MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.
To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin
MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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pmid: | ||||
Guo Y et al. | Quercetin bioavailability is associated with inadequate plasma vitamin C status and greater plasma endotoxin in adults. | Nutrition | pmid:25280405 | |
Goodwin RS et al. | Flavonoids from Brickellia glutinosa. | 1984 Jul-Aug | J. Nat. Prod. | pmid:6436442 |
Rombaut B et al. | Comparison of arildone and 3-methylquercetin as stabilizers of poliovirus. | 1985 | Antiviral Res. | pmid:3002268 |
Vrijsen R et al. | The poliovirus-induced shut-off of cellular protein synthesis persists in the presence of 3-methylquercetin, a flavonoid which blocks viral protein and RNA synthesis. | 1987 | Antiviral Res. | pmid:3026245 |
Bonneau AM and Sonenberg N | Proteolysis of the p220 component of the cap-binding protein complex is not sufficient for complete inhibition of host cell protein synthesis after poliovirus infection. | 1987 | J. Virol. | pmid:3029432 |
Castrillo JL and Carrasco L | Adenovirus late protein synthesis is resistant to the inhibition of translation induced by poliovirus. | 1987 | J. Biol. Chem. | pmid:3034890 |
Castrillo JL and Carrasco L | Action of 3-methylquercetin on poliovirus RNA replication. | 1987 | J. Virol. | pmid:2442414 |
Vrijsen R et al. | Antiviral activity of flavones and potentiation by ascorbate. | 1988 | J. Gen. Virol. | pmid:2839607 |
Khouri HE et al. | Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. III. Purification and kinetic analysis of S-adenosyl-L-methionine:3-methylquercetin 7-O-methyltransferase. | 1988 | Arch. Biochem. Biophys. | pmid:3415239 |
Lopez Pila JM et al. | Lack of evidence for strand-specific inhibition of poliovirus RNA synthesis by 3-methylquercetin. | 1989 | Antiviral Res. | pmid:2540709 |
Guinea R et al. | Modification of phospholipase C and phospholipase A2 activities during poliovirus infection. | 1989 | J. Biol. Chem. | pmid:2557346 |
Van Hoof L et al. | Plant antiviral agents, VI. Isolation of antiviral phenolic glucosides from Populus cultivar Beaupre by droplet counter-current chromatography. | 1989 Jul-Aug | J. Nat. Prod. | pmid:2809612 |
Van Puyvelde L et al. | Isolation of flavonoids and a chalcone from Helichrysum odoratissimum and synthesis of helichrysetin. | 1989 May-Jun | J. Nat. Prod. | pmid:2778452 |
Czeczot H | The effect of flavonoids on the mutagenic activity of aromatic amines. | 1992 | Acta Biochim. Pol. | pmid:1441824 |
Czeczot H and Kusztelak J | A study of the genotoxic potential of flavonoids using short-term bacterial assays. | 1993 | Acta Biochim. Pol. | pmid:8140830 |
Lin CN et al. | Novel antiplatelet naphthalene from Rhamnus nakaharai. | 1995 | J. Nat. Prod. | pmid:8691213 |
Igarashi K and Ohmuma M | Effects of isorhamnetin, rhamnetin, and quercetin on the concentrations of cholesterol and lipoperoxide in the serum and liver and on the blood and liver antioxidative enzyme activities of rats. | 1995 | Biosci. Biotechnol. Biochem. | pmid:7772823 |
Park JC et al. | Isorhamnetin sulphate from the leaves and stems of Oenanthe javanica in Korea. | 1995 | Planta Med. | pmid:7480193 |
Boers F et al. | An improved synthesis of the anti-picornavirus flavone 3-O-methylquercetin. | 1997 | Arch. Pharm. (Weinheim) | pmid:9396391 |