Arch. Biochem. Biophys. pmid:11368329
Lu HW et al. Effect of three flavonoids, 5,7,3',4'-tetrahydroxy-3-methoxy flavone, luteolin, and quercetin, on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophil. 2001 Arch. Biochem. Biophys. pmid:11516163
Steffen Y et al. Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase. 2008 Arch. Biochem. Biophys. pmid:17996190
Justino GC et al. Plasma quercetin metabolites: structure-antioxidant activity relationships. 2004 Arch. Biochem. Biophys. pmid:15519302
Boers F et al. An improved synthesis of the anti-picornavirus flavone 3-O-methylquercetin. 1997 Arch. Pharm. (Weinheim) pmid:9396391